This study evaluates the anti-inflammatory activity of Astragalus krauseanus extract under experimental conditions. White rats were treated orally with the extract at doses of 50, 100, and 200 mg/kg for 7 days. Acute inflammation was induced using acetic acid–induced peritonitis and formalin-induced edema models. Anti-inflammatory activity was assessed based on exudate volume and paw edema. The results showed that the extract reduced the exudative phase of inflammation by 31–43% at all tested doses. In the formalin-induced edema model, anti-inflammatory effects ranged from 43.0% to 62.2%. At some doses, the efficacy of the extract was comparable to or higher than that of ketoprofen. These findings indicate that Astragalus krauseanus extract exhibits significant anti-inflammatory activity and may be considered a promising biologically active substance for further pharmacological studies.
| Mualliflar | Umidakhon Vakhobkhon kizi, Mukimjonova, Ibrohimjon Rakhmonovich, Askarov, Obidjon Shaxabiddinovich, Abdulloyev |
|---|---|
| Jurnal | Қўқон ДПИ. Илмий хабарлар |
| Nashr sanasi | 2026-02-28 |
| Jild | 8 |
| Son | 2 |
| Betlar | 618-622 |
| Til | Ingliz |
| DOI | 10.70728/a.series.v08.i02.0084 |
DOI: 10.70728/a.series.v08.i02.0084 · Maqolaning asl sahifasi
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