Characteristics of changes in immune system indicators in thyroid gland diseases

Narziev Sherali Mukhammadovich, Nuraliev Nekkadam Abdullaevich

Klinik fanlar yilnomasi · 2026-yil

Annotatsiya

Relevance. Comparative studies of humoral immunity and the cytokine status of the immune system in various thyroid diseases and the study of the relationships between them have not been conducted sufficiently, and those that exist are scattered. Purpose. To determine humoral immunity and cytokine status in thyroid diseases, as well as to assess the relationship between them. Material and methods. Humoral immunity indices in patients' blood serum were determined by ELISA - IgA, IgM, IgG, IgE, IL-1β, TNF-α, IL-4, IL-10 and AB to TPO. Results. It was found that these patients had a tendency to increase serum IgA, IgM, IgG and IgE compared to healthy individuals, but the intensity of changes was different. IL-1β and TNF-α were significantly higher in patients than in healthy individuals, by 5.12 and 6.03 times, respectively, and the tendency and intensity of their increase were similar. The amount of AB to TPO in patients was 21.41 times higher than in healthy individuals. Positive, direct, but varying strength correlations were found between serum immunoglobulins, cytokines and AB to TPO.

Maqola ma’lumotlari
MualliflarNarziev Sherali Mukhammadovich, Nuraliev Nekkadam Abdullaevich
JurnalKlinik fanlar yilnomasi
NashriyotБухоро давлат тиббиёт институти
ISSN2025-2026, 0009-0006
Nashr sanasi2026-04-13
Jild2
Son4/2
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

thyroid diseases, humoral immunity, immunoglobulins, cytokines, AB to TPO., заболевания щитовидной железы, гуморальный иммунитет, иммуноглобулины, цитокины, аутоантитела к ТПО., қалқонсимон без касалликлари, гуморал иммунитет, иммуноглобулинлар, цитокинлар, ТПО га қарши аутоантителолар.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APANarziev Sherali Mukhammadovich, & Nuraliev Nekkadam Abdullaevich (2026). CHARACTERISTICS OF CHANGES IN IMMUNE SYSTEM INDICATORS IN THYROID GLAND DISEASES. Klinik fanlar yilnomasi, 2(4/2). https://tadqiqot.uz/index.php/spjacd/article/view/13419
GOST (OAK)Narziev Sherali Mukhammadovich, Nuraliev Nekkadam Abdullaevich CHARACTERISTICS OF CHANGES IN IMMUNE SYSTEM INDICATORS IN THYROID GLAND DISEASES // Klinik fanlar yilnomasi. – 2026. – T. 2, № 4/2.
MLANarziev Sherali Mukhammadovich, and Nuraliev Nekkadam Abdullaevich. “CHARACTERISTICS OF CHANGES IN IMMUNE SYSTEM INDICATORS IN THYROID GLAND DISEASES.” Klinik fanlar yilnomasi, 2(4/2), 2026. https://tadqiqot.uz/index.php/spjacd/article/view/13419
ChicagoNarziev Sherali Mukhammadovich, and Nuraliev Nekkadam Abdullaevich. “CHARACTERISTICS OF CHANGES IN IMMUNE SYSTEM INDICATORS IN THYROID GLAND DISEASES.” Klinik fanlar yilnomasi, 2(4/2) (2026). https://tadqiqot.uz/index.php/spjacd/article/view/13419
HarvardNarziev Sherali Mukhammadovich, and Nuraliev Nekkadam Abdullaevich (2026) ‘CHARACTERISTICS OF CHANGES IN IMMUNE SYSTEM INDICATORS IN THYROID GLAND DISEASES’, Klinik fanlar yilnomasi, 2(4/2). https://tadqiqot.uz/index.php/spjacd/article/view/13419
BibTeX
@article{narzievsheralimukhammadovich2026,
  title = {CHARACTERISTICS OF CHANGES IN IMMUNE SYSTEM INDICATORS IN THYROID GLAND DISEASES},
  author = {Narziev Sherali Mukhammadovich and Nuraliev Nekkadam Abdullaevich},
  journal = {Klinik fanlar yilnomasi},
  year = {2026},
  volume = {2},
  number = {4/2},
  url = {https://tadqiqot.uz/index.php/spjacd/article/view/13419}
}

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