Improving diagnostic and therapeutic approaches to giardiasis in children

Khafizova, Zemfira, Хафизова, Земфира, Khafizova, Zemfira

Халқаро илмий педиатрия журнали · 2026-yil

Annotatsiya

Background: Giardiasis remains one of the most common intestinal protozoal infections in children and continues to pose important diagnostic and therapeutic challenges because of intermittent cyst excretion, overlap with other gastrointestinal disorders, and frequent relapse after standard short-course treatment. Aim: To improve the diagnostic algorithm and optimize treatment strategies for giardiasis in pediatric patients. Methods: A prospective clinical study included 105 children aged 5-13 years. Diagnostic verification was performed using clinical assessment, stool microscopy, repeated coproscopy, and enzyme-linked immunosorbent assay (ELISA). In the therapeutic phase, 60 patients with confirmed mono-giardiasis were treated using three different regimens: metronidazole plus nifuroxazide, albendazole monotherapy, and a structured three-stage complex therapy. Results: Giardiasis as mono-infection or combined invasion was identified in 80.0% of examined children. ELISA was positive in 89.0% of cases but yielded 8.9% false-positive results. A single coproscopic examination detected giardiasis in only 55.5% of infected children, whereas repeated stool examination performed 3-5 times over 2 weeks reached 100% detection among children with positive ELISA and verified infection. The best treatment outcome was observed in the three-stage group, with 91.7% eradication after one course and only 2.5% recurrence after 12 weeks. Conclusion: ELISA is useful as a screening method but should be combined with repeated coproscopy for definitive diagnosis. A stepwise therapeutic approach incorporating antispasmodics, ursodeoxycholic acid, lactulose, and albendazole appears to be the most effective strategy for eradication and prevention of recurrence.

Maqola ma’lumotlari
MualliflarKhafizova, Zemfira, Хафизова, Земфира, Khafizova, Zemfira
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926
Nashr sanasi2026-10-28
Jild5
Son5
Betlar1466-1469
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2026-5-5-1466-1469
Indeksga qo‘shilgan2026-10-29

DOI: 10.56121/2181-2926-2026-5-5-1466-1469 · Maqolaning asl sahifasi

Kalit so‘zlar

giardiasis, children, diagnostics, ELISA, coproscopy, albendazole, ursodeoxycholic acid, recurrence prevention, лямблиоз, дети, диагностика, ИФА, копроскопия, альбендазол, урсодезоксихолевая кислота, профилактика рецидивов, giardiaz, bolalar, diagnostika, ELISA, koproskopi, albendazol, ursodeoksixol kislotasi, qaytalanishning oldini olish

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAKhafizova, Zemfira, Хафизова, Земфира, & Khafizova, Zemfira (2026). Improving diagnostic and therapeutic approaches to giardiasis in children. Халқаро илмий педиатрия журнали, 5(5), 1466-1469. https://doi.org/10.56121/2181-2926-2026-5-5-1466-1469
GOST (OAK)Khafizova, Zemfira, Хафизова, Земфира, Khafizova, Zemfira Improving diagnostic and therapeutic approaches to giardiasis in children // Халқаро илмий педиатрия журнали. – 2026. – T. 5, № 5. – P. 1466-1469. – DOI: 10.56121/2181-2926-2026-5-5-1466-1469.
MLAKhafizova, Zemfira, Хафизова, Земфира, and Khafizova, Zemfira. “Improving diagnostic and therapeutic approaches to giardiasis in children.” Халқаро илмий педиатрия журнали, 5(5), 1466-1469, 2026. https://doi.org/10.56121/2181-2926-2026-5-5-1466-1469
ChicagoKhafizova, Zemfira, Хафизова, Земфира, and Khafizova, Zemfira. “Improving diagnostic and therapeutic approaches to giardiasis in children.” Халқаро илмий педиатрия журнали, 5(5), 1466-1469 (2026). https://doi.org/10.56121/2181-2926-2026-5-5-1466-1469
HarvardKhafizova, Zemfira, Хафизова, Земфира, and Khafizova, Zemfira (2026) ‘Improving diagnostic and therapeutic approaches to giardiasis in children’, Халқаро илмий педиатрия журнали, 5(5), 1466-1469. https://doi.org/10.56121/2181-2926-2026-5-5-1466-1469
BibTeX
@article{khafizovazemfira2026,
  title = {Improving diagnostic and therapeutic approaches to giardiasis in children},
  author = {Khafizova, Zemfira and Хафизова, Земфира and Khafizova, Zemfira},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2026},
  volume = {5},
  number = {5},
  pages = {1466-1469},
  doi = {10.56121/2181-2926-2026-5-5-1466-1469},
  url = {https://doi.org/10.56121/2181-2926-2026-5-5-1466-1469}
}

Boshqa maqola uchun iqtibos tayyorlash

Халқаро илмий педиатрия журнали jurnalidan boshqa maqolalar

Халқаро илмий педиатрия журнали — barcha maqolalar · 2026-yil arxivi

Khafizova, Zemfira — boshqa maqolalari

Tibbiyot sohasidagi boshqa maqolalar

Tibbiyot sohasidagi OAK jurnallari