MECHANISMS OF COMORBIDITY OF PERIODONTITIS AND INFLAMMATORY BOWEL PATHOLOGY (LITERATUREREVIEW)

BEKJANOVA Olga Esenovna, OLIMDJONOV Kamronbek Jasur o`g`li

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2024-yil

Annotatsiya

It has been proven that patients with IBP have an increased risk of developing periodontitis with a combined odds ratio of 3-5. In turn, patients with periodontitis have a higher risk of developing ulcerative colitis than patients without periodontitis. Thus, cohort studies prove the mutually reinforcing effect of periodontitis and IBP. Microorganisms play an important role in the pathogenesis of both pathologies (periodontitis and HCV). Microbial invasion plays an important role in the pathogenesis of both pathologies. The development of periodontitis is associated with the proliferation of periodontal pathogenic bacteria leading to the formation of periodontal pockets, the development of periodontal pathogenic bacteria is associated with the release of toxins and enzymes that contribute to their invasion into the mucous membrane of the gums in the depth of periodontal pockets.  The proliferation of periodontal pathogens significantly inhibits the host's immune defense, leading to the progression of inflammation. In the pathogenesis of IBP, in turn, it is important to disrupt the interaction between intestinal microorganisms and the immune system of the mucous membrane of the intestinal wall, which arise under the influence of adverse factors. It has been established that some types of microorganisms of the oral cavity can have a negative effect on the intestines.

Maqola ma’lumotlari
MualliflarBEKJANOVA Olga Esenovna, OLIMDJONOV Kamronbek Jasur o`g`li
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
Nashr sanasi2024-09-03
Jild9
Son3
TilRus

Kalit so‘zlar

заболевания тканей пародонта, воспалительные заболевания кишечника, микробная инвазия, специфические пародонтопатогены., periodontal tissue diseases, inflammatory bowel diseases, microbial invasion, specific periodontal pathogens, periodontal to'qima kasalliklari, ichakning yallig'lanish kasalliklari, mikrobial invaziya, o'ziga xos periodontopatogenlar

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