This study evaluates the clinical and immunological parameters of patients with multiple sclerosis and investigates the efficacy of immunomodulatory and neuro-metabolic therapy. A total of 64 patients were examined, including 34 in the clinical-radiological dissociative (CRD) group and 30 in the control group. Assessments based on EDSS and HADS scales showed that the combination therapy (placental hydrolysate and monosialoganglioside GM1) significantly reduced disability levels, improved psycho-emotional status, and helped normalize cognitive functions. Immunological indicators also showed a decrease in IL-6, IL-8, and TNF-α levels. These results confirm that the combined treatment methods are effective in treating multiple sclerosis.
Ходжиева Дилбар Тажиевна, Тешаева Малика Қахрамоновна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-02-16
This article is devoted to the identification of clinical and pathogenetic features of ischemic stroke and risk factors leading to it in women with metabolic syndrome. In our study, we identified body mass index, waist…
НИЯЗОВ Шухрат Тоштемирович, ДЖУРАБЕКОВА Азиза Тахировна, КАЮМОВА Мохинур Бахтиёр кизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-02-16
Monosymptomatic primary nocturnal enuresis (MPNE) is a widespread pathology among children and adolescents that significantly impacts their quality of life and can lead to serious psychosocial problems. According to the…
Хасанова Камола Мусаджановна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-02-16
In our study, 116 people were diagnosed with coronary heart disease, persistent angina, insomnia and drowsiness. All patients underwent neuropsychological tests, biochemical and instrumental studies, and…
Югай Игорь Александрович, Ахмедиев Махмуд Мансурович, Хазраткулов Рустам Бафоевич · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-02-16
Objective: To analyze the literature on diagnostic criteria for tethered cord syndrome and to determine indications for surgical treatment. Materials and Methods: An extensive search was performed to identify…
Эшчанова Гузал Бакпулатовна, Babadjanov Jasurbek Kamiljanovich, Матмуродов Рустамбек Жуманазарович, Жуманазарова Шахзода Рустамбековна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-02-16
The article provides a review of the Haki literature on neurological complications of chronic limfoleicosis. The clinical description of the disease is fully covered, the main issues of diagnosis and treatment are…
Мансурова Наргиза Асроровна, Жабборов Ботир Баходирович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-02-15
Chronic cerebral ischemia (CCI) represents a serious medical issue that affects a significant number of patients, particularly in older age groups. This condition is associated with insufficient blood supply to brain…
Тлеубергенова Азима Балтабаевна, Матмуродов Рустамбек Жуманазарович, Жуманазарова Шахзода Рустамбековна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-02-16
The article presents a review of the literature on the causes and risk factors for stroke in regions with unfavorable environmental conditions. The problems of the Aral Sea and the Aral Sea region are highlighted, and…
Мирджураев Элбек Миршавкатович, Мухамедалиева Нигора Мусурмановна, Искандарова Дилрабо Комилжоновна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-02-15
The article presents various neurological complications after coronavirus infection in employees of the Ministry of Internal Affairs, analyzes the prevalence rates and the importance of working conditions of employees…
Сойибов Иброхим Эшмухамадович, Ахмедиев Махмуд Мансурович, Тулаев Нодирбек Бекмуродович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-02-16
The article describes a clinical case of successful conservative treatment of a patient with multiple abscesses in the left hemisphere of the brain. The course, clinical manifestations of the disease, as well as the…
Адаббаев Зуфар Ибрагимович, Киличев Ибодулла Абдуллаевич, Худайберганов Нурмамат Юсупович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-02-15
Relevance and objectives. The aim of the study was to investigate the influence of high temperatures and geomagnetic storms on the development of cerebral strokes in men in the Aral Sea region using the example of the…