Presence of Microvascular Dysfunction and CHA2DS2-VASc Score in Patients with ST-Segment Myocardial Infarction after Primary Percutaneous Coronary Intervention

Ragab A. Mahfouz, Marwa Gad, Mohamed Arab, Moei-E. deen Abulfotouh

PULSE · 2021-yil

Annotatsiya

Objective: We aimed to investigate the relation between CHA2DS2-VASc score and microvascular dysfunction (MVD) assessed by the index of microvascular resistance (IMR) immediately after primary percutaneous intervention (PPCI) for patients with ST-segment elevation myocardial infarction (STEMI). Subjects and Methods: The study included 115 consecutive patients with STEMI who underwent successful PPCI. Angiographic results of reperfusion were inspected to evaluate the association of high CHA2DS2-VASc score and IMR. Also, we assessed echocardiographic changes with respect to CHA2DS2-VASc score. Results: Subjects were stratified into 2 groups based on IMR </≥ 40 U; 72 patients (62.6) with IMR <40 U and 43 patients (37.4) with IMR ≥40 U. Patients with IMR ≥40 U had higher CHA2DS2-VASc score (p < 0.001). CHA2DS2-VASc score was significantly correlated with increased left atrial volume index, diastolic dysfunction, wall motion score index, and inversely correlated left ventricular ejection. Moreover, CHA2DS2-VASc score was strongly correlated with IMR (p < 0.001). At multivariate analysis, low systolic blood pressure, stent diameter, and CHA2DS2-VASc score were associated with MVD. Besides, CHA2DS2-VASc score ≥4 was the optimal value in predicting MVD (IMR ≥40) in STEMI patients. Conclusions: The data of the current study point out that increased CHA2DS2-VASc score, lower systolic blood pressure <90 mm Hg, and stent diameter are associated with increased incidence of MVD (increased IMR) after PPCI of STEMI. We suggest that the CHA2DS2-VASc score may be a simple, inexpensive useful risk score for the prediction of MVD risk after PPCI for STEMI patients.

Maqola ma’lumotlari
MualliflarRagab A. Mahfouz, Marwa Gad, Mohamed Arab, Moei-E. deen Abulfotouh
JurnalPULSE
NashriyotPROFI университетининг
ISSN2074-1855, 2235-8668
Nashr sanasi2021-01-01
Jild9
Son3-4
Betlar125-132
TilIngliz
Ilmiy sohaPsixologiya
DOI10.1159/000520074
Indeksga qo‘shilgan2026-09-02

Ilmiy soha

Iqtibos keltirish

APARagab A. Mahfouz, Marwa Gad, Mohamed Arab, & Moei-E. deen Abulfotouh (2021). Presence of Microvascular Dysfunction and CHA2DS2-VASc Score in Patients with ST-Segment Myocardial Infarction after Primary Percutaneous Coronary Intervention. PULSE, 9(3-4), 125-132. https://doi.org/10.1159/000520074
GOST (OAK)Ragab A. Mahfouz va b. Presence of Microvascular Dysfunction and CHA2DS2-VASc Score in Patients with ST-Segment Myocardial Infarction after Primary Percutaneous Coronary Intervention // PULSE. – 2021. – T. 9, № 3-4. – P. 125-132. – DOI: 10.1159/000520074.
MLARagab A. Mahfouz, Marwa Gad, Mohamed Arab, and Moei-E. deen Abulfotouh. “Presence of Microvascular Dysfunction and CHA2DS2-VASc Score in Patients with ST-Segment Myocardial Infarction after Primary Percutaneous Coronary Intervention.” PULSE, 9(3-4), 125-132, 2021. https://doi.org/10.1159/000520074
ChicagoRagab A. Mahfouz, Marwa Gad, Mohamed Arab, and Moei-E. deen Abulfotouh. “Presence of Microvascular Dysfunction and CHA2DS2-VASc Score in Patients with ST-Segment Myocardial Infarction after Primary Percutaneous Coronary Intervention.” PULSE, 9(3-4), 125-132 (2021). https://doi.org/10.1159/000520074
HarvardRagab A. Mahfouz, Marwa Gad, Mohamed Arab, and Moei-E. deen Abulfotouh (2021) ‘Presence of Microvascular Dysfunction and CHA2DS2-VASc Score in Patients with ST-Segment Myocardial Infarction after Primary Percutaneous Coronary Intervention’, PULSE, 9(3-4), 125-132. https://doi.org/10.1159/000520074
BibTeX
@article{ragabamahfouz2021,
  title = {Presence of Microvascular Dysfunction and CHA2DS2-VASc Score in Patients with ST-Segment Myocardial Infarction after Primary Percutaneous Coronary Intervention},
  author = {Ragab A. Mahfouz and Marwa Gad and Mohamed Arab and Moei-E. deen Abulfotouh},
  journal = {PULSE},
  year = {2021},
  volume = {9},
  number = {3-4},
  pages = {125-132},
  doi = {10.1159/000520074},
  url = {https://doi.org/10.1159/000520074}
}

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