Principles of timely complex therapy for rheumatoid arthritis in preschool children

Khafizova, Zemfira, Хафизова, Земфира, Xafizova, Zemfira

Халқаро илмий педиатрия журнали · 2023-yil

Annotatsiya

Abstract: Juvenile rheumatoid arthritis (JRA) of preschool age is represented in the literature by a few observations[1,2]. The purpose of this work was to study the clinical and laboratory signs of the initial period of JRA in 60 children under the age of 7 years, as well as the tactics of rational therapy and the results of follow-up observation of sick preschool children treated in a hospital during 2015-2021. Material and methods: Among the observed patients, the disease began in the majority (32) at the 7th year of life, in 11 - before the age of 5 years, in 17 - at 3 years. Subacute onset of the disease, characteristic of preschool children, was noted in 36 (60%), which was due to the development of the articular form in the majority of patients (39, or 65%). Among them, the majority were children with the most benign variants - oligoarthritis (19) and monoarthritis (5); 15 patients had multiple joint damage. On the contrary, among patients with the articular-visceral form (20, or 33.3%), the most severe variants with polyvisceritis initially prevailed in most cases - allergic septic syndrome (in 10) and Still's syndrome (in 5). Results: Our observations revealed a certain dependence of the nature of the activity of JRA and the development of destructive changes in the joints on the timing of the start of targeted therapy. Conclusion: therefore, targeted complex long-term therapy of RA in preschool age not only leads to a persistent decrease in activity, stabilization of the process in the majority children, but also avoids the use of corticosteroids, and also promotes reparative changes and rehabilitation of a significant part of patients (43%).

Maqola ma’lumotlari
MualliflarKhafizova, Zemfira, Хафизова, Земфира, Xafizova, Zemfira
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2023-09-30
Jild2
Son9
Betlar320-324
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2023-2-9-320-324
Indeksga qo‘shilgan2026-08-26

Kalit so‘zlar

ювенильный ревматоидный артрит, терапия, катамнез, дети, children, juvenile rheumatoid arthritis, therapy, follow-up, bolalar, balog'atga etmagan revmatoid artrit, terapiya, kuzatuv

Ilmiy soha

Iqtibos keltirish

APAKhafizova, Zemfira, Хафизова, Земфира, & Xafizova, Zemfira (2023). PRINCIPLES OF TIMELY COMPLEX THERAPY FOR RHEUMATOID ARTHRITIS IN PRESCHOOL CHILDREN. Халқаро илмий педиатрия журнали, 2(9), 320-324. https://doi.org/10.56121/2181-2926-2023-2-9-320-324
GOST (OAK)Khafizova, Zemfira, Хафизова, Земфира, Xafizova, Zemfira PRINCIPLES OF TIMELY COMPLEX THERAPY FOR RHEUMATOID ARTHRITIS IN PRESCHOOL CHILDREN // Халқаро илмий педиатрия журнали. – 2023. – T. 2, № 9. – P. 320-324. – DOI: 10.56121/2181-2926-2023-2-9-320-324.
MLAKhafizova, Zemfira, Хафизова, Земфира, and Xafizova, Zemfira. “PRINCIPLES OF TIMELY COMPLEX THERAPY FOR RHEUMATOID ARTHRITIS IN PRESCHOOL CHILDREN.” Халқаро илмий педиатрия журнали, 2(9), 320-324, 2023. https://doi.org/10.56121/2181-2926-2023-2-9-320-324
ChicagoKhafizova, Zemfira, Хафизова, Земфира, and Xafizova, Zemfira. “PRINCIPLES OF TIMELY COMPLEX THERAPY FOR RHEUMATOID ARTHRITIS IN PRESCHOOL CHILDREN.” Халқаро илмий педиатрия журнали, 2(9), 320-324 (2023). https://doi.org/10.56121/2181-2926-2023-2-9-320-324
HarvardKhafizova, Zemfira, Хафизова, Земфира, and Xafizova, Zemfira (2023) ‘PRINCIPLES OF TIMELY COMPLEX THERAPY FOR RHEUMATOID ARTHRITIS IN PRESCHOOL CHILDREN’, Халқаро илмий педиатрия журнали, 2(9), 320-324. https://doi.org/10.56121/2181-2926-2023-2-9-320-324
BibTeX
@article{khafizovazemfira2023,
  title = {PRINCIPLES OF TIMELY COMPLEX THERAPY FOR RHEUMATOID ARTHRITIS IN PRESCHOOL CHILDREN},
  author = {Khafizova, Zemfira and Хафизова, Земфира and Xafizova, Zemfira},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2023},
  volume = {2},
  number = {9},
  pages = {320-324},
  doi = {10.56121/2181-2926-2023-2-9-320-324},
  url = {https://doi.org/10.56121/2181-2926-2023-2-9-320-324}
}

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