Purpose of the study: to determine the relationship between the levels of cytokines (IL-1β, IL-6; IL-10, TNF-α) and the clinical course of coronary artery disease in COPD. Material and methods: this study is based on the results of observation of patients with coronary artery disease hospitalized in the period from 2021-2022. in the departments of somatic resuscitation, emergency therapy No. 1, 2 of the Samarkand Branch of the Republican Scientific Center for Emergency Medical Care (SF RSCEMC). The study involved 88 patients with coronary artery disease and COPD, which were divided into 2 groups depending on gender. As a result of the study, the relationship between the concentration of pro-inflammatory interleukins and severe courses of coronary artery disease with COPD was revealed, which allows us to recommend its use as an additional laboratory indicator for these pathologies, and allows us to identify groups with a low and high risk of developing various complications. At the same time, in patients with high expression of TNF-α, IL-6 and IL-1β in the blood, a complicated course of the disease is predicted. Early identification of categories of patients with coronary artery disease and COPD with an increased risk of complications will allow the use of more active methods of treatment (medication and/or surgery) for such patients.
| Mualliflar | Ташкенбаева Элеонора Негматовна, Хасанжанова Фарида Одыловна, Худойназаров Далер Анвар углы, Худойназаров Далер Анвар углы, Усаров Шохрух Абдувахоб углы |
|---|---|
| Jurnal | Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali |
| Nashr sanasi | 2023-06-12 |
| Jild | 4 |
| Son | 1 |
| Til | Rus |
ИБС, ХОБЛ, провоспалительный и противовоспалительный интерлейкин, HD, COPD, pro-inflammatory and anti-inflammatory interleukin, YuIK, O’SOK, yallig'lanishga qarshi va yallig'lanishga qarshi interleykin
Optimal related kidney transplant donors were predominantly overweight, which correlated with the intensity of subclinical inflammation and endotoxemia. An increase in IL-6 and CRP in donors correlated with both age and…
The effects of menopause and hormone therapy on cytokine production and plasma levels are equally complex. Aging is associated with increased levels of circulating inflammatory cytokines, especially IL-6 and TNFa, a…
The present study is devoted to assessing the prevalence and clinical and diagnostic aspects of connective tissue dysplasia in Samarkand and Jizzakh regions, as well as studying the course of the disease depending on…
Congenital heart defects (CHDs) are an important problem in pediatrics due to their high prevalence and the need for early surgical correction due to significant health problems and disability in children. according to…
Portal hypertension can be caused by a variety of conditions. It often manifests as bleeding from varices in the oesophagus. The approach to acute variceal bleeding in children is a stepwise progression from least…
Purpose: to evaluate indicators of psychological status, health level and physical performance in individuals with alimentary obesity (AO) and high cardiovascular risk (CVR). Material and methods. 99 individuals with…
Chronic heart failure (CHF), being an outcome of cardiovascular continuum, leads to worsening of the course not only of the disease cause, but also to its decompensation, rehospitalizations, which leads to difficulties…
Chronic Obstructive Pulmonary Disease (COPD) is a disease of the respiratory system that develops continuously and has an increasing mortality rate. The purpose of the study is to study the characteristics of the immune…
The problem of comorbidity is widely discussed in the current medical literature. Its role in rheumatic diseases is particularly interesting because of its multifactorial nature and the involvement of a wide range of…
The aim: to study the G894T gene polymorphism of the NOS3 gene on the risk of developing resistant arterial hypertension (AH) in Uzbek population. Materials and Methods: The study included 176 patients with I-III degree…
Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali — barcha maqolalar