Pathomorphological manifestations of impaired placental-fetal interaction in menstruation-associated iron deficiency anemia

Насирова Зебинисо Азизовна

Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2026-yil

Annotatsiya

Iron deficiency anemia (IDA) represents a significant global health issue affecting a considerable proportion of women of reproductive age, particularly more than 40% of pregnant women. Iron is essential not only for hematopoiesis but also plays a critical role in cellular respiration, functioning of enzyme systems, angiogenesis, and myelination of fetal neural tissue. The requirement for iron substantially increases during pregnancy, thereby heightening the risk of iron deficiency states, which may lead to placental insufficiency and complications during pregnancy. Particularly important is the investigation of pathomorphological changes in the mother-placenta-fetus system among women with menstruation-associated IDA due to chronic heavy menstrual bleeding (HMB). In our study, marked pathological alterations in the umbilical cord vessel structures were identified, characterized by ischemia, sclerosis, and disruptions in endothelial architecture, confirmed by light and electron microscopy. The endothelial cells demonstrated degenerative changes, loss of normal surface relief, and destructive processes, indicating significant metabolic and vascular perfusion disturbances. These morphological alterations significantly affect the functionality of the fetoplacental complex, highlighting an increased risk of fetoplacental insufficiency, intrauterine growth restriction, and other perinatal complications. The identified changes carry crucial prognostic implications and underscore the importance of timely diagnosis and correction of iron deficiency states in women of reproductive age.

Maqola ma’lumotlari
MualliflarНасирова Зебинисо Азизовна
JurnalJournal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)
NashriyotСамарқанд давлат тиббиёт университети
ISSN2017-2021
Nashr sanasi2026-05-25
Jild6
Son3
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

анемия, железодефицитная анемия, беременность, обильные менструации, аномальные маточные кровотечения, FIGO, плацентарная недостаточность, дефицит железа, здоровье матери и плода, anemia, iron deficiency anemia, pregnancy, heavy menstruation, abnormal uterine bleeding, FIGO, placental insufficiency, iron deficiency, maternal and fetal health, anemiya, temir tanqisligi anemiyasi, homiladorlik, ko‘p miqdordagi hayz ko‘rish, anormal bachadon qon ketishlari, FIGO, plasentar yetishmovchilik, temir tanqisligi, ona va homila salomatligi

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAНасирова Зебинисо Азизовна (2026). PATHOMORPHOLOGICAL MANIFESTATIONS OF IMPAIRED PLACENTAL-FETAL INTERACTION IN MENSTRUATION-ASSOCIATED IRON DEFICIENCY ANEMIA. Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 6(3). https://tadqiqot.uz/index.php/uro/article/view/13931
GOST (OAK)Насирова Зебинисо Азизовна PATHOMORPHOLOGICAL MANIFESTATIONS OF IMPAIRED PLACENTAL-FETAL INTERACTION IN MENSTRUATION-ASSOCIATED IRON DEFICIENCY ANEMIA // Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали). – 2026. – T. 6, № 3.
MLAНасирова Зебинисо Азизовна. “PATHOMORPHOLOGICAL MANIFESTATIONS OF IMPAIRED PLACENTAL-FETAL INTERACTION IN MENSTRUATION-ASSOCIATED IRON DEFICIENCY ANEMIA.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 6(3), 2026. https://tadqiqot.uz/index.php/uro/article/view/13931
ChicagoНасирова Зебинисо Азизовна. “PATHOMORPHOLOGICAL MANIFESTATIONS OF IMPAIRED PLACENTAL-FETAL INTERACTION IN MENSTRUATION-ASSOCIATED IRON DEFICIENCY ANEMIA.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 6(3) (2026). https://tadqiqot.uz/index.php/uro/article/view/13931
HarvardНасирова Зебинисо Азизовна (2026) ‘PATHOMORPHOLOGICAL MANIFESTATIONS OF IMPAIRED PLACENTAL-FETAL INTERACTION IN MENSTRUATION-ASSOCIATED IRON DEFICIENCY ANEMIA’, Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 6(3). https://tadqiqot.uz/index.php/uro/article/view/13931
BibTeX
@article{article2026,
  title = {PATHOMORPHOLOGICAL MANIFESTATIONS OF IMPAIRED PLACENTAL-FETAL INTERACTION IN MENSTRUATION-ASSOCIATED IRON DEFICIENCY ANEMIA},
  author = {Насирова Зебинисо Азизовна},
  journal = {Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)},
  year = {2026},
  volume = {6},
  number = {3},
  url = {https://tadqiqot.uz/index.php/uro/article/view/13931}
}

Boshqa maqola uchun iqtibos tayyorlash

Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) jurnalidan boshqa maqolalar

Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) — barcha maqolalar · 2026-yil arxivi

Насирова Зебинисо Азизовна — boshqa maqolalari

Tibbiyot sohasidagi boshqa maqolalar

Tibbiyot sohasidagi OAK jurnallari