Features of pro- and anti-inflammatory cytokines in the blood of HIV-positive children

Karimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, Azimov , Shovkat, Каримов, Дониёр, Ахмеджанова, Зульфия, Урунова, Дильбар, Эрматов, Ботир, Эргашев, Баходир, Меликузиев, Ойбек, Суннатова, Нигора, Азимов, Шовкат, Karimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, Azimov , Shovkat

Жамият ва инновациялар / Общество и инновации / Society and innovations · 2024-yil

Annotatsiya

This article describes the results of the study and the characteristics of the cytokines IL-4, IL-18, IFN-γ and TNF-α in the blood plasma of HIV-positive and HIV-negative children. The study design was a cross-sectional study in which blood samples were collected from study subjects during ART. Cytokines IL-4, IL-18, TNF-α and INF-γ were determined using an ELISA kit (Vector Best, Russian Federation). The results showed the concentration of IFN-gamma, a regulator of the humoral immune response, in the group of patients with HIV infection was statistically significantly higher than in the control group (p=0.00001). On the contrary, the concentration of another regulator of the humoral immune response, IL-4, differs slightly in the main and control groups (p = 0.1425). The content of the pro-inflammatory cytokine TNF-alpha in the HIV-positive group was significantly higher than in the HIV-negative group (p = 0.00001). Also, the concentration of the pro-inflammatory cytokine IL-18 was significantly higher in the main group than in the control group (p=0.0002). Although cytokine profiles during antiretroviral therapy among people living with HIV (PLHIV) have been documented, no clearly defined pattern of effects of antiretroviral therapy on cytokine profiles has been identified.

Maqola ma’lumotlari
MualliflarKarimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, Azimov , Shovkat, Каримов, Дониёр, Ахмеджанова, Зульфия, Урунова, Дильбар, Эрматов, Ботир, Эргашев, Баходир, Меликузиев, Ойбек, Суннатова, Нигора, Азимов, Шовкат, Karimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, Azimov , Shovkat
JurnalЖамият ва инновациялар / Общество и инновации / Society and innovations
NashriyotIn Science МЧЖ
ISSN2181-1415
Nashr sanasi2024-03-25
Jild5
Son2
Betlar151-156
TilIngliz
Ilmiy sohaTibbiyot
DOI10.47689/2181-1415-vol5-iss2-pp151-156
Indeksga qo‘shilgan2026-08-26

DOI: 10.47689/2181-1415-vol5-iss2-pp151-156 · Maqolaning asl sahifasi

Kalit so‘zlar

interleukins, HIV, CD4 cells, интерлейкины, ВИЧ, CD4 клетки, interleykinlar, OIV, CD4 hujayralari

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAKarimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, Azimov , Shovkat, Каримов, Дониёр, Ахмеджанова, Зульфия, Урунова, Дильбар, Эрматов, Ботир, Эргашев, Баходир, Меликузиев, Ойбек, Суннатова, Нигора, Азимов, Шовкат, Karimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, & Azimov , Shovkat (2024). Features of pro- and anti-inflammatory cytokines in the blood of HIV-positive children. Жамият ва инновациялар / Общество и инновации / Society and innovations, 5(2), 151-156. https://doi.org/10.47689/2181-1415-vol5-iss2-pp151-156
GOST (OAK)Karimov , Doniyor va b. Features of pro- and anti-inflammatory cytokines in the blood of HIV-positive children // Жамият ва инновациялар / Общество и инновации / Society and innovations. – 2024. – T. 5, № 2. – P. 151-156. – DOI: 10.47689/2181-1415-vol5-iss2-pp151-156.
MLAKarimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, Azimov , Shovkat, Каримов, Дониёр, Ахмеджанова, Зульфия, Урунова, Дильбар, Эрматов, Ботир, Эргашев, Баходир, Меликузиев, Ойбек, Суннатова, Нигора, Азимов, Шовкат, Karimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, and Azimov , Shovkat. “Features of pro- and anti-inflammatory cytokines in the blood of HIV-positive children.” Жамият ва инновациялар / Общество и инновации / Society and innovations, 5(2), 151-156, 2024. https://doi.org/10.47689/2181-1415-vol5-iss2-pp151-156
ChicagoKarimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, Azimov , Shovkat, Каримов, Дониёр, Ахмеджанова, Зульфия, Урунова, Дильбар, Эрматов, Ботир, Эргашев, Баходир, Меликузиев, Ойбек, Суннатова, Нигора, Азимов, Шовкат, Karimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, and Azimov , Shovkat. “Features of pro- and anti-inflammatory cytokines in the blood of HIV-positive children.” Жамият ва инновациялар / Общество и инновации / Society and innovations, 5(2), 151-156 (2024). https://doi.org/10.47689/2181-1415-vol5-iss2-pp151-156
HarvardKarimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, Azimov , Shovkat, Каримов, Дониёр, Ахмеджанова, Зульфия, Урунова, Дильбар, Эрматов, Ботир, Эргашев, Баходир, Меликузиев, Ойбек, Суннатова, Нигора, Азимов, Шовкат, Karimov , Doniyor, Akhmedjanova , Zulfiya, Urunova , Dilbar, Ermatov, Botir, Ergashev, Bakhodir, Melikuziev, Oybek, Sunnatova, Nigora, and Azimov , Shovkat (2024) ‘Features of pro- and anti-inflammatory cytokines in the blood of HIV-positive children’, Жамият ва инновациялар / Общество и инновации / Society and innovations, 5(2), 151-156. https://doi.org/10.47689/2181-1415-vol5-iss2-pp151-156
BibTeX
@article{karimovdoniyor2024,
  title = {Features of pro- and anti-inflammatory cytokines in the blood of HIV-positive children},
  author = {Karimov , Doniyor and Akhmedjanova , Zulfiya and Urunova , Dilbar and Ermatov, Botir and Ergashev, Bakhodir and Melikuziev, Oybek and Sunnatova, Nigora and Azimov , Shovkat and Каримов, Дониёр and Ахмеджанова, Зульфия and Урунова, Дильбар and Эрматов, Ботир and Эргашев, Баходир and Меликузиев, Ойбек and Суннатова, Нигора and Азимов, Шовкат and Karimov , Doniyor and Akhmedjanova , Zulfiya and Urunova , Dilbar and Ermatov, Botir and Ergashev, Bakhodir and Melikuziev, Oybek and Sunnatova, Nigora and Azimov , Shovkat},
  journal = {Жамият ва инновациялар / Общество и инновации / Society and innovations},
  year = {2024},
  volume = {5},
  number = {2},
  pages = {151-156},
  doi = {10.47689/2181-1415-vol5-iss2-pp151-156},
  url = {https://doi.org/10.47689/2181-1415-vol5-iss2-pp151-156}
}

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