Ways to reduce the negative consequences for the mother and newborn in women with hepatitis b during pregnancy

ZUFAROVA Shaxnoza Alimdjanovna, AZIMOVA Komila Islomovna

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2026-yil

Annotatsiya

Chronic hepatitis B (HBV) remains one of the leading infectious causes of adverse pregnancy outcomes and perinatal pathology. Viral replication, accompanied by cytolytic syndrome and impaired metabolic functions of the liver, leads to an increased incidence of gestosis, anemia, placental insufficiency, premature birth and the risk of vertical transmission of infection. The proposed comprehensive management of pregnant women with chronic hepatitis B ensured a reduction in viral load by more than 2.6 times (p<0.01), normalization of ALT, AST and bilirubin, and a reduction in the degree of fibrosis according to elastography (FibroScan CAP). The incidence of obstetric complications decreased by 1.5–2 times, and preterm births decreased from 16.1% to 8.1% (p<0.05). Cardiotocography results in the third trimester in patients in the study group showed a significant increase in heart rate variability and acceleration rate (p<0.01), a decrease in late decelerations, and normalization of the fetal condition index (FCI=1.10±0.25). The body weight and viability of newborns were higher, and the frequency of vertical transmission of HBV decreased to 1.2% versus 5.7% (p<0.05). Comprehensive management of pregnant women with hepatitis B helps reduce viral activity, stabilize liver function, improve fetoplacental circulation, and prevent neonatal HBV infection.

Maqola ma’lumotlari
MualliflarZUFAROVA Shaxnoza Alimdjanovna, AZIMOVA Komila Islomovna
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2026-01-08
Jild10
Son6
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

беременность, хронический гепатит B, перинатальные исходы, иммунопрофилактика, pregnancy, chronic hepatitis B, perinatal outcomes, immunoprophylaxis, homiladorlik, surunkali gepatit B, perinatal natijalar, immunoprofilaktika

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAZUFAROVA Shaxnoza Alimdjanovna, & AZIMOVA Komila Islomovna (2026). WAYS TO REDUCE THE NEGATIVE CONSEQUENCES FOR THE MOTHER AND NEWBORN IN WOMEN WITH HEPATITIS B DURING PREGNANCY. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(6). https://tadqiqot.uz/index.php/biomedicine/article/view/13117
GOST (OAK)ZUFAROVA Shaxnoza Alimdjanovna, AZIMOVA Komila Islomovna WAYS TO REDUCE THE NEGATIVE CONSEQUENCES FOR THE MOTHER AND NEWBORN IN WOMEN WITH HEPATITIS B DURING PREGNANCY // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2026. – T. 10, № 6.
MLAZUFAROVA Shaxnoza Alimdjanovna, and AZIMOVA Komila Islomovna. “WAYS TO REDUCE THE NEGATIVE CONSEQUENCES FOR THE MOTHER AND NEWBORN IN WOMEN WITH HEPATITIS B DURING PREGNANCY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(6), 2026. https://tadqiqot.uz/index.php/biomedicine/article/view/13117
ChicagoZUFAROVA Shaxnoza Alimdjanovna, and AZIMOVA Komila Islomovna. “WAYS TO REDUCE THE NEGATIVE CONSEQUENCES FOR THE MOTHER AND NEWBORN IN WOMEN WITH HEPATITIS B DURING PREGNANCY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(6) (2026). https://tadqiqot.uz/index.php/biomedicine/article/view/13117
HarvardZUFAROVA Shaxnoza Alimdjanovna, and AZIMOVA Komila Islomovna (2026) ‘WAYS TO REDUCE THE NEGATIVE CONSEQUENCES FOR THE MOTHER AND NEWBORN IN WOMEN WITH HEPATITIS B DURING PREGNANCY’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(6). https://tadqiqot.uz/index.php/biomedicine/article/view/13117
BibTeX
@article{zufarovashaxnozaalimdjanovna2026,
  title = {WAYS TO REDUCE THE NEGATIVE CONSEQUENCES FOR THE MOTHER AND NEWBORN IN WOMEN WITH HEPATITIS B DURING PREGNANCY},
  author = {ZUFAROVA Shaxnoza Alimdjanovna and AZIMOVA Komila Islomovna},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2026},
  volume = {10},
  number = {6},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/13117}
}

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