Anesthesiological determinants of perioperative outcomes in children with intestinal obstruction

Toshboev, Sherzod, Ne’matova, Ziyodaxon, Тошбоев, Шерзод, Неъматова, Зиёдахон, Toshboev, Sherzod, Ne’matova, Ziyodaxon

Халқаро илмий педиатрия журнали · 2026-yil

Annotatsiya

Intestinal obstruction in infants and young children is associated with high perioperative morbidity and mortality. Besides surgical factors, anesthesiological management and perioperative intensive care may significantly influence outcomes. Objective.This study aimed to identify perioperative predictors of adverse outcomes in children with intestinal obstruction and to evaluate anesthesiological management strategies. Methods. A retrospective observational study was conducted at the Andijan Regional Multidisciplinary Medical Center. Medical records of 99 children aged 0-3 years who underwent emergency surgery for intestinal obstruction were analyzed. Demographic, clinical, anesthetic, and perioperative variables were evaluated. Binary logistic regression and receiver operating characteristic (ROC) analysis were applied to identify independent predictors of adverse outcomes. Results. Adverse outcomes (severe complications and/or death) occurred in 34.3% of patients. Operation duration was identified as an independent predictor of adverse outcome (OR 1.064 per minute; 95% CI 1.023-1.107; p=0.002). Delayed hospital admission (>24 h) showed a borderline association with adverse outcome (p=0.057). The regression model demonstrated acceptable discrimination (AUC=0.722). Late hospital admission (>24 hours) was marginally associated with adverse outcomes (p=0.057). The regression model had satisfactory discriminant ability, with an area under the ROC curve (AUC) of 0.722. According to the results of the analysis, the duration of surgery was identified as an independent and reliable predictor of adverse clinical outcomes (OR=1.078; 95% CI: 1.028-1.131; p=0.002). This indicates that each additional minute of surgery increases the probability of developing an adverse clinical outcome by an average of 7-8%. This suggests that metabolic disorders associated with prolonged surgical time and increased surgical stress negatively affect clinical outcomes. Also, late hospital presentation (>24 hours) was noted as a significant factor significantly increasing the risk of adverse clinical outcomes (OR=9.20; 95% CI: 1.62-52.38; p=0.012). This result can be explained by the late diagnosis of the disease, increased risk of intestinal ischemia and infectious-septic complications. The type of anesthesia, in particular multimodal anesthesia, did not reach independent statistical significance within the multivariate model (p=0.301). Conclusion. Perioperative factors, particularly operation duration, play a critical role in determining outcomes in pediatric intestinal obstruction. Early hospital admission and optimization of anesthesiological management may contribute to improved clinical results.

Maqola ma’lumotlari
MualliflarToshboev, Sherzod, Ne’matova, Ziyodaxon, Тошбоев, Шерзод, Неъматова, Зиёдахон, Toshboev, Sherzod, Ne’matova, Ziyodaxon
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2026-01-19
Jild5
Son1
Betlar1178-1185
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2026-5-1-1178-1185
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2026-5-1-1178-1185 · Maqolaning asl sahifasi

Kalit so‘zlar

кишечная непроходимость, общая анестезия, эпидуральная анестезия, периоперационный период, факторы риска, младенцы, intestinal obstruction, general anesthesia, epidural anesthesia, perioperative period, risk factors, children, ichak tutilishi, umumiy anesteziya, epidural anesteziya, perioperatsion davr, xavf omillari, go‘daklar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAToshboev, Sherzod, Ne’matova, Ziyodaxon, Тошбоев, Шерзод, Неъматова, Зиёдахон, Toshboev, Sherzod, & Ne’matova, Ziyodaxon (2026). ANESTHESIOLOGICAL DETERMINANTS OF PERIOPERATIVE OUTCOMES IN CHILDREN WITH INTESTINAL OBSTRUCTION. Халқаро илмий педиатрия журнали, 5(1), 1178-1185. https://doi.org/10.56121/2181-2926-2026-5-1-1178-1185
GOST (OAK)Toshboev, Sherzod va b. ANESTHESIOLOGICAL DETERMINANTS OF PERIOPERATIVE OUTCOMES IN CHILDREN WITH INTESTINAL OBSTRUCTION // Халқаро илмий педиатрия журнали. – 2026. – T. 5, № 1. – P. 1178-1185. – DOI: 10.56121/2181-2926-2026-5-1-1178-1185.
MLAToshboev, Sherzod, Ne’matova, Ziyodaxon, Тошбоев, Шерзод, Неъматова, Зиёдахон, Toshboev, Sherzod, and Ne’matova, Ziyodaxon. “ANESTHESIOLOGICAL DETERMINANTS OF PERIOPERATIVE OUTCOMES IN CHILDREN WITH INTESTINAL OBSTRUCTION.” Халқаро илмий педиатрия журнали, 5(1), 1178-1185, 2026. https://doi.org/10.56121/2181-2926-2026-5-1-1178-1185
ChicagoToshboev, Sherzod, Ne’matova, Ziyodaxon, Тошбоев, Шерзод, Неъматова, Зиёдахон, Toshboev, Sherzod, and Ne’matova, Ziyodaxon. “ANESTHESIOLOGICAL DETERMINANTS OF PERIOPERATIVE OUTCOMES IN CHILDREN WITH INTESTINAL OBSTRUCTION.” Халқаро илмий педиатрия журнали, 5(1), 1178-1185 (2026). https://doi.org/10.56121/2181-2926-2026-5-1-1178-1185
HarvardToshboev, Sherzod, Ne’matova, Ziyodaxon, Тошбоев, Шерзод, Неъматова, Зиёдахон, Toshboev, Sherzod, and Ne’matova, Ziyodaxon (2026) ‘ANESTHESIOLOGICAL DETERMINANTS OF PERIOPERATIVE OUTCOMES IN CHILDREN WITH INTESTINAL OBSTRUCTION’, Халқаро илмий педиатрия журнали, 5(1), 1178-1185. https://doi.org/10.56121/2181-2926-2026-5-1-1178-1185
BibTeX
@article{toshboevsherzod2026,
  title = {ANESTHESIOLOGICAL DETERMINANTS OF PERIOPERATIVE OUTCOMES IN CHILDREN WITH INTESTINAL OBSTRUCTION},
  author = {Toshboev, Sherzod and Ne’matova, Ziyodaxon and Тошбоев, Шерзод and Неъматова, Зиёдахон and Toshboev, Sherzod and Ne’matova, Ziyodaxon},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2026},
  volume = {5},
  number = {1},
  pages = {1178-1185},
  doi = {10.56121/2181-2926-2026-5-1-1178-1185},
  url = {https://doi.org/10.56121/2181-2926-2026-5-1-1178-1185}
}

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