Assessment of immunopathological developments in children with nephrotic syndrome with background pathology

Rakhmanova, Lola, Rakhmanov, Akramjon, Рахманова, Лола, Рахманов, Акрамжон, Rakhmanova, Lola, Rakhmanov , Akramjon

Халқаро илмий педиатрия журнали · 2022-yil

Annotatsiya

In order to assess immunopathological changes in children with nephrotic syndrome with underlying pathology, 120 children aged 7 to 11 years were examined. Of these: group 1 - 35 children with NS (nephrotic form of CGN); group 2 - 35 children with NS against the background of LD; group 3 - 25 children with LD. Healthy group: 25 practically healthy children of the same age. It was determined that in children with nephrotic syndrome (nephrotic form of chronic glomerulonephritis) occurring with underlying pathology (lymphatic diathesis), specific clinical symptoms are characteristic, such as increased edema (100.0%), oliguria (100.0%), "chalky" pallor (74.2%), anasarca (9.0%) and hepatosplenomegaly (57.1%), in parallel with this, the development of severe anemia, a decrease in cortisol, an increase in lymphocytosis, proteinuria, fibrinogen, gamma globulin and cholesterol, contributing to the development of steroid-dependent and steroid-resistant forms of the disease. In nephrotic syndrome with lymphatic diathesis, a deficiency of the cellular link of immunity, a violation of the production of the cytokine IL-2, an increase in the content of ABL-kidneys, ABL-lungs, which remain preserved even in the period of remission of the disease, are characteristic, which confirm that in the treatment of such contingents of patients it is necessary to include in therapy adequate methods of immunocorrection.

Maqola ma’lumotlari
MualliflarRakhmanova, Lola, Rakhmanov, Akramjon, Рахманова, Лола, Рахманов, Акрамжон, Rakhmanova, Lola, Rakhmanov , Akramjon
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2022-12-30
Jild1
Son8
Betlar11-17
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2022-8-11-17
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2022-8-11-17 · Maqolaning asl sahifasi

Kalit so‘zlar

лимфатический диатез, нефротический синдром, интерлейкин-2, иммунитет, lymphatic diathesis, nephrotic syndrome, interleukin-2, immunitу, limfa diatezi, nefrotik sindrom, interleykin-2, immunitet

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APARakhmanova, Lola, Rakhmanov, Akramjon, Рахманова, Лола, Рахманов, Акрамжон, Rakhmanova, Lola, & Rakhmanov , Akramjon (2022). ASSESSMENT OF IMMUNOPATHOLOGICAL DEVELOPMENTS IN CHILDREN WITH NEPHROTIC SYNDROME WITH BACKGROUND PATHOLOGY. Халқаро илмий педиатрия журнали, 1(8), 11-17. https://doi.org/10.56121/2181-2926-2022-8-11-17
GOST (OAK)Rakhmanova, Lola va b. ASSESSMENT OF IMMUNOPATHOLOGICAL DEVELOPMENTS IN CHILDREN WITH NEPHROTIC SYNDROME WITH BACKGROUND PATHOLOGY // Халқаро илмий педиатрия журнали. – 2022. – T. 1, № 8. – P. 11-17. – DOI: 10.56121/2181-2926-2022-8-11-17.
MLARakhmanova, Lola, Rakhmanov, Akramjon, Рахманова, Лола, Рахманов, Акрамжон, Rakhmanova, Lola, and Rakhmanov , Akramjon. “ASSESSMENT OF IMMUNOPATHOLOGICAL DEVELOPMENTS IN CHILDREN WITH NEPHROTIC SYNDROME WITH BACKGROUND PATHOLOGY.” Халқаро илмий педиатрия журнали, 1(8), 11-17, 2022. https://doi.org/10.56121/2181-2926-2022-8-11-17
ChicagoRakhmanova, Lola, Rakhmanov, Akramjon, Рахманова, Лола, Рахманов, Акрамжон, Rakhmanova, Lola, and Rakhmanov , Akramjon. “ASSESSMENT OF IMMUNOPATHOLOGICAL DEVELOPMENTS IN CHILDREN WITH NEPHROTIC SYNDROME WITH BACKGROUND PATHOLOGY.” Халқаро илмий педиатрия журнали, 1(8), 11-17 (2022). https://doi.org/10.56121/2181-2926-2022-8-11-17
HarvardRakhmanova, Lola, Rakhmanov, Akramjon, Рахманова, Лола, Рахманов, Акрамжон, Rakhmanova, Lola, and Rakhmanov , Akramjon (2022) ‘ASSESSMENT OF IMMUNOPATHOLOGICAL DEVELOPMENTS IN CHILDREN WITH NEPHROTIC SYNDROME WITH BACKGROUND PATHOLOGY’, Халқаро илмий педиатрия журнали, 1(8), 11-17. https://doi.org/10.56121/2181-2926-2022-8-11-17
BibTeX
@article{rakhmanovalola2022,
  title = {ASSESSMENT OF IMMUNOPATHOLOGICAL DEVELOPMENTS IN CHILDREN WITH NEPHROTIC SYNDROME WITH BACKGROUND PATHOLOGY},
  author = {Rakhmanova, Lola and Rakhmanov, Akramjon and Рахманова, Лола and Рахманов, Акрамжон and Rakhmanova, Lola and Rakhmanov , Akramjon},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2022},
  volume = {1},
  number = {8},
  pages = {11-17},
  doi = {10.56121/2181-2926-2022-8-11-17},
  url = {https://doi.org/10.56121/2181-2926-2022-8-11-17}
}

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