This article describes the results of the study and the characteristics of the cytokines IL-4, IL-18, IFN-γ and TNF-α in the blood plasma of HIV-positive and HIV-negative children. The study design was a cross-sectional study in which blood samples were collected from study subjects during ART. Cytokines IL-4, IL-18, TNF-α and INF-γ were determined using an ELISA kit (Vector Best, Russian Federation). The results showed the concentration of IFN-gamma, a regulator of the humoral immune response, in the group of patients with HIV infection was statistically significantly higher than in the control group (p=0.00001). On the contrary, the concentration of another regulator of the humoral immune response, IL-4, differs slightly in the main and control groups (p = 0.1425). The content of the pro-inflammatory cytokine TNF-alpha in the HIV-positive group was significantly higher than in the HIV-negative group (p = 0.00001). Also, the concentration of the pro-inflammatory cytokine IL-18 was significantly higher in the main group than in the control group (p=0.0002). Although cytokine profiles during antiretroviral therapy among people living with HIV (PLHIV) have been documented, no clearly defined pattern of effects of antiretroviral therapy on cytokine profiles has been identified.
| Mualliflar | Karimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, Azimov , Shovkat, Каримов, Дониёр, Ахмеджанова, Зульфия, Урунова, Дильбар, Эрматов, Ботир, Эргашев, Баходир, Меликузиев, Ойбек, Суннатова, Нигора, Азимов, Шовкат, Karimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, Azimov , Shovkat |
|---|---|
| Jurnal | Жамият ва инновациялар / Общество и инновации / Society and innovations |
| Nashr sanasi | 2024-03-25 |
| Jild | 5 |
| Son | 2 |
| Betlar | 151-156 |
| Til | Ingliz |
| DOI | 10.47689/2181-1415-vol5-iss2-pp151-156 |
DOI: 10.47689/2181-1415-vol5-iss2-pp151-156 · Maqolaning asl sahifasi
interleukins, HIV, CD4 cells, интерлейкины, ВИЧ, CD4 клетки, interleykinlar, OIV, CD4 hujayralari
This article examines the psychology of teaching foreign languages as a separate area within educational psychology. The importance of effective multilingual communication in the modern world is noted. It is emphasized…
This article is a study of the stage of family development, which is characterized by the most constructive and effective overcoming of normative difficulties. The authors draw attention to the achievement of a high…
The article discusses the theoretical foundations of the concept of innovation, which is currently one of the current topics, and the main direction of research is the concept of innovative economics. In addition, the…
The article analyzes empirical data on the characteristics of the manifestation of orientation towards professional activity in the system of personal needs. The direction of a person is understood as a network of…
In the article, the author, from the point of view of criminal law, examines the issues of signs of the subject of hooliganism. In particular, as an integral feature of the crime under study, the characteristics of the…
The family is a complex sociocultural phenomenon that ensures the economic, social, psychological, and physical security of its members. It covers almost all aspects of human life and manifests itself at all levels of…
The article discusses the use of solar energy as an alternative energy source using solar air heaters. To develop a method for calculating the thermal performance of such devices, the authors developed a model for…
The article analyzes the emergence of the organization of trade unions and its contradictory paths based on historical sources and materials from periodicals.
The rapid evolution of new innovation technologies, especially in the domain of artificial intelligence (AI), can lead to profound psychological impacts. This case study delves into the experiences of an individual…
The article describes the trade of the Bukhara Emirate with the Russian Empire in the second half of the XIX - early XX centuries, as well as the content of trade agreements concluded between the Russian and Bukhara…
Жамият ва инновациялар / Общество и инновации / Society and innovations — barcha maqolalar