Psychosomatic aspects of neurological and psychoemotional changes in women with precancerous uterine diseases

Ibadullaeva Noila Makhmudovna

Klinik fanlar yilnomasi · 2025-yil

Annotatsiya

The role of psychological factors in the pathogenesis of precancerous diseases of the reproductive system remains underexplored. The aim of the study was a comparative assessment of the psychoemotional state and biological markers of stress in women with two diseases of different etiologies: human papillomavirus (HPV)-associated cervical intraepithelial neoplasia (CIN, n=38) and endometrial hyperplasia (EH, n=32) associated with hormonal imbalance. Compared to the control group (n=40), both main groups showed significantly higher levels of anxiety and depression on the HADS scale (p<0.001). This psychological distress correlated with a disturbed diurnal profile of the stress hormone cortisol and changes in brain activity on EEG. Regardless of the disease's cause, a "precancerous" diagnosis triggers universal psychosomatic processes. These processes, in turn, are a significant pathogenetic factor that may negatively affect the function of the immune (in the case of CIN) and hormonal (in the case of EH) systems.

Maqola ma’lumotlari
MualliflarIbadullaeva Noila Makhmudovna
JurnalKlinik fanlar yilnomasi
NashriyotБухоро давлат тиббиёт институти
ISSN2025-2026, 0009-0006
Nashr sanasi2025-10-30
Jild2
Son3/1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Kalit so‘zlar

precancerous diseases, CIN, endometrial hyperplasia, psychosomatics, psychoneuroimmunology, stress, cortisol, EEG, immune response, hormonal imbalance., предраковые заболевания, ЦИН, гиперплазия эндометрия, психосоматика, психонейроиммунология, стресс, кортизол, ЭЭГ, иммунный ответ, гормональный дисбаланс., precancerous diseases, CIN, endometrial hyperplasia, psychosomatics, psychoneuroimmunology, stress, cortisol, EEG, immune response, hormonal imbalance.

Ilmiy soha

Iqtibos keltirish

APAIbadullaeva Noila Makhmudovna (2025). PSYCHOSOMATIC ASPECTS OF NEUROLOGICAL AND PSYCHOEMOTIONAL CHANGES IN WOMEN WITH PRECANCEROUS UTERINE DISEASES. Klinik fanlar yilnomasi, 2(3/1). https://tadqiqot.uz/index.php/spjacd/article/view/12639
GOST (OAK)Ibadullaeva Noila Makhmudovna PSYCHOSOMATIC ASPECTS OF NEUROLOGICAL AND PSYCHOEMOTIONAL CHANGES IN WOMEN WITH PRECANCEROUS UTERINE DISEASES // Klinik fanlar yilnomasi. – 2025. – T. 2, № 3/1.
MLAIbadullaeva Noila Makhmudovna. “PSYCHOSOMATIC ASPECTS OF NEUROLOGICAL AND PSYCHOEMOTIONAL CHANGES IN WOMEN WITH PRECANCEROUS UTERINE DISEASES.” Klinik fanlar yilnomasi, 2(3/1), 2025. https://tadqiqot.uz/index.php/spjacd/article/view/12639
ChicagoIbadullaeva Noila Makhmudovna. “PSYCHOSOMATIC ASPECTS OF NEUROLOGICAL AND PSYCHOEMOTIONAL CHANGES IN WOMEN WITH PRECANCEROUS UTERINE DISEASES.” Klinik fanlar yilnomasi, 2(3/1) (2025). https://tadqiqot.uz/index.php/spjacd/article/view/12639
HarvardIbadullaeva Noila Makhmudovna (2025) ‘PSYCHOSOMATIC ASPECTS OF NEUROLOGICAL AND PSYCHOEMOTIONAL CHANGES IN WOMEN WITH PRECANCEROUS UTERINE DISEASES’, Klinik fanlar yilnomasi, 2(3/1). https://tadqiqot.uz/index.php/spjacd/article/view/12639
BibTeX
@article{ibadullaevanoilamakhmudovna2025,
  title = {PSYCHOSOMATIC ASPECTS OF NEUROLOGICAL AND PSYCHOEMOTIONAL CHANGES IN WOMEN WITH PRECANCEROUS UTERINE DISEASES},
  author = {Ibadullaeva Noila Makhmudovna},
  journal = {Klinik fanlar yilnomasi},
  year = {2025},
  volume = {2},
  number = {3/1},
  url = {https://tadqiqot.uz/index.php/spjacd/article/view/12639}
}

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