Immuno-biochemical and histological characteristics of uterine leiomyoma

Хамидова Шахло Шариповна, Наврузова Шакар Истамовна, Ихтиярова Гулчеҳра Акмаловна

Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2024-yil

Annotatsiya

Uterine leiomyoma is a common gynecological condition that affects women of various age groups, particularly those in their reproductive years. To explore the clinical characteristics and underlying pathophysiological mechanisms of this condition, a comprehensive clinical study was conducted involving 120 women diagnosed with uterine leiomyoma, aged 20 to 49 years. The majority of the participants were women aged 40 to 49 years (90 individuals), with a significant predominance of Uzbek nationality (106 women, 88.3%). Educational and occupational analyses revealed a higher prevalence of this pathology among women with secondary specialized education (71.6%) and housewives (51.6%). The study also highlighted the complex obstetric history of the participants, with 14.2% reporting spontaneous miscarriages, 17.5% experiencing non-developing pregnancies, and 2.5% having a history of ectopic pregnancies. The primary complaints among the patients included hyperpolymenorrhea (51.6%), pelvic pain and algomenorrhea (36.7%), menstrual irregularities (59.2%), dyspareunia (27.5%), and infertility (22.5%). Statistical analysis of the data involved both parametric and non-parametric methods, revealing significant clinical and laboratory findings. For instance, patients with uterine leiomyoma exhibited elevated levels of pro-inflammatory cytokines, such as IL-6 and TNF-α, and growth factors like TGF-β2 and VEGF, which are indicative of active inflammatory and proliferative processes.

Maqola ma’lumotlari
MualliflarХамидова Шахло Шариповна, Наврузова Шакар Истамовна, Ихтиярова Гулчеҳра Акмаловна
JurnalJournal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)
NashriyotСамарқанд давлат тиббиёт университети
ISSN2017-2021
Nashr sanasi2024-10-09
Jild5
Son3
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

лейомиома матки, самопроизвольные выкидыши, внематочные беременности, гиперполи менорея, боли в области таза, алгоменорея, нарушения менструального цикла, диспареуния, цитокины, uterine leiomyoma, spontaneous miscarriages, ectopic pregnancies, hyperpolymenorrhea, pelvic pain, algomenorrhea, menstrual irregularities, dyspareunia, cytokines, bachadon leyomiomasi, spontan tushish, ektopik homiladorlik, giperpoli menoreya, chanoq sohasida og‘riq, algomenoreya, hayzning nomutanosibligi, dispareuniya, sitokinlar

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Iqtibos keltirish

APAХамидова Шахло Шариповна, Наврузова Шакар Истамовна, & Ихтиярова Гулчеҳра Акмаловна (2024). IMMUNO-BIOCHEMICAL AND HISTOLOGICAL CHARACTERISTICS OF UTERINE LEIOMYOMA. Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 5(3). https://tadqiqot.uz/index.php/uro/article/view/10248
GOST (OAK)Хамидова Шахло Шариповна, Наврузова Шакар Истамовна, Ихтиярова Гулчеҳра Акмаловна IMMUNO-BIOCHEMICAL AND HISTOLOGICAL CHARACTERISTICS OF UTERINE LEIOMYOMA // Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали). – 2024. – T. 5, № 3.
MLAХамидова Шахло Шариповна, Наврузова Шакар Истамовна, and Ихтиярова Гулчеҳра Акмаловна. “IMMUNO-BIOCHEMICAL AND HISTOLOGICAL CHARACTERISTICS OF UTERINE LEIOMYOMA.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 5(3), 2024. https://tadqiqot.uz/index.php/uro/article/view/10248
ChicagoХамидова Шахло Шариповна, Наврузова Шакар Истамовна, and Ихтиярова Гулчеҳра Акмаловна. “IMMUNO-BIOCHEMICAL AND HISTOLOGICAL CHARACTERISTICS OF UTERINE LEIOMYOMA.” Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 5(3) (2024). https://tadqiqot.uz/index.php/uro/article/view/10248
HarvardХамидова Шахло Шариповна, Наврузова Шакар Истамовна, and Ихтиярова Гулчеҳра Акмаловна (2024) ‘IMMUNO-BIOCHEMICAL AND HISTOLOGICAL CHARACTERISTICS OF UTERINE LEIOMYOMA’, Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали), 5(3). https://tadqiqot.uz/index.php/uro/article/view/10248
BibTeX
@article{article2024,
  title = {IMMUNO-BIOCHEMICAL AND HISTOLOGICAL CHARACTERISTICS OF UTERINE LEIOMYOMA},
  author = {Хамидова Шахло Шариповна and Наврузова Шакар Истамовна and Ихтиярова Гулчеҳра Акмаловна},
  journal = {Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали)},
  year = {2024},
  volume = {5},
  number = {3},
  url = {https://tadqiqot.uz/index.php/uro/article/view/10248}
}

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