In this article, coumarins isolated from the plants Haplophyllum obtusifolium and Haplophyllum perforatum were studied, and it was found that obtusinin is less toxic and has a pronounced sedative effect. The mechanism of anticonvulsant action of obtusinin is associated with antagonism to nicotine-sensitive receptors, a decrease in the activity of the cholinergic system and, possibly, an increase in the activity of the GAMK system.
| Mualliflar | Saloxiddin Aminov |
|---|---|
| Jurnal | Фармация ва фармакология |
| Nashr sanasi | 2026-04-20 |
| Jild | 1 |
| Son | 15 |
| Betlar | 107-112 |
| DOI | 10.66657/phcc/vol1_iss6-15/art14 |
DOI: 10.66657/phcc/vol1_iss6-15/art14 · Maqolaning asl sahifasi
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