This study evaluates the clinical and immunological parameters of patients with multiple sclerosis and investigates the efficacy of immunomodulatory and neuro-metabolic therapy. A total of 64 patients were examined, including 34 in the clinical-radiological dissociative (CRD) group and 30 in the control group. Assessments based on EDSS and HADS scales showed that the combination therapy (placental hydrolysate and monosialoganglioside GM1) significantly reduced disability levels, improved psycho-emotional status, and helped normalize cognitive functions. Immunological indicators also showed a decrease in IL-6, IL-8, and TNF-α levels. These results confirm that the combined treatment methods are effective in treating multiple sclerosis.
| Mualliflar | Халимова Ханифа Мухсиновна, Якубова Мархамат Миракрамовна, Парпиева Юлдуз Равшановна, Рашидова Нилуфар Сафаевна |
|---|---|
| Jurnal | Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research |
| Nashriyot | Бухоро давлат тиббиёт институти |
| Nashr sanasi | 2025-02-16 |
| Jild | 6 |
| Son | 1 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-26 |
рассеянный склероз, иммуномодуляция, нейрометаболическая терапия, плацентарный гидролизат, моносиалоганглиозид, EDSS, HADS, когнитивные функции, multiple sclerosis, immunomodulation, neuro-metabolic therapy, placental hydrolysate, monosialoganglioside, EDSS, HADS, cognitive functions, тарқоқ склероз, иммуномодуляция, нейрометаболик терапия, плацентар гидролизат, моносиалоганглиозид, EDSS, HADS, когнитив функциялар
| APA | Халимова Ханифа Мухсиновна, Якубова Мархамат Миракрамовна, Парпиева Юлдуз Равшановна, & Рашидова Нилуфар Сафаевна (2025). CLINICAL-RADIOLOGICAL DISSOCIATION IN MULTIPLE SCLEROSIS AND OPTIMIZATION OF ITS THERAPEUTIC MANAGEMENT. Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(1). https://tadqiqot.uz/index.php/neurology/article/view/10989 |
|---|---|
| GOST (OAK) | Халимова Ханифа Мухсиновна va b. CLINICAL-RADIOLOGICAL DISSOCIATION IN MULTIPLE SCLEROSIS AND OPTIMIZATION OF ITS THERAPEUTIC MANAGEMENT // Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research. – 2025. – T. 6, № 1. |
| MLA | Халимова Ханифа Мухсиновна, Якубова Мархамат Миракрамовна, Парпиева Юлдуз Равшановна, and Рашидова Нилуфар Сафаевна. “CLINICAL-RADIOLOGICAL DISSOCIATION IN MULTIPLE SCLEROSIS AND OPTIMIZATION OF ITS THERAPEUTIC MANAGEMENT.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(1), 2025. https://tadqiqot.uz/index.php/neurology/article/view/10989 |
| Chicago | Халимова Ханифа Мухсиновна, Якубова Мархамат Миракрамовна, Парпиева Юлдуз Равшановна, and Рашидова Нилуфар Сафаевна. “CLINICAL-RADIOLOGICAL DISSOCIATION IN MULTIPLE SCLEROSIS AND OPTIMIZATION OF ITS THERAPEUTIC MANAGEMENT.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(1) (2025). https://tadqiqot.uz/index.php/neurology/article/view/10989 |
| Harvard | Халимова Ханифа Мухсиновна, Якубова Мархамат Миракрамовна, Парпиева Юлдуз Равшановна, and Рашидова Нилуфар Сафаевна (2025) ‘CLINICAL-RADIOLOGICAL DISSOCIATION IN MULTIPLE SCLEROSIS AND OPTIMIZATION OF ITS THERAPEUTIC MANAGEMENT’, Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(1). https://tadqiqot.uz/index.php/neurology/article/view/10989 |
| BibTeX | @article{article2025,
title = {CLINICAL-RADIOLOGICAL DISSOCIATION IN MULTIPLE SCLEROSIS AND OPTIMIZATION OF ITS THERAPEUTIC MANAGEMENT},
author = {Халимова Ханифа Мухсиновна and Якубова Мархамат Миракрамовна and Парпиева Юлдуз Равшановна and Рашидова Нилуфар Сафаевна},
journal = {Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research},
year = {2025},
volume = {6},
number = {1},
url = {https://tadqiqot.uz/index.php/neurology/article/view/10989}
} |
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