Immunohematological markers of inflammation in full-term newborns with congenital pneumonia

Turabidinova, Gullola, Turdieva, Shohida, Турабидинова, Гуллола, Турдиева, Шохида, Turabidinova, Gullola, Turdieva, Shohida

Халқаро илмий педиатрия журнали · 2026-yil

Annotatsiya

Relevance. Congenital pneumonia (СP) remains one of the most severe forms of perinatal infection, exerting a significant impact on neonatal morbidity and mortality. According to the World Health Organization (WHO), over 7 million children in early infancy suffer annually from the consequences of intrauterine infection, with more than 600,000 cases resulting in death during the neonatal and infant periods. The purpose . To assess the diagnostic value of leukocyte profile parameters in umbilical cord blood of newborns with intrauterine pneumonia. Materials and Methods. A prospective study was conducted involving 81 full-term newborns (gestational age 37–42 weeks), including 61 infants diagnosed with СP (main group) and 20 healthy newborns (control group). Umbilical cord blood samples were collected within the first hours of life to determine absolute leukocyte and lymphocyte counts. Statistical analysis included calculation of mean values, standard deviations, correlation coefficients (r), and significance levels (p). Results. Significant alterations in leukocyte profiles were observed in newborns with СP. The mean leukocyte count was 14.77 ± 0.512 × 10⁹/L, markedly higher than in the control group (9.87 ± 1.317 × 10⁹/L). A similar trend was noted for lymphocytes: 6.02 ± 0.719 × 10⁹/L versus 1.56 ± 0.361 × 10⁹/L. A moderate positive correlation was found between leukocyte and lymphocyte counts (r = 0.59; p < 0.05), indicating synchronized activation of the innate immune response. Peak levels were recorded on the third day of life. Conclusion. The leukocyte profile of umbilical cord blood serves as a valuable marker of inflammatory activity in СP and can be utilized for early immunological monitoring in newborns.

Maqola ma’lumotlari
MualliflarTurabidinova, Gullola, Turdieva, Shohida, Турабидинова, Гуллола, Турдиева, Шохида, Turabidinova, Gullola, Turdieva, Shohida
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2026-01-31
Jild5
Son1
Betlar1205-1212
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2026-5-1-1205-1212
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2026-5-1-1205-1212 · Maqolaning asl sahifasi

Kalit so‘zlar

новорождённые, пневмония, лейкоциты, лимфоциты, иммунная система, newborns, pneumonia, leukocytes, lymphocytes, immune system, yangi tug‘ilgan chaqaloqlar, pnevmoniya, leykotsitlar, limfotsitlar, immun tizim

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APATurabidinova, Gullola, Turdieva, Shohida, Турабидинова, Гуллола, Турдиева, Шохида, Turabidinova, Gullola, & Turdieva, Shohida (2026). IMMUNOHEMATOLOGICAL MARKERS OF INFLAMMATION IN FULL-TERM NEWBORNS WITH CONGENITAL PNEUMONIA. Халқаро илмий педиатрия журнали, 5(1), 1205-1212. https://doi.org/10.56121/2181-2926-2026-5-1-1205-1212
GOST (OAK)Turabidinova, Gullola va b. IMMUNOHEMATOLOGICAL MARKERS OF INFLAMMATION IN FULL-TERM NEWBORNS WITH CONGENITAL PNEUMONIA // Халқаро илмий педиатрия журнали. – 2026. – T. 5, № 1. – P. 1205-1212. – DOI: 10.56121/2181-2926-2026-5-1-1205-1212.
MLATurabidinova, Gullola, Turdieva, Shohida, Турабидинова, Гуллола, Турдиева, Шохида, Turabidinova, Gullola, and Turdieva, Shohida. “IMMUNOHEMATOLOGICAL MARKERS OF INFLAMMATION IN FULL-TERM NEWBORNS WITH CONGENITAL PNEUMONIA.” Халқаро илмий педиатрия журнали, 5(1), 1205-1212, 2026. https://doi.org/10.56121/2181-2926-2026-5-1-1205-1212
ChicagoTurabidinova, Gullola, Turdieva, Shohida, Турабидинова, Гуллола, Турдиева, Шохида, Turabidinova, Gullola, and Turdieva, Shohida. “IMMUNOHEMATOLOGICAL MARKERS OF INFLAMMATION IN FULL-TERM NEWBORNS WITH CONGENITAL PNEUMONIA.” Халқаро илмий педиатрия журнали, 5(1), 1205-1212 (2026). https://doi.org/10.56121/2181-2926-2026-5-1-1205-1212
HarvardTurabidinova, Gullola, Turdieva, Shohida, Турабидинова, Гуллола, Турдиева, Шохида, Turabidinova, Gullola, and Turdieva, Shohida (2026) ‘IMMUNOHEMATOLOGICAL MARKERS OF INFLAMMATION IN FULL-TERM NEWBORNS WITH CONGENITAL PNEUMONIA’, Халқаро илмий педиатрия журнали, 5(1), 1205-1212. https://doi.org/10.56121/2181-2926-2026-5-1-1205-1212
BibTeX
@article{turabidinovagullola2026,
  title = {IMMUNOHEMATOLOGICAL MARKERS OF INFLAMMATION IN FULL-TERM NEWBORNS WITH CONGENITAL PNEUMONIA},
  author = {Turabidinova, Gullola and Turdieva, Shohida and Турабидинова, Гуллола and Турдиева, Шохида and Turabidinova, Gullola and Turdieva, Shohida},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2026},
  volume = {5},
  number = {1},
  pages = {1205-1212},
  doi = {10.56121/2181-2926-2026-5-1-1205-1212},
  url = {https://doi.org/10.56121/2181-2926-2026-5-1-1205-1212}
}

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