Objective: to identify signs of endothelial dysfunction of the cardiovascular system in overweight and obese children. Materials and methods: Comprehensively examined 52 children and adolescents aged 8 to 16 years with exogenous constitutional obesity. Results: In the study of endothelial dysfunction, an excess of recognized markers was revealed: albuminuria (AU), endothelin-1 (ET-1), von Willebrand factor (VWF) activity, and IL-6 levels in the group with obesity and changes in the cardiovascular system compared with comparison group. And also revealed a decrease in the secretion of adiponectin in obesity. Conclusions. Endothelial dysfunction and metabolic syndrome are closely linked and form a continuous cycle leading to metabolic and cardiovascular diseases.
| Mualliflar | Холмурадова Зилола Эргашевна |
|---|---|
| Jurnal | Марказий Осиё эндокринологик журнали |
| Nashr sanasi | 2025-08-28 |
| Jild | 5 |
| Son | 2 |
| Til | O‘zbek |
ожирение, дети, эндотелиальная дисфункция, сердечно-сосудистая система, obesity, children, endothelial dysfunction, cardiovascular system, semizlik, bolalar, endotelial disfunktsiya, yurak-qon tomir tizimi
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