Pathogenetic mechanisms of "Epithelial-mesenchymal transitions" in the development of adhesive disease during surgical interventions in gynecology

ZUFAROVA Shakhnoza Alimdzhanovna, ESHDAVLATOV Ilkhom Eshniyazovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

The article presents data on the participation of "epithelial-mesenchymal transitions" in the pathogenetic mechanism of adhesion process development in women who have undergone gynecological surgeries. The pathogenetic mechanism of participation of matrix metalloproteinases-2 and 9 and tumor necrosis factor-a in the development of adhesions in women who have undergone gynecological surgeries has been proven. Their high levels indicate a destructive effect on the extracellular matrix, creating conditions for the development of adhesions due to the growth of fibrous tissue. The range of MMP-2 levels >400 pg/ml, MMP-9 >350 pg/ml and TNF-α >45 pg/ml in determining the risk of adhesions after gynecological surgeries has been established.

Maqola ma’lumotlari
MualliflarZUFAROVA Shakhnoza Alimdzhanovna, ESHDAVLATOV Ilkhom Eshniyazovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-02-11
Jild9
Son6
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

женщины, спаечная болезнь, патогенез, матриксные металлопротеиназы, фактор некроза опухоли, women, adhesive disease, pathogenesis, matrix metalloproteinases, tumor necrosis factor, ayollar, bitishma kasallik, patogenez, matritsali metalloproteinazalar, o'simta nekrozi omili

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAZUFAROVA Shakhnoza Alimdzhanovna, & ESHDAVLATOV Ilkhom Eshniyazovich (2025). PATHOGENETIC MECHANISMS OF "EPITHELIAL-MESENCHYMAL TRANSITIONS" IN THE DEVELOPMENT OF ADHESIVE DISEASE DURING SURGICAL INTERVENTIONS IN GYNECOLOGY. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(6). https://tadqiqot.uz/index.php/biomedicine/article/view/10914
GOST (OAK)ZUFAROVA Shakhnoza Alimdzhanovna, ESHDAVLATOV Ilkhom Eshniyazovich PATHOGENETIC MECHANISMS OF "EPITHELIAL-MESENCHYMAL TRANSITIONS" IN THE DEVELOPMENT OF ADHESIVE DISEASE DURING SURGICAL INTERVENTIONS IN GYNECOLOGY // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 9, № 6.
MLAZUFAROVA Shakhnoza Alimdzhanovna, and ESHDAVLATOV Ilkhom Eshniyazovich. “PATHOGENETIC MECHANISMS OF "EPITHELIAL-MESENCHYMAL TRANSITIONS" IN THE DEVELOPMENT OF ADHESIVE DISEASE DURING SURGICAL INTERVENTIONS IN GYNECOLOGY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(6), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/10914
ChicagoZUFAROVA Shakhnoza Alimdzhanovna, and ESHDAVLATOV Ilkhom Eshniyazovich. “PATHOGENETIC MECHANISMS OF "EPITHELIAL-MESENCHYMAL TRANSITIONS" IN THE DEVELOPMENT OF ADHESIVE DISEASE DURING SURGICAL INTERVENTIONS IN GYNECOLOGY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(6) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/10914
HarvardZUFAROVA Shakhnoza Alimdzhanovna, and ESHDAVLATOV Ilkhom Eshniyazovich (2025) ‘PATHOGENETIC MECHANISMS OF "EPITHELIAL-MESENCHYMAL TRANSITIONS" IN THE DEVELOPMENT OF ADHESIVE DISEASE DURING SURGICAL INTERVENTIONS IN GYNECOLOGY’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(6). https://tadqiqot.uz/index.php/biomedicine/article/view/10914
BibTeX
@article{zufarovashakhnozaalimdzhanovna2025,
  title = {PATHOGENETIC MECHANISMS OF "EPITHELIAL-MESENCHYMAL TRANSITIONS" IN THE DEVELOPMENT OF ADHESIVE DISEASE DURING SURGICAL INTERVENTIONS IN GYNECOLOGY},
  author = {ZUFAROVA Shakhnoza Alimdzhanovna and ESHDAVLATOV Ilkhom Eshniyazovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {9},
  number = {6},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/10914}
}

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