Genetic predictors of kidney damage in preeclampsia

Mirzayeva G.P.

Ёш олимлар тиббиёт журнали · 2026-yil

Annotatsiya

This literature review analyzes genetic factors contributing to the development of renal involvement in preeclampsia based on recent scientific studies. Preeclampsia is a multifactorial complication of pregnancy in which genetic predisposition plays a significant role in its pathogenesis. According to various studies, the genetic component may account for up to 40–50% of the etiology of preeclampsia. Renal dysfunction is manifested through gene polymorphisms associated with endothelial dysfunction, alterations in vascular tone, activation of the coagulation system, and inflammatory processes. Particular attention is paid to genes involved in endothelial function, angiogenesis, cytokine regulation, the coagulation system, and the renin–angiotensin system, which are considered the main genetic predictors of renal damage in preeclampsia. Advances in modern genetics and molecular biology enable early prediction of renal involvement in preeclampsia and the development of individualized management strategies.

Maqola ma’lumotlari
MualliflarMirzayeva G.P.
JurnalЁш олимлар тиббиёт журнали
NashriyotТошкент тиббиёт академияси
ISSN2181-3485
Nashr sanasi2026-03-09
Son17
Betlar333-337
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

preeclampsia, renal damage, genetic predictors, gene polymorphism, endothelial dysfunction, angiogenesis, coagulation system.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAMirzayeva G.P. (2026). GENETIC PREDICTORS OF KIDNEY DAMAGE IN PREECLAMPSIA. Ёш олимлар тиббиёт журнали, (17), 333-337. https://journals.tnmu.uz/index.php/yotj/article/view/4157
GOST (OAK)Mirzayeva G.P. GENETIC PREDICTORS OF KIDNEY DAMAGE IN PREECLAMPSIA // Ёш олимлар тиббиёт журнали. – 2026. – № 17. – P. 333-337.
MLAMirzayeva G.P. “GENETIC PREDICTORS OF KIDNEY DAMAGE IN PREECLAMPSIA.” Ёш олимлар тиббиёт журнали, (17), 333-337, 2026. https://journals.tnmu.uz/index.php/yotj/article/view/4157
ChicagoMirzayeva G.P. “GENETIC PREDICTORS OF KIDNEY DAMAGE IN PREECLAMPSIA.” Ёш олимлар тиббиёт журнали, (17), 333-337 (2026). https://journals.tnmu.uz/index.php/yotj/article/view/4157
HarvardMirzayeva G.P (2026) ‘GENETIC PREDICTORS OF KIDNEY DAMAGE IN PREECLAMPSIA’, Ёш олимлар тиббиёт журнали, (17), 333-337. https://journals.tnmu.uz/index.php/yotj/article/view/4157
BibTeX
@article{mirzayevagp2026,
  title = {GENETIC PREDICTORS OF KIDNEY DAMAGE IN PREECLAMPSIA},
  author = {Mirzayeva G.P.},
  journal = {Ёш олимлар тиббиёт журнали},
  year = {2026},
  number = {17},
  pages = {333-337},
  url = {https://journals.tnmu.uz/index.php/yotj/article/view/4157}
}

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