Enhancing intensive care for patients following coronary artery bypass grafting (literature review)

YUSUPOV Jasur Tolibovich, MATLUBOV Mansur Muratovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

Among the leading causes of death in the adult population, coronary heart disease (CHD) is one of the foremost. Both international and Russian guidelines for the treatment of CHD recommend a collaborative approach when selecting surgical revascularization, particularly coronary artery bypass grafting (CABG). Generally, CABG can be performed using two types of surgical interventions: one with cardiopulmonary bypass (CPB) and cardiac arrest, and another on a beating heart without CPB. The key difference between these approaches lies in the use of CPB and the stoppage of the heart during surgery in the first method, while the second involves surgery on a functioning heart. Both surgical interventions and the use of CPB activate the complement system and trigger the release of cytokines, leading to a systemic inflammatory response. IL-6, IL-1b, and tumor necrosis factor alpha (TNF-a) are the primary mediators of the acute phase of the inflammatory response. Analysis indicates that the early postoperative administration of ulinastatin inhibits the sequestration and activation of neutrophils, reduces the typical postoperative rise in cytokine levels, and alleviates systemic inflammatory response syndrome, pulmonary microvessel permeability, and postoperative pulmonary edema.

Maqola ma’lumotlari
MualliflarYUSUPOV Jasur Tolibovich, MATLUBOV Mansur Muratovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-03-18
Jild10
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-09-13

Kalit so‘zlar

ишемическая болезнь сердца, аортокоронарное шунтирование, искусственное кровообращение, цитокины, улинастатин, синдром системной воспалительной реакции, coronary heart disease, coronary artery bypass grafting, artificial blood circulation, cytokines, ulinastatin, systemic inflammatory reaction syndrome, yurak ishemik kasalligi, aortokoronar shuntlash, sun'iy qon aylanish, sitokinlar, ulinitatin, tizimli yallig'lanish reaksiyasi sindromi

Ilmiy soha

Iqtibos keltirish

APAYUSUPOV Jasur Tolibovich, & MATLUBOV Mansur Muratovich (2025). ENHANCING INTENSIVE CARE FOR PATIENTS FOLLOWING CORONARY ARTERY BYPASS GRAFTING (LITERATURE REVIEW). Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1). https://tadqiqot.uz/index.php/biomedicine/article/view/11114
GOST (OAK)YUSUPOV Jasur Tolibovich, MATLUBOV Mansur Muratovich ENHANCING INTENSIVE CARE FOR PATIENTS FOLLOWING CORONARY ARTERY BYPASS GRAFTING (LITERATURE REVIEW) // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 1.
MLAYUSUPOV Jasur Tolibovich, and MATLUBOV Mansur Muratovich. “ENHANCING INTENSIVE CARE FOR PATIENTS FOLLOWING CORONARY ARTERY BYPASS GRAFTING (LITERATURE REVIEW).” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/11114
ChicagoYUSUPOV Jasur Tolibovich, and MATLUBOV Mansur Muratovich. “ENHANCING INTENSIVE CARE FOR PATIENTS FOLLOWING CORONARY ARTERY BYPASS GRAFTING (LITERATURE REVIEW).” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/11114
HarvardYUSUPOV Jasur Tolibovich, and MATLUBOV Mansur Muratovich (2025) ‘ENHANCING INTENSIVE CARE FOR PATIENTS FOLLOWING CORONARY ARTERY BYPASS GRAFTING (LITERATURE REVIEW)’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1). https://tadqiqot.uz/index.php/biomedicine/article/view/11114
BibTeX
@article{yusupovjasurtolibovich2025,
  title = {ENHANCING INTENSIVE CARE FOR PATIENTS FOLLOWING CORONARY ARTERY BYPASS GRAFTING (LITERATURE REVIEW)},
  author = {YUSUPOV Jasur Tolibovich and MATLUBOV Mansur Muratovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {1},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/11114}
}

Boshqa maqola uchun iqtibos tayyorlash

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali jurnalidan boshqa maqolalar

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali — barcha maqolalar · 2025-yil arxivi

YUSUPOV Jasur Tolibovich — boshqa maqolalari

Tibbiyot sohasidagi boshqa maqolalar

Tibbiyot sohasidagi OAK jurnallari