CLINICAL AND PROGNOSTIC SIGNIFICANCE OF C-REACTIVE PROTEIN DYNAMICS AFTER PERCUTANEOUS CORONARY INTERVENTION

J. Kh. Tursunov

Zamonaviy tibbiyot jurnali / Journal of modern medicine · 2026-yil

Annotatsiya

The aim of this study was to evaluate the dynamics of C-reactive protein (CRP) levels in patients with ischemic heart disease following percutaneous coronary intervention (PCI) and to determine its prognostic value for in-stent restenosis, stent thrombosis, and major adverse cardiovascular events (MACE). A total of 102 patients who underwent PCI were prospectively enrolled in the study. CRP levels were measured before the procedure and at 24 hours, 1 month, 3 months, 6 months, and 9 months after the intervention. During the follow-up period, the incidence of in-stent restenosis, stent thrombosis, and MACE was evaluated. The results demonstrated that CRP reached its peak within the first 24 hours after PCI and subsequently showed a gradual decline throughout the follow-up period. Persistently elevated CRP levels were significantly associated with an increased risk of in-stent restenosis, stent throm­bosis, and MACE (p<0.05). These findings indicate that CRP is an important prognostic biomarker in patients after PCI. Dynamic monitoring of CRP may facilitate early identification of high-risk patients, support individualized clinical follow-up, and improve the prediction of adverse cardiovascular outcomes.

Maqola ma’lumotlari
MualliflarJ. Kh. Tursunov
JurnalZamonaviy tibbiyot jurnali / Journal of modern medicine
Nashr sanasi2026-07-02
Jild14
Son3
Betlar11-18
Tilen
DOI10.67519/nshr.ztj.2026.03.002

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