Plasma protein-C is a naturally occurring anticoagulant and its deficiency, either homozygous or heterozygous, predisposes the individual to a state of thrombosis, particularly venous thromboembolism, and manifests as deep venous thrombosis (DVT), pulmonary embolism (PE), myocardial infarction (MI), or stroke. Protein C exerts anticoagulatory effects by inactivating factors V and VIII. Hereditary protein C deficiency is inherited as an autosomal dominant disorder. Homozygous individuals usually develop purpura fulminans as newborns; heterozygous protein C-deficient individuals are at increased risk for venous thrombosis and pulmonary embolism. We describe a young patient with protein-C deficiency who experienced recurrent pulmonary embolism as well as deep vein thrombosis due to thrombotic occlusion without underlying major risk factors. Pulse Vol.16, 2024 P: 43-46
| Mualliflar | Kaniz Fatema, Borhan Uddin Ahmed, Mohammad Mahfuzur Rahman |
|---|---|
| Jurnal | PULSE |
| Nashr sanasi | 2024-10-21 |
| Jild | 16 |
| Son | 1 |
| Betlar | 43-46 |
| Til | en |
| DOI | 10.3329/pulse.v16i1.77071 |
DOI: 10.3329/pulse.v16i1.77071 · Maqolaning asl sahifasi · PDF
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