Gossypol, a cotton cellulose derivative, like diclofenac sodium, inhibits the development of the inflammatory process in adjuvant-induced arthritis model in male white rats. The data of hematological studies and the level of C-reactive protein in the blood indicate a high pharmacological activity of gossypol, a derivative of cotton cellulose, which does not significantly differ from diclofenac sodium. It is believed that the restoration of the level of anti-inflammatory cytokines against the background of a acute decrease in pro-inflammatory cytokines has a great importance in the mechanism of the antiphlogogenic action of cotton cellulose derivative gossypol.
| Mualliflar | KHAKIMOV Ziyaviddin Zaynutdinovich, YULDASHEV Jurabek Isajanovich, RAKHMANOV Alisher Khudaiberdievich |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2022-04-08 |
| Jild | 7 |
| Son | 1 |
| Til | Rus |
адъювант индуцированный артрит, гематология, цитокины, целлюлоза, госсипол, adjuvant induced arthritis, hematology, cytokines, tsellyuloza, gossipol, адъювантли артрит,гематология, цитокинлар, целлюлоза, госсипол
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