The primary cause of hypoxic-ischemic brain injury is widely recognized as the restriction of both oxygen supply and essential oxidative substrates necessary for cellular function. This understanding is supported by existing research ([3,4]). The most critical damage to brain cells occurs 2-6-48 hours after birth due to oxidative stress. This process is triggered by the resumption of blood flow to the brain following a period of oxygen deprivation (perfusion deficit). The reintroduction of highly oxygenated blood leads to an overproduction of harmful free radicals, contributing to cell damage. A study involving 60 premature infants who experienced asphyxia during birth was conducted at the Samarkand Regional Perinatal Centre and the Neonatal Intensive Care Unit of the Samarkand Multidisciplinary Children's Research Medical Centre. These infants were closely monitored to observe the effects of oxidative stress on brain tissue.
| Mualliflar | Файзуллаева Хилола Бахроновна |
|---|---|
| Jurnal | Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) |
| Nashr sanasi | 2025-05-07 |
| Jild | 6 |
| Son | 1 |
| Til | Ingliz |
асфиксия, новорожденные, церебропротектор, цитофлавин, asphyxia, newborns, cerebroprotector, Cytoflavin, asfiksiya, yangi tug'ilgan chaqaloqlar, serebroprotektor, sitoflavin
Acute abdominal pain should always be evaluated quickly and accurately due to the possibility of urgent surgical intervention. We report a case of a woman with ovarian apoplexy while taking Clofit Citrate. The patient…
The choice of the uterine suturing method after a cesarean section plays an important role in reducing the risk of complications and affects subsequent reproductive outcomes. A study was conducted on 496 women aged 18…
A study was conducted on 496 women aged 18 to 42 years who underwent a cesarean section. Based on the uterine closure method, all patients were divided into two groups: Group 1 – 240 (48%) women who underwent modified…
Uterine fibroids are a common benign, reactive tumor – like formation of smooth muscle elements with their subsequent fibrosis under conditions of tissue hypoxia. In some cases, at the very beginning of the development…
Acute respiratory viral infections have been a pressing problem at various times in human history. The emergence of the COVID-19 pandemic in the 21st century has shown that this infection has had a serious impact on the…
In severe iron deficiency anemia, depending on the reactivity of the body, a decrease in heart rate variability, against the background of a decrease in the triangular index, parasympathetic, and humoral components…