This study aims to evaluate the significance of the WHOQOL-BREF questionnaire, a tool for assessing quality of life, and the biomarker brain-derived neurotrophic factor (BDNF) in patients with type 2 diabetes mellitus (T2DM) complicated by chronic kidney disease (CKD) who are receiving hemodialysis. A total of 90 patients with T2DM and stage III chronic renal failure (CRF) undergoing programmed hemodialysis were examined between January 1, 2019, and December 31, 2020. These patients were divided into three groups based on the severity of chronic cerebral ischemia (CCI). The results showed that as the degree of CCI increased, serum levels of BDNF decreased significantly compared to the control group. Additionally, significant correlations were found between WHOQOL-BREF scores and various clinical, laboratory, and instrumental parameters, including the duration of the disease, fasting blood glucose, glycated hemoglobin levels, BDNF, and blood flow velocity in the carotid and vertebral arteries. The study highlights the importance of the WHOQOL-BREF questionnaire in assessing the quality of life in this patient population and identifies BDNF as a valuable marker for brain ischemia in T2DM patients undergoing hemodialysis.
| Mualliflar | Kholikov , Alisher, Холиков , Алишер, Xoliqov , Alisher |
|---|---|
| Jurnal | Жамият ва инновациялар / Общество и инновации / Society and innovations |
| Nashriyot | In Science МЧЖ |
| ISSN | 2181-1415 |
| Nashr sanasi | 2024-09-25 |
| Jild | 5 |
| Son | 9/S |
| Betlar | 92-98 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| DOI | 10.47689/2181-1415-vol5-iss9/s-pp92-98 |
| Indeksga qo‘shilgan | 2026-08-26 |
DOI: 10.47689/2181-1415-vol5-iss9/s-pp92-98 · Maqolaning asl sahifasi
quality of life, WHOQOL-BREFis. BNDF, hemodialysis, качество жизни, WHOQOL-BREFis. BNDF, гемодиализ, hayot sifati, WHOQOL-BREFis. BNDF, gemodializ
| APA | Kholikov , Alisher, Холиков , Алишер, & Xoliqov , Alisher (2024). The importance of the questionnaire WHOQOL-BREF and neuromarker BNDF in patients with type 2 diabetes mellitus on hemodialysis in the assessment of the degree of brain ischemia. Жамият ва инновациялар / Общество и инновации / Society and innovations, 5(9/S), 92-98. https://doi.org/10.47689/2181-1415-vol5-iss9/s-pp92-98 |
|---|---|
| GOST (OAK) | Kholikov , Alisher, Холиков , Алишер, Xoliqov , Alisher The importance of the questionnaire WHOQOL-BREF and neuromarker BNDF in patients with type 2 diabetes mellitus on hemodialysis in the assessment of the degree of brain ischemia // Жамият ва инновациялар / Общество и инновации / Society and innovations. – 2024. – T. 5, № 9/S. – P. 92-98. – DOI: 10.47689/2181-1415-vol5-iss9/s-pp92-98. |
| MLA | Kholikov , Alisher, Холиков , Алишер, and Xoliqov , Alisher. “The importance of the questionnaire WHOQOL-BREF and neuromarker BNDF in patients with type 2 diabetes mellitus on hemodialysis in the assessment of the degree of brain ischemia.” Жамият ва инновациялар / Общество и инновации / Society and innovations, 5(9/S), 92-98, 2024. https://doi.org/10.47689/2181-1415-vol5-iss9/s-pp92-98 |
| Chicago | Kholikov , Alisher, Холиков , Алишер, and Xoliqov , Alisher. “The importance of the questionnaire WHOQOL-BREF and neuromarker BNDF in patients with type 2 diabetes mellitus on hemodialysis in the assessment of the degree of brain ischemia.” Жамият ва инновациялар / Общество и инновации / Society and innovations, 5(9/S), 92-98 (2024). https://doi.org/10.47689/2181-1415-vol5-iss9/s-pp92-98 |
| Harvard | Kholikov , Alisher, Холиков , Алишер, and Xoliqov , Alisher (2024) ‘The importance of the questionnaire WHOQOL-BREF and neuromarker BNDF in patients with type 2 diabetes mellitus on hemodialysis in the assessment of the degree of brain ischemia’, Жамият ва инновациялар / Общество и инновации / Society and innovations, 5(9/S), 92-98. https://doi.org/10.47689/2181-1415-vol5-iss9/s-pp92-98 |
| BibTeX | @article{kholikovalisher2024,
title = {The importance of the questionnaire WHOQOL-BREF and neuromarker BNDF in patients with type 2 diabetes mellitus on hemodialysis in the assessment of the degree of brain ischemia},
author = {Kholikov , Alisher and Холиков , Алишер and Xoliqov , Alisher},
journal = {Жамият ва инновациялар / Общество и инновации / Society and innovations},
year = {2024},
volume = {5},
number = {9/S},
pages = {92-98},
doi = {10.47689/2181-1415-vol5-iss9/s-pp92-98},
url = {https://doi.org/10.47689/2181-1415-vol5-iss9/s-pp92-98}
} |
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