Endothelial dysfunction plays an important role in the development of many diseases and conditions, including the active phase of the new coronavirus infection COVID-19 and post-Covid syndrome. Systemic angiopathy, which is associated with endothelial dysfunction and is characterized by extensive damage to the microcirculatory system, including endotheliitis, has certain morphological manifestations that are characteristic of COVID-19. The SARS-CoV-2 virus specifically attacks goblet cells in the mucous membrane of the respiratory tract. COVID-19 progresses through diffuse alveolar damage, leading to hyaline membrane formation and pulmonary edema. This damage to the respiratory tract is caused by the effects of the SARS-CoV-2 virus on alveolar epithelial cells and endothelial cells, as well as immunological effects, including perivascular inflammation. All these factors together lead to disruption of the endothelial-epithelial barrier and the penetration of protein exudate into the alveolar space, creating a background for bacterial and fungal flora.
| Mualliflar | SAMIBAEVA Umida Khurshidovn |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2024-09-04 |
| Jild | 9 |
| Son | 3 |
| Til | Rus |
The problem of measles infection is caused by the widespread spread, high contagiousness, and the defeat of all age groups of the population. World-class experts have…
Vaccination is an effective and cost-effective method of preventing infectious diseases. The introduction of the vaccine against measles, mumps and rubella into the national vaccination calendar of the republic in 2007…
In recent years, retinal diseases have become one of the main problems of vision loss in the world. Blindness and low vision among patients with retinal pathologies occurs in 12.5% of cases due to age-related macular…
Acromegaly is a disease characterized by growth hormone (GH) hypersecretion, multisystem comorbidities, and increased mortality (1, 2).Some studies estimate the incidence of acromegaly to be 86-240 people per million…
Erectile dysfunction (ED) is an important health problem in men associated with reduced quality of life. Implementation of phosphodiesterase type 5 inhibitors (PDE-5 Is) has revolutionized the management of patients…
The article presents the results of a review of the literature on the forensic aspects of injuries associated with people falling out of the passenger compartment (body) of a moving car. Attention is drawn to the sharp…
The purpose of this article is to summarize research data on the use of MKRA in various pathologies. Information about aldosterone and mineralocorticoid receptors is summarized. Also, the clinical pharmacology of MKRA…
The article provides data indicating the scientific direction of iridology. Until now, many researchers have provided very contradictory arguments in favor and against the scientific approach of iridology methods. This…
In 16.7% of women who give birth with mixed vegetative reactivity with normochromic blood parameters, the reactivity of the body is hyperadaptive, the duration of labor is 16.4 hours. In 73.3% of women who give birth…
The article discusses the possibilities of iridodiagnostics in the clinic and in forensic practice, provides data on the history of its occurrence, and different points of view when interpreting the emerging structural…
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