The preventive effect of calcium channel blockers at adjuvant-induced arthritis on the course of chronic arthritis, hematological blood parameters, as well as on the content of cytokines and C-reactive protein was studied in sexually mature male rats weighing 140-160 g. It has been established that calcium channel antagonists have an inhibitory effect on the development of adjuvant-induced arthritis, especially diltiazem and cinnarizine, which have an almost identical effect to diclofenac sodium. A more pronounced correction of violations of hematological parameters was observed in animals receiving prophylactic diltiazem. One of the mechanisms of the antiflagogenic action of calcium channel blockers is a decrease in the level of pro-inflammatory and an increase in anti-inflammatory interleukins.
| Mualliflar | KHAKIMOV Ziyaviddin Zaynutdinovich, RAKHMANOV Alisher Khudaiberdievich, BEKOVA Nodira Bahаdirovna |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashriyot | Тошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ |
| ISSN | 2181-9300 |
| Nashr sanasi | 2022-09-04 |
| Jild | 7 |
| Son | 4 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-27 |
адъювант индуцированный артрит, антагонисты кальциевых каналов, гематология, цитокины, adjuvant-induced arthritis, calcium channel antagonists, hematology, cytokines., адъювант билан чақирилган артрит, кальций канали антагонистлари, гематология, цитокинлар
| APA | KHAKIMOV Ziyaviddin Zaynutdinovich, RAKHMANOV Alisher Khudaiberdievich, & BEKOVA Nodira Bahаdirovna (2022). INFLUENCE OF CALCIUM CHANNEL ANTAGONISTS ON THE DEVELOPMENT OF ADJUVANT ARTHRITIS IN RATS.. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(4). https://tadqiqot.uz/index.php/biomedicine/article/view/5475 |
|---|---|
| GOST (OAK) | KHAKIMOV Ziyaviddin Zaynutdinovich, RAKHMANOV Alisher Khudaiberdievich, BEKOVA Nodira Bahаdirovna INFLUENCE OF CALCIUM CHANNEL ANTAGONISTS ON THE DEVELOPMENT OF ADJUVANT ARTHRITIS IN RATS. // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2022. – T. 7, № 4. |
| MLA | KHAKIMOV Ziyaviddin Zaynutdinovich, RAKHMANOV Alisher Khudaiberdievich, and BEKOVA Nodira Bahаdirovna. “INFLUENCE OF CALCIUM CHANNEL ANTAGONISTS ON THE DEVELOPMENT OF ADJUVANT ARTHRITIS IN RATS..” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(4), 2022. https://tadqiqot.uz/index.php/biomedicine/article/view/5475 |
| Chicago | KHAKIMOV Ziyaviddin Zaynutdinovich, RAKHMANOV Alisher Khudaiberdievich, and BEKOVA Nodira Bahаdirovna. “INFLUENCE OF CALCIUM CHANNEL ANTAGONISTS ON THE DEVELOPMENT OF ADJUVANT ARTHRITIS IN RATS..” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(4) (2022). https://tadqiqot.uz/index.php/biomedicine/article/view/5475 |
| Harvard | KHAKIMOV Ziyaviddin Zaynutdinovich, RAKHMANOV Alisher Khudaiberdievich, and BEKOVA Nodira Bahаdirovna (2022) ‘INFLUENCE OF CALCIUM CHANNEL ANTAGONISTS ON THE DEVELOPMENT OF ADJUVANT ARTHRITIS IN RATS.’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(4). https://tadqiqot.uz/index.php/biomedicine/article/view/5475 |
| BibTeX | @article{khakimovziyaviddinzaynutdinovich2022,
title = {INFLUENCE OF CALCIUM CHANNEL ANTAGONISTS ON THE DEVELOPMENT OF ADJUVANT ARTHRITIS IN RATS.},
author = {KHAKIMOV Ziyaviddin Zaynutdinovich and RAKHMANOV Alisher Khudaiberdievich and BEKOVA Nodira Bahаdirovna},
journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
year = {2022},
volume = {7},
number = {4},
url = {https://tadqiqot.uz/index.php/biomedicine/article/view/5475}
} |
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