Genetic polymorphisms of the prl and prlr genes in patients with breast cancer and hyperprolactinemia

Z.Yu. Khalimova, А.А. ГУМАРОВА

Zamonaviy tibbiyot jurnali / Journal of modern medicine · 2026-yil

Annotatsiya

Despite the accumulated evidence regarding the role of hyperprolactinemia (HPRL) in the pathogenesis of breast cancer (BC), the genetic determinants of this condition remain insufficiently investigated. Single nucleotide polymorphisms (SNPs) in the PRL and PRLR genes may influence the regulation of prolactin-dependent signaling pathways by altering prolactin expression, the functional activity of its receptor, and the characteristics of intercellular signal transduction. Consequently, these genetic variants may contribute to differences in tumor progression, patients’ hormonal status, and response to anticancer therapy.

Maqola ma’lumotlari
MualliflarZ.Yu. Khalimova, А.А. ГУМАРОВА
JurnalZamonaviy tibbiyot jurnali / Journal of modern medicine
NashriyotАндижон давлат тиббиёт институти
ISSN2992-8958
Nashr sanasi2026-07-08
Jild14
Son3
Betlar95-98
TilIngliz
Ilmiy sohaTibbiyot
DOI10.67519/nshr.ztj.2026.03.023
Indeksga qo‘shilgan2026-09-02

Ilmiy soha

Iqtibos keltirish

APAZ.Yu. Khalimova, & А.А. ГУМАРОВА (2026). GENETIC POLYMORPHISMS OF THE PRL AND PRLR GENES IN PATIENTS WITH BREAST CANCER AND HYPERPROLACTINEMIA. Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 95-98. https://doi.org/10.67519/nshr.ztj.2026.03.023
GOST (OAK)Z.Yu. Khalimova, А.А. ГУМАРОВА GENETIC POLYMORPHISMS OF THE PRL AND PRLR GENES IN PATIENTS WITH BREAST CANCER AND HYPERPROLACTINEMIA // Zamonaviy tibbiyot jurnali / Journal of modern medicine. – 2026. – T. 14, № 3. – P. 95-98. – DOI: 10.67519/nshr.ztj.2026.03.023.
MLAZ.Yu. Khalimova, and А.А. ГУМАРОВА. “GENETIC POLYMORPHISMS OF THE PRL AND PRLR GENES IN PATIENTS WITH BREAST CANCER AND HYPERPROLACTINEMIA.” Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 95-98, 2026. https://doi.org/10.67519/nshr.ztj.2026.03.023
ChicagoZ.Yu. Khalimova, and А.А. ГУМАРОВА. “GENETIC POLYMORPHISMS OF THE PRL AND PRLR GENES IN PATIENTS WITH BREAST CANCER AND HYPERPROLACTINEMIA.” Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 95-98 (2026). https://doi.org/10.67519/nshr.ztj.2026.03.023
HarvardZ.Yu. Khalimova, and А.А. ГУМАРОВА (2026) ‘GENETIC POLYMORPHISMS OF THE PRL AND PRLR GENES IN PATIENTS WITH BREAST CANCER AND HYPERPROLACTINEMIA’, Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 95-98. https://doi.org/10.67519/nshr.ztj.2026.03.023
BibTeX
@article{zyukhalimova2026,
  title = {GENETIC POLYMORPHISMS OF THE PRL AND PRLR GENES IN PATIENTS WITH BREAST CANCER AND HYPERPROLACTINEMIA},
  author = {Z.Yu. Khalimova and А.А. ГУМАРОВА},
  journal = {Zamonaviy tibbiyot jurnali / Journal of modern medicine},
  year = {2026},
  volume = {14},
  number = {3},
  pages = {95-98},
  doi = {10.67519/nshr.ztj.2026.03.023},
  url = {https://doi.org/10.67519/nshr.ztj.2026.03.023}
}

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