Relevance. With the introduction of OCT devices into modern ophthalmology with a tunable radiation source, the SWEEP Source, it became possible to perform accurate measurements of the thickness of the choroid and qualitatively visualize its structure. Purpose of the study. The aim of the research to evaluate the effectiveness of the angiogenesis inhibitor Aflibercept in the treatment of choroidal neovascularization (CNV) using the method of Swift Source OCT angiography Type I, developed in pachychoroidal diseases. Material and methods. The study included 37 patients (37 eyes) with pachychoroidal diseases complicated by type I CNV. All patients received intravitreal injections of Aflibercept using standard technology. The effectiveness of antiangiogenic therapy was evaluated based on the results of spectral Sweep Source OCT with angiography mode. Morphological signs of CNV «activity» were evaluated using the Coscas G. J. (2015) method. The follow-up period was 18 months. Results and conclusions. The method of SWEEP Source OCT with angiography mode revealed specific patterns of «activity» of CNV. After intravitreal administration of Aflibercept, the area of the neovascular membrane decreased by an average of 0.622+0.07 mm2 (from 0.939 ± 0.06 mm2 to 0.424 ± 0.08 mm2) in 34 eyes (89.5%), did not change in 3 eyes (10.5%). According to OCT angiography, the dynamics of the patterns of «activity» of CNV tended to fade in all cases. Sweep Source OCT with angiography mode is a highly informative method for monitoring morphological and morphometric changes in the «activity» of choroidal neovascularization, which allows the method to be used in evaluating the effectiveness of anti-VEGF therapy in pachychoroidal diseases complicated by type I choroidal neovascularization.
| Mualliflar | Н. А. Усманова |
|---|---|
| Jurnal | Передовая Офтальмология |
| Nashr sanasi | 2024-06-08 |
| Jild | 8 |
| Son | 2 |
| Betlar | 102-106 |
| Til | ru |
| DOI | 10.57231/j.ao.2024.8.2.020 |
DOI: 10.57231/j.ao.2024.8.2.020 · Maqolaning asl sahifasi
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