Quinazoline derivatives are important heterocyclic compounds with significant roles in organic synthesis and drug design, with 4-aminoquinazoline derivatives being particularly noteworthy due to their biological activity. In this study, the key precursor N-(4-(((7-nitroquinazolin-4-yl)amino)methyl)phenyl)cyclohexanecarboxamide was successfully synthesized in high yield and with operational simplicity. The structure and purity of the synthesized compound were confirmed by 1H NMR, 13C NMR, and HRMS, highlighting its potential as a versatile scaffold for further medicinal and biological investigations.
| Mualliflar | Sh. Gaybullaev, Y. Takhirov, Chao Niu, Kh. Bozorov |
|---|---|
| Jurnal | Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi |
| Nashriyot | Самарқанд давлат университети |
| ISSN | 2091-5446, 2181-1296 |
| Nashr sanasi | 2026-01-01 |
| Jild | 1 |
| Son | 2 |
| Betlar | 37-41 |
| Til | Ingliz |
| Ilmiy soha | Kimyo |
| DOI | 10.59251/2181-3973.2025.v1.138.1.3746 |
| Indeksga qo‘shilgan | 2026-09-02 |
DOI: 10.59251/2181-3973.2025.v1.138.1.3746 · Maqolaning asl sahifasi
| APA | Sh. Gaybullaev, Y. Takhirov, Chao Niu, & Kh. Bozorov (2026). SYNTHESIS OF N-(4-(((7-NITROQUINAZOLIN-4-YL)AMINO)METHYL)PHENYL)CYCLOHEXANECARBOXAMIDE. Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(2), 37-41. https://doi.org/10.59251/2181-3973.2025.v1.138.1.3746 |
|---|---|
| GOST (OAK) | Sh. Gaybullaev va b. SYNTHESIS OF N-(4-(((7-NITROQUINAZOLIN-4-YL)AMINO)METHYL)PHENYL)CYCLOHEXANECARBOXAMIDE // Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi. – 2026. – T. 1, № 2. – P. 37-41. – DOI: 10.59251/2181-3973.2025.v1.138.1.3746. |
| MLA | Sh. Gaybullaev, Y. Takhirov, Chao Niu, and Kh. Bozorov. “SYNTHESIS OF N-(4-(((7-NITROQUINAZOLIN-4-YL)AMINO)METHYL)PHENYL)CYCLOHEXANECARBOXAMIDE.” Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(2), 37-41, 2026. https://doi.org/10.59251/2181-3973.2025.v1.138.1.3746 |
| Chicago | Sh. Gaybullaev, Y. Takhirov, Chao Niu, and Kh. Bozorov. “SYNTHESIS OF N-(4-(((7-NITROQUINAZOLIN-4-YL)AMINO)METHYL)PHENYL)CYCLOHEXANECARBOXAMIDE.” Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(2), 37-41 (2026). https://doi.org/10.59251/2181-3973.2025.v1.138.1.3746 |
| Harvard | Sh. Gaybullaev, Y. Takhirov, Chao Niu, and Kh. Bozorov (2026) ‘SYNTHESIS OF N-(4-(((7-NITROQUINAZOLIN-4-YL)AMINO)METHYL)PHENYL)CYCLOHEXANECARBOXAMIDE’, Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(2), 37-41. https://doi.org/10.59251/2181-3973.2025.v1.138.1.3746 |
| BibTeX | @article{shgaybullaev2026,
title = {SYNTHESIS OF N-(4-(((7-NITROQUINAZOLIN-4-YL)AMINO)METHYL)PHENYL)CYCLOHEXANECARBOXAMIDE},
author = {Sh. Gaybullaev and Y. Takhirov and Chao Niu and Kh. Bozorov},
journal = {Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi},
year = {2026},
volume = {1},
number = {2},
pages = {37-41},
doi = {10.59251/2181-3973.2025.v1.138.1.3746},
url = {https://doi.org/10.59251/2181-3973.2025.v1.138.1.3746}
} |
Boshqa maqola uchun iqtibos tayyorlash
Maqolada axborot texnologiyalari yordamida amalga oshirilgan yangi aloqa turi boʻlib, ommaviy axborot vositalarining madaniyat, axloq, ong va inson xatti-harakatlariga ta'sir qilish imkoniyatlarini tubdan…
In this study, activated carbon samples derived from walnut shells and chemically activated using H₃PO₄, KOH, and ZnCl₂ were comparatively evaluated in terms of their morphological features, pore development, and…
Ushbu ishda chegaraviy bosim gradientini hisobga olib birjinsli suyuqliklar anomal sizishining tekis-radial masalasi ko'rib chiqilgan. Jarayon kasr tartibli differentsial tenglama bilan modellashtirilgan. Kasr hosila…
Ancient Eastern and Western philosophy is the prelude to scientific and spiritual development of mankind. Regardless of the uniqueness and uniqueness of their development, they have some common laws. Philosophical…
This study analysed the luminescence spectra of zinc oxide (ZnO) and zinc selenide (ZnSe) micropowders obtained by single- and two-photon excitation with pulsed laser radiation on copper vapour. The mechanisms of…
Ushbu tadqiqot qarindoshlar nikohining tarixiy paydo po'lishi, uning antropologik ildizlari va ijtimoiy evolyutsiyasini o'rganishga qaratilgan. Tadqiqotda ijtimoiy jamiyatda qarindoshlik tizimi, endogamiya va ekzogamiya…
In this study, a g-CN-VN/CoNi2S4 nanocomposite material with a layer-by-layer architecture was successfully synthesized to improve the photocatalytic conversion efficiency of CO2. The material consists of a…
Maqolada buyuk mutafakkir, tabib va entsiklopedist Аbu Ali ibn Sinoning siyosiy qarashlari tahlil qilinadi. Muallif Ibn Sinoning jamiyat, davlat, qonun, adolat va davlat rahbari shaxsiyatiga oid g'oyalarini ochib…
This article analyses and studies the scientific experience of countries with developed important agricultural and agro-industrial sectors. Many proposals and recommendations have been developed for utilising these…
Ushbu maqolada ta'lim jarayonida innovatsion yondashuvlarni joriy etish va ularning samaradorligini baholash masalalari tahlil qilingan. Zamonaviy ta'lim tizimida interfaol usullar, axborot-kommunikatsiya…
Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi — barcha maqolalar · 2026-yil arxivi
Публикация посвящена разработке новых методических решений для оценки конкурентоспособности аптечных организаций на фоне стремительных изменений фармацевтического рынка. В качестве примера рассмотрен рынок Самаркандской…
Janus kinases (JAKs) are recognized as important molecular targets in targeted therapy, and their inhibitors are widely used for the treatment of various autoimmune and inflammatory diseases. Although several JAK…
In the present study, a series of tetracyclic thieno[3,2-d]pyrimidin derivatives were subjected to molecular docking simulations to evaluate their binding affinity toward the cyclooxygenase-2 (COX-2) active site…
This article examines the geometric modeling of Islamic decorative patterns and digital algorithms for their creation. The compositional structure of Islamic patterns, the laws of symmetry, repeating elements, and the…
Целью данного исследования явилось выявление факторов риска, а также клинических, лабораторных и инструментальных особенностей гипоксически-ишемических поражений центральной нервной системы (ЦНС) у новорожденных. В…
Relevance: Spinal cord injury (SCI) is a life-changing event accompanied not only by severe physical but also by profound psychological consequences. The incidence of depression and anxiety disorders in this category of…
Ushbu maqolada ingliz tilini xorijiy til sifatida o‘rganishda yangi so‘zlarni vizual va verbal usullar orqali o‘zlashtirish samaradorligi tahlil qilinadi. Tadqiqotda vizual materiallar (rasmlar, grafik tasvirlar va…
Ushbu maqolada mashina tarjimasi (MT) vositalarining Toshkent Kimyo xalqaro universitetida tahsil olayotgan o‘zbek-ingliz ikki tilli talabalarning ingliz tilidagi yozma ishlarida uchraydigan xatolarga ta’siri…
Maqolada 1892-yilda “Туркестанские ведомости” gazetasida chop etilgan Sattorxon Abdulg'afforovning “Qo'qon xonligining ruslar tomonidan istilo etilishidan oldingi ichki ahvoli haqida qisqacha ocherk” asarining…
This article examines the linguistic units and metaphorical fields that structure English ecological discourse — the texts that construct public understanding of nature and environmental crisis. Drawing on Conceptual…
Maqolada 1929–1930-yillardan boshlab O‘zbekiston SSRda amalga oshirilgan yalpi kollektivlashtirish, “quloqlarni sinf sifatida tugatish” siyosati va majburiy surgunning mahalliy jamiyat hayotiga ta’siri Farg‘ona vodiysi…
Amudaryo quyi oqimidagi sugʻoriladigan hududlarda qishloq xoʻjaligi qurgʻoqchiligini asosan yogʻin emas, balki daryodan olinadigan suv hajmi belgilaydi. Tadqiqotda Xorazm viloyatida bir yillik (2000, 2008, 2011) va…