This article presents the results of a clinical observation aimed at studying the response of local immunemechanisms in the oral cavity of patients undergoing orthodontic treatment using fixed orthodontic appliances. A total of147 patients aged 21–29 years were examined. Unstimulated oral fluid was used as the study material, in which lysozymeactivity, secretory immunoglobulin A levels, and interleukin-1β and interleukin-4 concentrations were determined. Theresults demonstrated that fixation of orthodontic appliances is accompanied by changes in the immunological profileof oral fluid, reflecting the development of an adaptive inflammatory response. The application of extended preventivemeasures contributes to a more favorable course of the adaptation period and promotes restoration of local immunebalance.
| Mualliflar | Rakhimberdiev , Rustam, Saifulaeva , Aziza |
|---|---|
| Jurnal | Innovation science and technologiy |
| Nashr sanasi | 2026-01-01 |
| Jild | 2 |
| Son | 1 |
| Til | Ingliz |
| DOI | 10.5281/zenodo.18277908 |
DOI: 10.5281/zenodo.18277908 · Maqolaning asl sahifasi
orthodontic treatment, oral fluid, local immunity, immunological parameters, inflammation.
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