Neuroinflammation plays a crucial role in the pathogenesis of autism spectrum disorders (ASD), representing a complex process that includes the activation of immune cells in the brain, an imbalance of pro-inflammatory and anti-inflammatory cytokines, as well as disruption of the blood- brain barrier function. Studies show that increased production of interleukins such as IL-6, IL-10, and TNF-α is associated with changes in synaptic plasticity, neuronal hyperexcitability, and impaired neurogenesis processes, which may contribute to the development of the autistic phenotype.
| Mualliflar | Фарангисбону Алишер кизи Дониёрова |
|---|---|
| Jurnal | Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research |
| Nashr sanasi | 2025-05-18 |
| Jild | 6 |
| Son | 3 |
| Til | Rus |
Аутизм, РАС, нейровоспалительные профессы, интерлейкины, Autism, ASD, neuroinflammatory processes, interleukins, Autizm, ASB, neyrovospalanuv jarayonlar, interleykinlar
Objective. Based on the literature analysis, to study the mechanisms of development, clinical course, structure of precancerous diseases of the uterus in women of fertile age, to analyze the psychopathological state…
The article presents the specificity of blood coagulation parameters such as hematocrit, thrombin time, fibrinogen, etalon test, thrombotest in hemorrhagic stroke and type 2 diabetes mellitus, and the dependence of…
Post-hemodialysis encephalopathy (PHE) refers to neurological changes that can occur in the brain of patients with chronic kidney disease after undergoing hemodialysis. These changes can lead to impairments in brain…
The article presents clinical cases with a diagnosis of congenital and acquired microcephaly encountered in our work. We believe that it is necessary to conduct a study on this nosology based on a deep analysis…
Perinatal damage to the central nervous system (PDCNS) is one of the leading causes of neurological pathologies in newborns and young children. The study of the etiopathogenesis of this pathology plays a major role in…
This article analyzes literature data on the characteristics of the development of neurofibromatosis in children. An analysis of the studied scientific and medical literature showed that many unresolved problems remain…
The pathogenesis of juvenile rheumatoid arthritis (JRA) is a complex process in which genetic, immune, and environmental factors interact. One aspect that has attracted research attention is the role of homocysteine, an…
A thorough analysis of the data of modern scientific literature shows that, from the point of view of the effectiveness of rehabilitation, the form of spastic diplegia of cerebral palsy is the most promising. Such…
In patients with initial manifestations of cerebral blood supply insufficiency endonasal electrophoresis with tanacan (EGb 761) has a positive effect not only on the clinical condition of patients, but also on…
This article is devoted to the study of the impact of a new coronavirus infection suffered by a woman during pregnancy on the course of pregnancy and the health of her newborn child. Cases of congenital malformations…