Significance of polymorphism 66 a>g of the mtrr gene in the pathogenesis of dysplasia of the multilayer square epithelium of the cervic

SOLIEVA Ra’nokhon Bakhodir qizi, DAVLATOV Bakhodirjon Nabijonovich, ALIIEVA Dilfuza Abdullayeva, BOBOEV Qodirjon Tuhtaboyevich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2022-yil

Annotatsiya

We examined 100 women aged 25-49 years who initially applied to the scientific and consulting polyclinic of RSSPMC A&G MzRU divided into 2 subgroups: 53 patients with moderate severity and 47 women with moderate severity of cervical MPE dysplasia. The control group consists of 105 conditionally healthy women. As a result of the association analysis, a significant factor of polymorphism 66 A>G of the MTRR gene was identified as genetic factors predisposing to an increased risk of developing cervical MPE dysplasia. The revealed results indicate the presence of significant frequencies in the distribution of the allele frequency of the 66 A>G polymorphism of the MTRR gene in groups of patients with mild and moderate severity of cervical MPE and in the control sample. Data were obtained on the presence of the influence of the 66 A>G polymorphism of the MTRR gene on the development of cervical MPE dysplasia in women of reproductive age, which plays an important role in revealing the genetic structure and forming the mechanism of epithelial lesions of the cervix.

Maqola ma’lumotlari
MualliflarSOLIEVA Ra’nokhon Bakhodir qizi, DAVLATOV Bakhodirjon Nabijonovich, ALIIEVA Dilfuza Abdullayeva, BOBOEV Qodirjon Tuhtaboyevich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2022-04-08
Jild7
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

дисплазии многослойного плоского эпителия шейки матки; цервикальная интраэпителиальная неоплазия; рак шейки матки; полиморфизм 66 A>G гена MTRR., dysplasia of the stratified squamous epithelium of the cervix; cervical intraepithelial neoplasia; cervical cancer; polymorphism 66 A>G of the MTRR gene., бачадон бўйни кўп қаватли ясси епителийсининг дисплазияси; бачадон ичи неоплазияси; бачадон бўйни раки; МТRR генининг полиморфизми 66 A>G

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Tibbiyot

Iqtibos keltirish

APASOLIEVA Ra’nokhon Bakhodir qizi, DAVLATOV Bakhodirjon Nabijonovich, ALIIEVA Dilfuza Abdullayeva, & BOBOEV Qodirjon Tuhtaboyevich (2022). SIGNIFICANCE OF POLYMORPHISM 66 A>G OF THE MTRR GENE IN THE PATHOGENESIS OF DYSPLASIA OF THE MULTILAYER SQUARE EPITHELIUM OF THE CERVIC. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(1). https://tadqiqot.uz/index.php/biomedicine/article/view/4330
GOST (OAK)SOLIEVA Ra’nokhon Bakhodir qizi va b. SIGNIFICANCE OF POLYMORPHISM 66 A>G OF THE MTRR GENE IN THE PATHOGENESIS OF DYSPLASIA OF THE MULTILAYER SQUARE EPITHELIUM OF THE CERVIC // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2022. – T. 7, № 1.
MLASOLIEVA Ra’nokhon Bakhodir qizi, DAVLATOV Bakhodirjon Nabijonovich, ALIIEVA Dilfuza Abdullayeva, and BOBOEV Qodirjon Tuhtaboyevich. “SIGNIFICANCE OF POLYMORPHISM 66 A>G OF THE MTRR GENE IN THE PATHOGENESIS OF DYSPLASIA OF THE MULTILAYER SQUARE EPITHELIUM OF THE CERVIC.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(1), 2022. https://tadqiqot.uz/index.php/biomedicine/article/view/4330
ChicagoSOLIEVA Ra’nokhon Bakhodir qizi, DAVLATOV Bakhodirjon Nabijonovich, ALIIEVA Dilfuza Abdullayeva, and BOBOEV Qodirjon Tuhtaboyevich. “SIGNIFICANCE OF POLYMORPHISM 66 A>G OF THE MTRR GENE IN THE PATHOGENESIS OF DYSPLASIA OF THE MULTILAYER SQUARE EPITHELIUM OF THE CERVIC.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(1) (2022). https://tadqiqot.uz/index.php/biomedicine/article/view/4330
HarvardSOLIEVA Ra’nokhon Bakhodir qizi, DAVLATOV Bakhodirjon Nabijonovich, ALIIEVA Dilfuza Abdullayeva, and BOBOEV Qodirjon Tuhtaboyevich (2022) ‘SIGNIFICANCE OF POLYMORPHISM 66 A>G OF THE MTRR GENE IN THE PATHOGENESIS OF DYSPLASIA OF THE MULTILAYER SQUARE EPITHELIUM OF THE CERVIC’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(1). https://tadqiqot.uz/index.php/biomedicine/article/view/4330
BibTeX
@article{solievaranokhonbakhodirqizi2022,
  title = {SIGNIFICANCE OF POLYMORPHISM 66 A>G OF THE MTRR GENE IN THE PATHOGENESIS OF DYSPLASIA OF THE MULTILAYER SQUARE EPITHELIUM OF THE CERVIC},
  author = {SOLIEVA Ra’nokhon Bakhodir qizi and DAVLATOV Bakhodirjon Nabijonovich and ALIIEVA Dilfuza Abdullayeva and BOBOEV Qodirjon Tuhtaboyevich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2022},
  volume = {7},
  number = {1},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/4330}
}

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