Biological activity and classification of stereoisomers of 4–METHYL-4-ETHYL-5-METHYLENTHIAZOLIDIN-2-THIONES

Abdullayev, Tohir X.

Товарлар кимёси ва халқ табобати · 2026-yil

Annotatsiya

This article investigates the biological activity of optically active and racemic forms of 4-methyl-4-ethyl-5-methylenethiazolidine-2-thiones. During the study, the bacteriostatic and bactericidal effects of these compounds against various microorganisms, including Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Klebsiella, Proteus, and Shigella dysenteriae, were determined. The results showed that the (S)-(-) stereoisomer exhibits the highest antimicrobial activity, demonstrating effectiveness even at low concentrations. In addition, a comparative analysis of the biological activity of optical antipodes and their racemic mixture was carried out. Based on the obtained results, the classification of these compounds according to the Commodity Nomenclature of Foreign Economic Activity (TN VED) was established, and the code 2934 20 800 1 was proposed. The findings expand the prospects for the application of biologically active heterocyclic compounds in pharmaceutical and applied chemistry fields.

Maqola ma’lumotlari
MualliflarAbdullayev, Tohir X.
JurnalТоварлар кимёси ва халқ табобати
NashriyotТабобат академияси
ISSN2181-2977
Nashr sanasi2026-06-12
Jild5
Son2
Betlar33-44
TilIngliz
Ilmiy sohaKimyo
DOI10.55475/jcgtm/vol5.iss2.2026.639
Indeksga qo‘shilgan2026-08-26

DOI: 10.55475/jcgtm/vol5.iss2.2026.639 · Maqolaning asl sahifasi

Kalit so‘zlar

thiazolidine-2-thiones, stereoisomers, optically active compounds, racemate, antimicrobial activity, bacteriostatic effect, тиазолидин-2-тионы, стереоизомеры, оптически активные соединения, рацемат, антимикробная активность, бактериостатическое действие, tiazolidin-2-tionlar, stereoizomerlar, optik faol birikmalar, rasemat, antimikrob faollik, bakteriostatik ta’sir

Ilmiy soha

Kimyo

Iqtibos keltirish

APAAbdullayev, Tohir X. (2026). BIOLOGICAL ACTIVITY AND CLASSIFICATION OF STEREOISOMERS OF 4–METHYL-4-ETHYL-5-METHYLENTHIAZOLIDIN-2-THIONES. Товарлар кимёси ва халқ табобати, 5(2), 33-44. https://doi.org/10.55475/jcgtm/vol5.iss2.2026.639
GOST (OAK)Abdullayev, Tohir X. BIOLOGICAL ACTIVITY AND CLASSIFICATION OF STEREOISOMERS OF 4–METHYL-4-ETHYL-5-METHYLENTHIAZOLIDIN-2-THIONES // Товарлар кимёси ва халқ табобати. – 2026. – T. 5, № 2. – P. 33-44. – DOI: 10.55475/jcgtm/vol5.iss2.2026.639.
MLAAbdullayev, Tohir X. “BIOLOGICAL ACTIVITY AND CLASSIFICATION OF STEREOISOMERS OF 4–METHYL-4-ETHYL-5-METHYLENTHIAZOLIDIN-2-THIONES.” Товарлар кимёси ва халқ табобати, 5(2), 33-44, 2026. https://doi.org/10.55475/jcgtm/vol5.iss2.2026.639
ChicagoAbdullayev, Tohir X. “BIOLOGICAL ACTIVITY AND CLASSIFICATION OF STEREOISOMERS OF 4–METHYL-4-ETHYL-5-METHYLENTHIAZOLIDIN-2-THIONES.” Товарлар кимёси ва халқ табобати, 5(2), 33-44 (2026). https://doi.org/10.55475/jcgtm/vol5.iss2.2026.639
HarvardAbdullayev, Tohir X (2026) ‘BIOLOGICAL ACTIVITY AND CLASSIFICATION OF STEREOISOMERS OF 4–METHYL-4-ETHYL-5-METHYLENTHIAZOLIDIN-2-THIONES’, Товарлар кимёси ва халқ табобати, 5(2), 33-44. https://doi.org/10.55475/jcgtm/vol5.iss2.2026.639
BibTeX
@article{abdullayevtohirx2026,
  title = {BIOLOGICAL ACTIVITY AND CLASSIFICATION OF STEREOISOMERS OF 4–METHYL-4-ETHYL-5-METHYLENTHIAZOLIDIN-2-THIONES},
  author = {Abdullayev, Tohir X.},
  journal = {Товарлар кимёси ва халқ табобати},
  year = {2026},
  volume = {5},
  number = {2},
  pages = {33-44},
  doi = {10.55475/jcgtm/vol5.iss2.2026.639},
  url = {https://doi.org/10.55475/jcgtm/vol5.iss2.2026.639}
}

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