Markers of inflammation in bronchial asthma in children with consequences of perinatal lesion to the central nervous system

KHAIDAROVA Sarvinoz Khaidarzhonovna, MAVLYANOVA Zilola Farkhadovna

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2024-yil

Annotatsiya

Aim: to study the features of the course of bronchial asthma in children with perinatal damage to the central nervous system. Materials and methods: The study is based on data from a comprehensive examination of 90 children, divided into two groups, comparable by gender and age. There 53 children aged 5 to 11 years with BA due to the consequences of perinatal central nervous system damage made up the main group. The comparison group consisted of 37 children aged 6 to 11 years with asthma without concomitant neurological symptoms. Results: The studies conducted showed that in the sick children with asthma we examined against the background of the consequences of perinatal damage to the CNS, pronounced changes in intercellular immune mechanisms were observed. The revealed direction of immune changes and their severity indicate the important pathogenetic role of immune mechanisms in the development and progression of changes in the state of the immune system in children with BA with concomitant damage to the CNS of functional origin. Conclusions: It was found that children in the main group had lower indicators of physical activity and PEF in relation to the indicators of children in the comparison group. A comparative analysis of the cytokine status of children with BA against the background of the consequences of perinatal damage to the central nervous system with data from children with asthma without concomitant neurological symptoms showed a significant imbalance and significantly high levels of IL-6, IL-8 and TNF-α in the main group of patients.

Maqola ma’lumotlari
MualliflarKHAIDAROVA Sarvinoz Khaidarzhonovna, MAVLYANOVA Zilola Farkhadovna
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2024-04-14
Jild9
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

бронхиальная астма, дети, маркеры воспаления, центральная нервная система, перинатальное поражение, bronchial asthma, children, inflammatory markers, central nervous system, perinatal damage, bronxial astma, bolalar, yallig'lanish belgilari, мarkaziy asab tizimi, perinatal shikastlanish

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAKHAIDAROVA Sarvinoz Khaidarzhonovna, & MAVLYANOVA Zilola Farkhadovna (2024). MARKERS OF INFLAMMATION IN BRONCHIAL ASTHMA IN CHILDREN WITH CONSEQUENCES OF PERINATAL LESION TO THE CENTRAL NERVOUS SYSTEM. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(1). https://tadqiqot.uz/index.php/biomedicine/article/view/9249
GOST (OAK)KHAIDAROVA Sarvinoz Khaidarzhonovna, MAVLYANOVA Zilola Farkhadovna MARKERS OF INFLAMMATION IN BRONCHIAL ASTHMA IN CHILDREN WITH CONSEQUENCES OF PERINATAL LESION TO THE CENTRAL NERVOUS SYSTEM // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2024. – T. 9, № 1.
MLAKHAIDAROVA Sarvinoz Khaidarzhonovna, and MAVLYANOVA Zilola Farkhadovna. “MARKERS OF INFLAMMATION IN BRONCHIAL ASTHMA IN CHILDREN WITH CONSEQUENCES OF PERINATAL LESION TO THE CENTRAL NERVOUS SYSTEM.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(1), 2024. https://tadqiqot.uz/index.php/biomedicine/article/view/9249
ChicagoKHAIDAROVA Sarvinoz Khaidarzhonovna, and MAVLYANOVA Zilola Farkhadovna. “MARKERS OF INFLAMMATION IN BRONCHIAL ASTHMA IN CHILDREN WITH CONSEQUENCES OF PERINATAL LESION TO THE CENTRAL NERVOUS SYSTEM.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(1) (2024). https://tadqiqot.uz/index.php/biomedicine/article/view/9249
HarvardKHAIDAROVA Sarvinoz Khaidarzhonovna, and MAVLYANOVA Zilola Farkhadovna (2024) ‘MARKERS OF INFLAMMATION IN BRONCHIAL ASTHMA IN CHILDREN WITH CONSEQUENCES OF PERINATAL LESION TO THE CENTRAL NERVOUS SYSTEM’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(1). https://tadqiqot.uz/index.php/biomedicine/article/view/9249
BibTeX
@article{khaidarovasarvinozkhaidarzhonovna2024,
  title = {MARKERS OF INFLAMMATION IN BRONCHIAL ASTHMA IN CHILDREN WITH CONSEQUENCES OF PERINATAL LESION TO THE CENTRAL NERVOUS SYSTEM},
  author = {KHAIDAROVA Sarvinoz Khaidarzhonovna and MAVLYANOVA Zilola Farkhadovna},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2024},
  volume = {9},
  number = {1},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/9249}
}

Boshqa maqola uchun iqtibos tayyorlash

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali jurnalidan boshqa maqolalar

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali — barcha maqolalar · 2024-yil arxivi

KHAIDAROVA Sarvinoz Khaidarzhonovna — boshqa maqolalari

Tibbiyot sohasidagi boshqa maqolalar

Tibbiyot sohasidagi OAK jurnallari