Tumor-associated macrophages (tams) and their biological functions

Mamajonov, Zafar A., Ulug’bekova, Gulrukhan J., Mamatova, Iroda Yu.

Товарлар кимёси ва халқ табобати · 2025-yil

Annotatsiya

Tumor-associated macrophages (TAMs) are one of the most abundant immune cell populations in the tumor microenvironment (TME). By interacting with tumor and stromal cells, TAMs promote angiogenesis, suppress adaptive immunity, and facilitate metastasis. Most TAMs resemble the M2-like phenotype, secreting immunosuppressive and pro-tumorigenic factors such as IL-10, TGF-β, and VEGF. Their functional reprogramming has been recognized as a promising target in cancer immunotherapy.

Maqola ma’lumotlari
MualliflarMamajonov, Zafar A., Ulug’bekova, Gulrukhan J., Mamatova, Iroda Yu.
JurnalТоварлар кимёси ва халқ табобати
NashriyotТабобат академияси
ISSN2181-2977
Nashr sanasi2025-12-28
Jild4
Son5
Betlar132-143
TilIngliz
Ilmiy sohaTibbiyot
DOI10.55475/jcgtm/vol4.iss5.2025.538
Indeksga qo‘shilgan2026-08-26

DOI: 10.55475/jcgtm/vol4.iss5.2025.538 · Maqolaning asl sahifasi

Kalit so‘zlar

Tumor-associated macrophages (TAMs), M1/M2 polarization, angiogenesis, immunosuppression, metastasis, Oпухоле-ассоциированные макрофаги (TAMs), поляризация M1/M2, ангиогенез, иммуносупрессия, метастазы, Saraton bilan bog‘liq makrofaglar (TAMs), M1/M2 polarizatsiya, angiogenez, immun bostirish, metastaz

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAMamajonov, Zafar A., Ulug’bekova, Gulrukhan J., & Mamatova, Iroda Yu. (2025). TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS. Товарлар кимёси ва халқ табобати, 4(5), 132-143. https://doi.org/10.55475/jcgtm/vol4.iss5.2025.538
GOST (OAK)Mamajonov, Zafar A., Ulug’bekova, Gulrukhan J., Mamatova, Iroda Yu. TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS // Товарлар кимёси ва халқ табобати. – 2025. – T. 4, № 5. – P. 132-143. – DOI: 10.55475/jcgtm/vol4.iss5.2025.538.
MLAMamajonov, Zafar A., Ulug’bekova, Gulrukhan J., and Mamatova, Iroda Yu. “TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS.” Товарлар кимёси ва халқ табобати, 4(5), 132-143, 2025. https://doi.org/10.55475/jcgtm/vol4.iss5.2025.538
ChicagoMamajonov, Zafar A., Ulug’bekova, Gulrukhan J., and Mamatova, Iroda Yu. “TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS.” Товарлар кимёси ва халқ табобати, 4(5), 132-143 (2025). https://doi.org/10.55475/jcgtm/vol4.iss5.2025.538
HarvardMamajonov, Zafar A., Ulug’bekova, Gulrukhan J., and Mamatova, Iroda Yu (2025) ‘TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS’, Товарлар кимёси ва халқ табобати, 4(5), 132-143. https://doi.org/10.55475/jcgtm/vol4.iss5.2025.538
BibTeX
@article{mamajonovzafara2025,
  title = {TUMOR-ASSOCIATED MACROPHAGES (TAMS) AND THEIR BIOLOGICAL FUNCTIONS},
  author = {Mamajonov, Zafar A. and Ulug’bekova, Gulrukhan J. and Mamatova, Iroda Yu.},
  journal = {Товарлар кимёси ва халқ табобати},
  year = {2025},
  volume = {4},
  number = {5},
  pages = {132-143},
  doi = {10.55475/jcgtm/vol4.iss5.2025.538},
  url = {https://doi.org/10.55475/jcgtm/vol4.iss5.2025.538}
}

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