Aim. Beating-heart continuous coronary perfusion (BHCCP) is an alternative to cardioplegic arrest in valve surgery, potentially reducing ischemic reperfusion injury, especially in high-risk patients with low left ventricular ejection fraction (LVEF). Materials and methods. A systematic review of prospective and observational studies was conducted, focusing on BHCCP versus cardioplegia in valve surgery, with emphasis on patients with LVEF <35%. Results. Studies (e.g., Matsumoto et al., 2002) showed no significant difference in mortality or major complications, but BHCCP reduced myocardial damage markers (e.g., Troponin I, CK-MB) by 20–40% compared to cardioplegia. Clinical outcomes remained comparable across groups. Conclusion. BHCCP is a safe alternative to cardioplegia, with potential benefits in myocardial protection, though high-quality randomized trials are needed to confirm clinical superiority.
| Mualliflar | Хайруллаев, У, Муллабаева, Г, Шарипов, И, Xayrullaev , Umid, Mullabaeva , Guzal, Sharipov, Islamjan, Khayrullaev , Umid, Mullabaeva, Guzal, Sharipov, Islamjan |
|---|---|
| Jurnal | O‘zbekiston кardiologiyasi |
| Nashr sanasi | 2025-06-30 |
| Jild | 2 |
| Son | 2 |
| Betlar | 145-151 |
| Til | Rus |
| DOI | 10.70626/cardiouz-2025-2-00046 |
DOI: 10.70626/cardiouz-2025-2-00046 · Maqolaning asl sahifasi
Continuous perfusion, Beating heart, Heart valves, Myocardial protection, Cardioplegia, Непрерывная перфузия, Работающее сердце, Клапаны сердца, Защита миокарда, Кардиоплегия, Uzluksiz perfuziya, Ishlayotgan yurak, Yurak klapanlari, Miokardni himoya qilish, Kardioplegiya
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