Burn disease causes a systemic inflammatory response and multiple organ dysfunction, primarily affecting the liver as the central organ of metabolic and detoxification regulation. This article discusses the main pathogenetic mechanisms of liver damage in burns, including ischemia, cytokine storm, oxidative stress and metabolic overload. Biochemical and ultrasound markers of hepatocellular and cholestatic syndromes reflecting the severity of the lesion are summarized. Based on the data of domestic and international studies, modern approaches to diagnostics and therapy of liver dysfunction are discussed, including the use of hepatoprotectors, detoxification techniques and microcirculation monitoring. The findings emphasize the need for systemic monitoring of liver function in the management of patients with burn injury and the relevance of integrating liver parameters into intensive care standards.
| Mualliflar | Barnoyev S.Sh |
|---|---|
| Jurnal | Klinik fanlar yilnomasi |
| Nashriyot | Бухоро давлат тиббиёт институти |
| ISSN | 2025-2026, 0009-0006 |
| Nashr sanasi | 2025-08-12 |
| Jild | 2 |
| Son | 1 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-26 |
burn disease, liver, hepatoprotection, bilirubin, cytokines, transaminases, detoxification, hypoperfusion, ожоговая болезнь, печень, гепатопротекция, билирубин, цитокины, трансаминазы, детоксикация, гипоперфузия, kuyish kasalligi, jigar, gepatoproteksiya, bilirubin, sitokinlar, transaminazalar, detoksifikatsiya, gipoperfuziya
| APA | Barnoyev S.Sh (2025). LIVER CONDITION IN BURN DISEASE PATHOGENETIC MECHANISMS, CLINICAL MANIFESTATIONS AND APPROACHES TO THERAPY. Klinik fanlar yilnomasi, 2(1). https://tadqiqot.uz/index.php/spjacd/article/view/12087 |
|---|---|
| GOST (OAK) | Barnoyev S.Sh LIVER CONDITION IN BURN DISEASE PATHOGENETIC MECHANISMS, CLINICAL MANIFESTATIONS AND APPROACHES TO THERAPY // Klinik fanlar yilnomasi. – 2025. – T. 2, № 1. |
| MLA | Barnoyev S.Sh. “LIVER CONDITION IN BURN DISEASE PATHOGENETIC MECHANISMS, CLINICAL MANIFESTATIONS AND APPROACHES TO THERAPY.” Klinik fanlar yilnomasi, 2(1), 2025. https://tadqiqot.uz/index.php/spjacd/article/view/12087 |
| Chicago | Barnoyev S.Sh. “LIVER CONDITION IN BURN DISEASE PATHOGENETIC MECHANISMS, CLINICAL MANIFESTATIONS AND APPROACHES TO THERAPY.” Klinik fanlar yilnomasi, 2(1) (2025). https://tadqiqot.uz/index.php/spjacd/article/view/12087 |
| Harvard | Barnoyev S.Sh (2025) ‘LIVER CONDITION IN BURN DISEASE PATHOGENETIC MECHANISMS, CLINICAL MANIFESTATIONS AND APPROACHES TO THERAPY’, Klinik fanlar yilnomasi, 2(1). https://tadqiqot.uz/index.php/spjacd/article/view/12087 |
| BibTeX | @article{barnoyevssh2025,
title = {LIVER CONDITION IN BURN DISEASE PATHOGENETIC MECHANISMS, CLINICAL MANIFESTATIONS AND APPROACHES TO THERAPY},
author = {Barnoyev S.Sh},
journal = {Klinik fanlar yilnomasi},
year = {2025},
volume = {2},
number = {1},
url = {https://tadqiqot.uz/index.php/spjacd/article/view/12087}
} |
Boshqa maqola uchun iqtibos tayyorlash
Metabolically associated fatty liver disease (MAFLD) is a widespread chronic condition characterized by a high degree of fat accumulation in the liver due to metabolic dysfunction. Over the past 10 years, the rate of…
Hepatorenal syndrome (HRS) represents a severe complication in patients with advanced liver cirrhosis, characterized by rapid deterioration of renal function in the absence of structural kidney disease. While the…
Mitral regurgitation (MR) is the second most common and frequent indication for cardiac surgery valvular heart disease. Severe MR is characterized by a significant decrease in exercise tolerance and high mortality. The…
Parkinson’s disease (PD) is a widespread neurodegenerative disorder characterized by progressive development and the presence of both motor and non-motor symptoms. Secondary parkinsonism is a complication of another…
The article presents a comparative analysis of microbial contamination and the dynamics of contamination in non-gunshot soft tissue wounds using a new method of primary wound management. The aim of this study was to…
Monitoring the depth of anesthesia is a key component of modern anesthesia aimed at optimizing the dosing of anesthetics and minimizing the risk of both under- and overanesthesia. This article discusses the role of…
A total of 150 military personnel (40 women and 110 men, aged 40 to 55 years) diagnosed with chronic cerebral ischemia were examined and treated at the Central Military Clinical Hospital of the Ministry of Defense of…
The article examines the state of the autonomic nervous system before and after the use of sulpiride in quadruple therapy in patients with Helicobacter pylori — the causative agent of gastric ulcer and duodenal ulcer…
To conduct experimental studies in the simulation of acute purulent liver abscess, a technique was used that involved the initiation of a 7 mm diameter gauze ball soaked in fecal microflora from the cecal region at a…
Spondyloarthritis (SpA) is an inflammatory rheumatological disease affecting the axial skeleton, peripheral joints and tendons, as well as extra-skeletal areas. In more recent nomenclature, SpA is divided into axial and…
Klinik fanlar yilnomasi — barcha maqolalar · 2025-yil arxivi
Настоящее исследование посвящено разработке алгоритма раннего выявления сенсоневральной тугоухости у детей с использованием методов полимеразной цепной реакции (ПЦР). Обследовано 235 детей с нарушениями слуха, из…
В статье представлены клинические аспекты и диагностические проблемы выявления сенсоневральной тугоухости у новорождённых с перинатальной патологией. Обследовано 115 новорождённых, из которых 35 перенесли асфиксию, а у…
Сенсоневральная тугоухость (СНТ) у детей остаётся одной из наиболее актуальных проблем современной оториноларингологии и медицинской генетики. Ранняя диагностика нарушений слуха играет ключевую роль в предупреждении…
Сенсоневральная тугоухость у новорождённых является одной из ведущих причин нарушения слухоречевого развития и ранней инвалидизации. Наиболее уязвимыми считаются дети, перенёсшие перинатальные осложнения, такие как…
Mazkur eksperimental tadqiqotda yuqori yog‘li ratsion va seftriaksonning lipid hamda uglevod almashinuviga alohida va birgalikdagi ta’siri 160 ta oq zotsiz erkak kalamushda o‘rganildi. Tajriba hayvonlari to‘rtta guruhga…
Мазкур тадқиқотда Тошкет вилоятидаги Ўрта Чирчиқ тумани 25-сонли, Бўка тумани 3-сонли ва 9-сонли давлат мактабгача таълим ташкилотларида 2025 йил ёз мавсумидаги таомномаларнинг озиқ-овқат маҳсулотлари билан…