Annotation. Epilepsy remains one of the leading chronic pathologies of the brain, affecting more than 70 million people in the world. Epilepsy is associated with an increased risk of morbidity, comorbidity and mortality, and seriously affects the quality of life of patients. Although antiseizure drug therapy is effective in preventing seizures in most cases of epilepsy, some people with epilepsy never achieve seizure control. Studies have shown that 60–70% of patients with epilepsy respond to treatment, while 30–40% become resistant to antiseizure drug treatment. This review article examines modern hypotheses for the occurrence of drug-resistant epilepsy. A list of studied and identified genetic changes that are detected in drug-resistant conditions is also provided. The article provides data on the prevalence of drug-resistant epilepsy, features of diagnosis and treatment of patients with this pathology.
| Mualliflar | Т. Ш. Нишонов, Н. М. Туйчибаева, Алимходжаева П.Р., Ганиев Б.Б. |
|---|---|
| Jurnal | Передовая Офтальмология |
| Nashr sanasi | 2023-11-28 |
| Jild | 5 |
| Son | 5 |
| Betlar | 38-42 |
| Til | ru |
| DOI | 10.57231/j.ao.2023.5.5.007 |
DOI: 10.57231/j.ao.2023.5.5.007 · Maqolaning asl sahifasi · PDF
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