Endothelial dysfunction plays an important role in the development of many diseases and conditions, including the active phase of the new coronavirus infection COVID-19 and post-Covid syndrome. Systemic angiopathy, which is associated with endothelial dysfunction and is characterized by extensive damage to the microcirculatory system, including endotheliitis, has certain morphological manifestations that are characteristic of COVID-19. The SARS-CoV-2 virus specifically attacks goblet cells in the mucous membrane of the respiratory tract. COVID-19 progresses through diffuse alveolar damage, leading to hyaline membrane formation and pulmonary edema. This damage to the respiratory tract is caused by the effects of the SARS-CoV-2 virus on alveolar epithelial cells and endothelial cells, as well as immunological effects, including perivascular inflammation. All these factors together lead to disruption of the endothelial-epithelial barrier and the penetration of protein exudate into the alveolar space, creating a background for bacterial and fungal flora.
| Mualliflar | SAMIBAEVA Umida Khurshidovn |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashriyot | Тошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ |
| ISSN | 2181-9300 |
| Nashr sanasi | 2024-09-04 |
| Jild | 9 |
| Son | 3 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-27 |
| APA | SAMIBAEVA Umida Khurshidovn (2024). THE SIGNIFICANCE OF ENDOTHELIAL DYSFUNCTION IN THE NEW CORONAVIRUS INFECTION COVID-19. (LITERATURE REVIEW). Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(3). https://tadqiqot.uz/index.php/biomedicine/article/view/10086 |
|---|---|
| GOST (OAK) | SAMIBAEVA Umida Khurshidovn THE SIGNIFICANCE OF ENDOTHELIAL DYSFUNCTION IN THE NEW CORONAVIRUS INFECTION COVID-19. (LITERATURE REVIEW) // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2024. – T. 9, № 3. |
| MLA | SAMIBAEVA Umida Khurshidovn. “THE SIGNIFICANCE OF ENDOTHELIAL DYSFUNCTION IN THE NEW CORONAVIRUS INFECTION COVID-19. (LITERATURE REVIEW).” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(3), 2024. https://tadqiqot.uz/index.php/biomedicine/article/view/10086 |
| Chicago | SAMIBAEVA Umida Khurshidovn. “THE SIGNIFICANCE OF ENDOTHELIAL DYSFUNCTION IN THE NEW CORONAVIRUS INFECTION COVID-19. (LITERATURE REVIEW).” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(3) (2024). https://tadqiqot.uz/index.php/biomedicine/article/view/10086 |
| Harvard | SAMIBAEVA Umida Khurshidovn (2024) ‘THE SIGNIFICANCE OF ENDOTHELIAL DYSFUNCTION IN THE NEW CORONAVIRUS INFECTION COVID-19. (LITERATURE REVIEW)’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(3). https://tadqiqot.uz/index.php/biomedicine/article/view/10086 |
| BibTeX | @article{samibaevaumidakhurshidovn2024,
title = {THE SIGNIFICANCE OF ENDOTHELIAL DYSFUNCTION IN THE NEW CORONAVIRUS INFECTION COVID-19. (LITERATURE REVIEW)},
author = {SAMIBAEVA Umida Khurshidovn},
journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
year = {2024},
volume = {9},
number = {3},
url = {https://tadqiqot.uz/index.php/biomedicine/article/view/10086}
} |
Boshqa maqola uchun iqtibos tayyorlash
Shoulder joint injury is one of the most common pathologies of large joints and accounts for 16 to 55% of cases according to the literature. Pain in the shoulder joint is the third most common among all musculoskeletal…
The article discusses the possibilities of iridodiagnostics in the clinic and in forensic practice, provides data on the history of its occurrence, and different points of view when interpreting the emerging structural…
The article presents the results of a review of the literature on the forensic aspects of injuries associated with people falling out of the passenger compartment (body) of a moving car. Attention is drawn to the sharp…
Acromegaly is a disease characterized by growth hormone (GH) hypersecretion, multisystem comorbidities, and increased mortality (1, 2).Some studies estimate the incidence of acromegaly to be 86-240 people per million…
Vaccination is an effective and cost-effective method of preventing infectious diseases. The introduction of the vaccine against measles, mumps and rubella into the national vaccination calendar of the republic in 2007…
The problem of measles infection is caused by the widespread spread, high contagiousness, and the defeat of all age groups of the population. World-class experts have concluded that due to vaccination, complete…
In recent years, retinal diseases have become one of the main problems of vision loss in the world. Blindness and low vision among patients with retinal pathologies occurs in 12.5% of cases due to age-related macular…
Erectile dysfunction (ED) is an important health problem in men associated with reduced quality of life. Implementation of phosphodiesterase type 5 inhibitors (PDE-5 Is) has revolutionized the management of patients…
The purpose of this article is to summarize research data on the use of MKRA in various pathologies. Information about aldosterone and mineralocorticoid receptors is summarized. Also, the clinical pharmacology of MKRA…
In 16.7% of women who give birth with mixed vegetative reactivity with normochromic blood parameters, the reactivity of the body is hyperadaptive, the duration of labor is 16.4 hours. In 73.3% of women who give birth…
Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali — barcha maqolalar · 2024-yil arxivi
The purpose of this study is to compare the nature of the clinical course of measles in children under one year of age who were breastfed with those who were bottle-fed. The clinical diagnosis of measles was established…
A review of the literature data shows that the main complication in patients with COVID-19, which determines the severity of the disease and fatal outcomes, remains pneumonia in all countries of the world, the etiology…
Bacterial complications of COVID-19 are very common and directly impact the severity and outcome of the disease. This study identified a spectrum of clinically significant bacterial pathogens in samples collected from…
A prospective study of 163 patients with the new coronavirus infection COVID-19, hospitalized in the Samarkand Regional Specialized Medical Center for the period 2020-2022, was conducted. The level of vascular…
This study addresses the significance of vascular endothelial growth factor A (VEGF-A) as a potential biomarker of endothelial dysfunction in individuals with severe manifestations of COVID-19, particularly those with…
An analysis of clinical and laboratory data was conducted on 210 patients with moderate and severe forms of COVID-19 hospitalized in the clinic of the Samarkand Regional Specialized Medical Center in the period…
Настоящее исследование посвящено разработке алгоритма раннего выявления сенсоневральной тугоухости у детей с использованием методов полимеразной цепной реакции (ПЦР). Обследовано 235 детей с нарушениями слуха, из…
В статье представлены клинические аспекты и диагностические проблемы выявления сенсоневральной тугоухости у новорождённых с перинатальной патологией. Обследовано 115 новорождённых, из которых 35 перенесли асфиксию, а у…
Сенсоневральная тугоухость (СНТ) у детей остаётся одной из наиболее актуальных проблем современной оториноларингологии и медицинской генетики. Ранняя диагностика нарушений слуха играет ключевую роль в предупреждении…
Сенсоневральная тугоухость у новорождённых является одной из ведущих причин нарушения слухоречевого развития и ранней инвалидизации. Наиболее уязвимыми считаются дети, перенёсшие перинатальные осложнения, такие как…
Mazkur eksperimental tadqiqotda yuqori yog‘li ratsion va seftriaksonning lipid hamda uglevod almashinuviga alohida va birgalikdagi ta’siri 160 ta oq zotsiz erkak kalamushda o‘rganildi. Tajriba hayvonlari to‘rtta guruhga…
Мазкур тадқиқотда Тошкет вилоятидаги Ўрта Чирчиқ тумани 25-сонли, Бўка тумани 3-сонли ва 9-сонли давлат мактабгача таълим ташкилотларида 2025 йил ёз мавсумидаги таомномаларнинг озиқ-овқат маҳсулотлари билан…