Morphological changes in the thymus during acute exposure to a defoliant

KIYOMOV Ixtiyor Ergashеvich, ISLAMOV Shavkat Erjigitovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2026-yil

Annotatsiya

This article examines morphological reactive-dystrophic changes developing in the thymic stroma under the influence of Ento Defol. Specifically, a single high dose of the defoliant (1/10 LD50) resulted in a reactive thickening of collagen fibers in the interlobular barriers of the thymus and perivascular zones. These changes were assessed as a compensatory response developing against the background of interstitial edema and microcirculatory disturbances. A sharp increase in the number of mast cells in the perivascular and subcapsular zones, along with clear signs of degranulation, was also detected. Increased metachromasia indicated the activation of reactive inflammatory processes associated with the release of biologically active substances.

Maqola ma’lumotlari
MualliflarKIYOMOV Ixtiyor Ergashеvich, ISLAMOV Shavkat Erjigitovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2026-04-21
Jild11
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

вилочковая железа, крыса, дефолиант, Энто Дефол, морфологические изменения, thymus gland, rat, defoliant, Ento Defol, morphological changes, timus, kalamush, dеfoliant, Ento Dеfol, morfologik oʻzgarishlar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAKIYOMOV Ixtiyor Ergashеvich, & ISLAMOV Shavkat Erjigitovich (2026). MORPHOLOGICAL CHANGES IN THE THYMUS DURING ACUTE EXPOSURE TO A DEFOLIANT. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(1). https://tadqiqot.uz/index.php/biomedicine/article/view/13469
GOST (OAK)KIYOMOV Ixtiyor Ergashеvich, ISLAMOV Shavkat Erjigitovich MORPHOLOGICAL CHANGES IN THE THYMUS DURING ACUTE EXPOSURE TO A DEFOLIANT // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2026. – T. 11, № 1.
MLAKIYOMOV Ixtiyor Ergashеvich, and ISLAMOV Shavkat Erjigitovich. “MORPHOLOGICAL CHANGES IN THE THYMUS DURING ACUTE EXPOSURE TO A DEFOLIANT.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(1), 2026. https://tadqiqot.uz/index.php/biomedicine/article/view/13469
ChicagoKIYOMOV Ixtiyor Ergashеvich, and ISLAMOV Shavkat Erjigitovich. “MORPHOLOGICAL CHANGES IN THE THYMUS DURING ACUTE EXPOSURE TO A DEFOLIANT.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(1) (2026). https://tadqiqot.uz/index.php/biomedicine/article/view/13469
HarvardKIYOMOV Ixtiyor Ergashеvich, and ISLAMOV Shavkat Erjigitovich (2026) ‘MORPHOLOGICAL CHANGES IN THE THYMUS DURING ACUTE EXPOSURE TO A DEFOLIANT’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(1). https://tadqiqot.uz/index.php/biomedicine/article/view/13469
BibTeX
@article{kiyomovixtiyorergashvich2026,
  title = {MORPHOLOGICAL CHANGES IN THE THYMUS DURING ACUTE EXPOSURE TO A DEFOLIANT},
  author = {KIYOMOV Ixtiyor Ergashеvich and ISLAMOV Shavkat Erjigitovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2026},
  volume = {11},
  number = {1},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/13469}
}

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