From Heartbreak to Heart Disease: A Narrative Review on Depression as an Adjunct to Cardiovascular Disease

Jahanzeb Malik, Hamid Sharif Khan, Faizan Younus, Muhammad Shoaib

PULSE · 2020-yil

Annotatsiya

Patients with cardiovascular disease (CVD) commonly have subclinical depression and are often delayed in their diagnosis. Literature suggests an increased association of depression and adverse cardiovascular events like myocardial infarction and heart failure. Prevalence of depression in developed countries is approximately 16.6%, and it confers higher cardiovascular mortality even after attrition bias and confounding factors are eliminated. Pharmacological and cognitive-behavioral therapy have been extensively studied, and are generally safe and effective in alleviating depressive symptoms in patients with CVD. However, their impact on cardiovascular outcomes is still unclear. Results of randomized controlled trials have shown antidepressants, especially selective serotonin reuptake inhibitors, to be safe and effective for healing a "broken heart." This review outlines the prevalence of depression in patients with CVD, the pathophysiological mechanism causing cardiovascular events with depression, and a link between depression and CVD. There is a wealth of literature explaining the precursor of CVD in depression, and like all chronic diseases, inflammation seems to be the culprit in this case as well.

Maqola ma’lumotlari
MualliflarJahanzeb Malik, Hamid Sharif Khan, Faizan Younus, Muhammad Shoaib
JurnalPULSE
NashriyotPROFI университетининг
ISSN2074-1855, 2235-8668
Nashr sanasi2020-01-01
Jild8
Son3-4
Betlar86-91
TilIngliz
Ilmiy sohaPsixologiya
DOI10.1159/000516415
Indeksga qo‘shilgan2026-09-02

Ilmiy soha

Iqtibos keltirish

APAJahanzeb Malik, Hamid Sharif Khan, Faizan Younus, & Muhammad Shoaib (2020). From Heartbreak to Heart Disease: A Narrative Review on Depression as an Adjunct to Cardiovascular Disease. PULSE, 8(3-4), 86-91. https://doi.org/10.1159/000516415
GOST (OAK)Jahanzeb Malik va b. From Heartbreak to Heart Disease: A Narrative Review on Depression as an Adjunct to Cardiovascular Disease // PULSE. – 2020. – T. 8, № 3-4. – P. 86-91. – DOI: 10.1159/000516415.
MLAJahanzeb Malik, Hamid Sharif Khan, Faizan Younus, and Muhammad Shoaib. “From Heartbreak to Heart Disease: A Narrative Review on Depression as an Adjunct to Cardiovascular Disease.” PULSE, 8(3-4), 86-91, 2020. https://doi.org/10.1159/000516415
ChicagoJahanzeb Malik, Hamid Sharif Khan, Faizan Younus, and Muhammad Shoaib. “From Heartbreak to Heart Disease: A Narrative Review on Depression as an Adjunct to Cardiovascular Disease.” PULSE, 8(3-4), 86-91 (2020). https://doi.org/10.1159/000516415
HarvardJahanzeb Malik, Hamid Sharif Khan, Faizan Younus, and Muhammad Shoaib (2020) ‘From Heartbreak to Heart Disease: A Narrative Review on Depression as an Adjunct to Cardiovascular Disease’, PULSE, 8(3-4), 86-91. https://doi.org/10.1159/000516415
BibTeX
@article{jahanzebmalik2020,
  title = {From Heartbreak to Heart Disease: A Narrative Review on Depression as an Adjunct to Cardiovascular Disease},
  author = {Jahanzeb Malik and Hamid Sharif Khan and Faizan Younus and Muhammad Shoaib},
  journal = {PULSE},
  year = {2020},
  volume = {8},
  number = {3-4},
  pages = {86-91},
  doi = {10.1159/000516415},
  url = {https://doi.org/10.1159/000516415}
}

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