Abstract: Juvenile rheumatoid arthritis (JRA) of preschool age is represented in the literature by a few observations[1,2]. The purpose of this work was to study the clinical and laboratory signs of the initial period of JRA in 60 children under the age of 7 years, as well as the tactics of rational therapy and the results of follow-up observation of sick preschool children treated in a hospital during 2015-2021. Material and methods: Among the observed patients, the disease began in the majority (32) at the 7th year of life, in 11 - before the age of 5 years, in 17 - at 3 years. Subacute onset of the disease, characteristic of preschool children, was noted in 36 (60%), which was due to the development of the articular form in the majority of patients (39, or 65%). Among them, the majority were children with the most benign variants - oligoarthritis (19) and monoarthritis (5); 15 patients had multiple joint damage. On the contrary, among patients with the articular-visceral form (20, or 33.3%), the most severe variants with polyvisceritis initially prevailed in most cases - allergic septic syndrome (in 10) and Still's syndrome (in 5). Results: Our observations revealed a certain dependence of the nature of the activity of JRA and the development of destructive changes in the joints on the timing of the start of targeted therapy. Conclusion: therefore, targeted complex long-term therapy of RA in preschool age not only leads to a persistent decrease in activity, stabilization of the process in the majority children, but also avoids the use of corticosteroids, and also promotes reparative changes and rehabilitation of a significant part of patients (43%).
| Mualliflar | Khafizova, Zemfira, Хафизова, Земфира, Xafizova, Zemfira |
|---|---|
| Jurnal | Халқаро илмий педиатрия журнали |
| Nashr sanasi | 2023-09-30 |
| Jild | 2 |
| Son | 9 |
| Betlar | 320-324 |
| Til | Ingliz |
| DOI | 10.56121/2181-2926-2023-2-9-320-324 |
DOI: 10.56121/2181-2926-2023-2-9-320-324 · Maqolaning asl sahifasi
ювенильный ревматоидный артрит, терапия, катамнез, дети, children, juvenile rheumatoid arthritis, therapy, follow-up, bolalar, balog'atga etmagan revmatoid artrit, terapiya, kuzatuv
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