Objective: to study the state of the cytokine link in women with ovarian hyperandrogenism. Material and methods. The study involved 55 women of reproductive age with an established diagnosis of ovarian hyperandrogenism. The control group consisted of 35 practically healthy women of reproductive age. Serum cytokine levels were determined by ELISA, in accordance with the manufacturer's recommendations. Results: A significant increase in the levels of proinflammatory cytokines IL-6, IL-8 and IL-17A was found in women with hyperandrogenism compared to the control group. These changes may play a key role in the pathogenesis of the disease, affecting metabolic and reproductive functions. Further research is needed to develop therapeutic strategies aimed at reducing inflammation and improving the condition of patients
Якуббоева Шахноза Умидовна, Собирова Мохичеxра Расулджоновна, Рузиева Нодира Хакимовна · Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2024-10-09
In recent years, the number of teenage girls engaged in professional sports is increasing and the impact of this activity on the reproductive health of girls, especially the reproductive system of teenage girls, i.e…
Эргашев Бахтиёр Бердалиевич, Хамроев Улугбек Абдурашидович, Абдуганиев Абужамил Абдугаффорович · Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2024-10-09
The first experience with laparoscopic correction of duodenal obstruction in newborns was presented in 2001, but there is still debate about the preferred method of surgical correction. The article presents the…
Мирахмедова Шахзода Тургун кизи, Каюмова Дилрабо Толмасовна · Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2024-10-09
The relevance of the study of reproductive health and risk assessment of polycystic ovary syndrome (PCOS) is related to the fact that this disease is a common cause of infertility, and is also a global somatic health…
Эргашев Бахтиёр Бердалиевич, Эгамназаров Нурбек Куйлиевич · Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2024-10-09
Based on a comprehensive study of 41 children with bladder exstrophy (BE) at the age of 1 day to 1 year. The scheme of the proposed phasing of the operative correction of this defect includes an early age approach (1…
Абдикулова Нигора Хасановна · Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2025-02-09
Хан-Ходжаева Сохибахон Анваровна, Бабаджанов Ойбек Абдужаббарович · Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2024-10-09
Psoriasis is a chronic inflammatory skin disease characterized by keratinocyte hyperplasia and impaired immune response. The disease affects approximately 2-3% of the world's population and is associated with marked…
Агабабян Лариса Рубеновна, Усманкулова Хабиба Мизробжоновна · Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2025-02-09
Хамидова Шахло Шариповна, Наврузова Шакар Истамовна, Ихтиярова Гулчеҳра Акмаловна · Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2024-10-09
Uterine leiomyoma is a common gynecological condition that affects women of various age groups, particularly those in their reproductive years. To explore the clinical characteristics and underlying pathophysiological…
Каттаходжаева Махмуда Хамдамовна, Абдуллаева Лола Сайфуллаевна · Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2025-02-09
Фазилова Махшура Олимжановна · Journal of reproductive health and uro-nephrology research (Репродуктив саломатлик ва уро-нефрологик тадқиқотлар журнали) · 2024-10-09
Preconception preparation is an important aspect in pregnancy planning, especially for women who have a history of fetal loss, including non-developing pregnancies. A total of 280 patients were examined and…