Description of immunogistochemical changes in endometriosis

Karimjonov, Khomidjon, Mamataliyev , Avazbek, Каримжонов, Хомиджон, Маматалиев , Авазбек, Karimjonov, Xomidjon, Mamataliyev , Avazbek

Халқаро илмий педиатрия журнали · 2023-yil

Annotatsiya

In the study of the etio-pathogenesis of endometriosis, the study of the molecular-biological specificity of eutopic and ectopic endometrium - the expression of estrogen and progesterone receptors, proliferation, apoptosis, adhesion, angiogenesis, and cell invasion markers is one of the promising directions. The purpose of the work: to study the molecular-biological characteristics of adenomyosis and ovarian endometriosis in the proliferative phase of the menstrual cycle in women of reproductive age without other gynecological pathologies. Materials and methods: In this study, biopsies of premenopausal (18-51 years 60 biopsies) and postmenopausal women (age 51 and older, 20 biopsies) who underwent hysterectomy between 2019 and 2022 were examined by immunohistochemical methods. In this study, in 2019-22 AVPAB examined 80 adenomyosis and ovarian endometriosis biopsies, immunohistochemical examination of estrogen and progesterone hormonal activity disorders showed that in 60-90% of cases, progesterone, and in 50-70% of cases, estrogen hormone leads to the development of uterine adenomyosis and glandular hyperplasia of the uterus. atypical development of the endometrium and transition to a malignant tumor disease was observed. Ki-67 and p53 were shown in 20% of postmenopausal patients with the transition to the initial state of a low-grade tumor of the uterus.

Maqola ma’lumotlari
MualliflarKarimjonov, Khomidjon, Mamataliyev , Avazbek, Каримжонов, Хомиджон, Маматалиев , Авазбек, Karimjonov, Xomidjon, Mamataliyev , Avazbek
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2023-03-31
Jild2
Son3
Betlar121-127
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2023-2-3-121-127
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2023-2-3-121-127 · Maqolaning asl sahifasi

Kalit so‘zlar

эндометриоз, аденомиоз, эстрогены, прогестерон, К67, р53, иммуногистохимические исследования, endometriosis, adenomyosis, estrogen, progesterone, K67, r53, immunohistochemical tests, endometrioz, adenomioz, esterogen, progesteron, K67, r53, immunogistokimyoviy tekshirishlar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAKarimjonov, Khomidjon, Mamataliyev , Avazbek, Каримжонов, Хомиджон, Маматалиев , Авазбек, Karimjonov, Xomidjon, & Mamataliyev , Avazbek (2023). DESCRIPTION OF IMMUNOGISTOCHEMICAL CHANGES IN ENDOMETRIOSIS. Халқаро илмий педиатрия журнали, 2(3), 121-127. https://doi.org/10.56121/2181-2926-2023-2-3-121-127
GOST (OAK)Karimjonov, Khomidjon va b. DESCRIPTION OF IMMUNOGISTOCHEMICAL CHANGES IN ENDOMETRIOSIS // Халқаро илмий педиатрия журнали. – 2023. – T. 2, № 3. – P. 121-127. – DOI: 10.56121/2181-2926-2023-2-3-121-127.
MLAKarimjonov, Khomidjon, Mamataliyev , Avazbek, Каримжонов, Хомиджон, Маматалиев , Авазбек, Karimjonov, Xomidjon, and Mamataliyev , Avazbek. “DESCRIPTION OF IMMUNOGISTOCHEMICAL CHANGES IN ENDOMETRIOSIS.” Халқаро илмий педиатрия журнали, 2(3), 121-127, 2023. https://doi.org/10.56121/2181-2926-2023-2-3-121-127
ChicagoKarimjonov, Khomidjon, Mamataliyev , Avazbek, Каримжонов, Хомиджон, Маматалиев , Авазбек, Karimjonov, Xomidjon, and Mamataliyev , Avazbek. “DESCRIPTION OF IMMUNOGISTOCHEMICAL CHANGES IN ENDOMETRIOSIS.” Халқаро илмий педиатрия журнали, 2(3), 121-127 (2023). https://doi.org/10.56121/2181-2926-2023-2-3-121-127
HarvardKarimjonov, Khomidjon, Mamataliyev , Avazbek, Каримжонов, Хомиджон, Маматалиев , Авазбек, Karimjonov, Xomidjon, and Mamataliyev , Avazbek (2023) ‘DESCRIPTION OF IMMUNOGISTOCHEMICAL CHANGES IN ENDOMETRIOSIS’, Халқаро илмий педиатрия журнали, 2(3), 121-127. https://doi.org/10.56121/2181-2926-2023-2-3-121-127
BibTeX
@article{karimjonovkhomidjon2023,
  title = {DESCRIPTION OF IMMUNOGISTOCHEMICAL CHANGES IN ENDOMETRIOSIS},
  author = {Karimjonov, Khomidjon and Mamataliyev , Avazbek and Каримжонов, Хомиджон and Маматалиев , Авазбек and Karimjonov, Xomidjon and Mamataliyev , Avazbek},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2023},
  volume = {2},
  number = {3},
  pages = {121-127},
  doi = {10.56121/2181-2926-2023-2-3-121-127},
  url = {https://doi.org/10.56121/2181-2926-2023-2-3-121-127}
}

Boshqa maqola uchun iqtibos tayyorlash

Халқаро илмий педиатрия журнали jurnalidan boshqa maqolalar

Халқаро илмий педиатрия журнали — barcha maqolalar · 2023-yil arxivi

Karimjonov, Khomidjon — boshqa maqolalari

Tibbiyot sohasidagi boshqa maqolalar

Tibbiyot sohasidagi OAK jurnallari