Synthesis of novel tetracyclic THIENO[3,2-d]PYRIMIDINONES

Anvarjon Buronov, Azizbek Nasrullaev, Khurshed Bozorov, Nie Lifei, S. Kulmirzaeva, A. Ishankulov

Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi · 2025-yil

Annotatsiya

The synthesis of novel thieno[3,2-d]pyrimidine derivatives commenced with 5-bromo-2-chlorobenzonitrile with ethyl-2-mercaptoacetate, which yielded the compound AT-2. The addition of piperidin-2-one to the formed AT-2 and subsequent cyclization yielded the compound AR-05. Subsequently, the Suzuki cross-coupling reaction was employed to facilitate the formation of a carbon-carbon bond. The intermediate AR-05 was formed in an alkaline medium in a toluene/water mixture in the presence of arylboronic acid and a palladium catalyst, forming a new C-C bond. AR-27 was synthesized as the final product. The structure of the new compounds was studied by analyzing the results obtained through the investigation of their physical and physicochemical properties.

Maqola ma’lumotlari
MualliflarAnvarjon Buronov, Azizbek Nasrullaev, Khurshed Bozorov, Nie Lifei, S. Kulmirzaeva, A. Ishankulov
JurnalSamarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi
NashriyotСамарқанд давлат университети
ISSN2091-5446, 2181-1296
Nashr sanasi2025-03-29
Jild1
Son1
Betlar5-11
TilIngliz
Ilmiy sohaKimyo
DOI10.59251/2181-1296.2025.v1.149.2.3206
Indeksga qo‘shilgan2026-09-02

DOI: 10.59251/2181-1296.2025.v1.149.2.3206 · Maqolaning asl sahifasi

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Iqtibos keltirish

APAAnvarjon Buronov, Azizbek Nasrullaev, Khurshed Bozorov, Nie Lifei, S. Kulmirzaeva, & A. Ishankulov (2025). SYNTHESIS OF NOVEL TETRACYCLIC THIENO[3,2-d]PYRIMIDINONES. Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(1), 5-11. https://doi.org/10.59251/2181-1296.2025.v1.149.2.3206
GOST (OAK)Anvarjon Buronov va b. SYNTHESIS OF NOVEL TETRACYCLIC THIENO[3,2-d]PYRIMIDINONES // Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi. – 2025. – T. 1, № 1. – P. 5-11. – DOI: 10.59251/2181-1296.2025.v1.149.2.3206.
MLAAnvarjon Buronov, Azizbek Nasrullaev, Khurshed Bozorov, Nie Lifei, S. Kulmirzaeva, and A. Ishankulov. “SYNTHESIS OF NOVEL TETRACYCLIC THIENO[3,2-d]PYRIMIDINONES.” Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(1), 5-11, 2025. https://doi.org/10.59251/2181-1296.2025.v1.149.2.3206
ChicagoAnvarjon Buronov, Azizbek Nasrullaev, Khurshed Bozorov, Nie Lifei, S. Kulmirzaeva, and A. Ishankulov. “SYNTHESIS OF NOVEL TETRACYCLIC THIENO[3,2-d]PYRIMIDINONES.” Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(1), 5-11 (2025). https://doi.org/10.59251/2181-1296.2025.v1.149.2.3206
HarvardAnvarjon Buronov, Azizbek Nasrullaev, Khurshed Bozorov, Nie Lifei, S. Kulmirzaeva, and A. Ishankulov (2025) ‘SYNTHESIS OF NOVEL TETRACYCLIC THIENO[3,2-d]PYRIMIDINONES’, Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi, 1(1), 5-11. https://doi.org/10.59251/2181-1296.2025.v1.149.2.3206
BibTeX
@article{anvarjonburonov2025,
  title = {SYNTHESIS OF NOVEL TETRACYCLIC THIENO[3,2-d]PYRIMIDINONES},
  author = {Anvarjon Buronov and Azizbek Nasrullaev and Khurshed Bozorov and Nie Lifei and S. Kulmirzaeva and A. Ishankulov},
  journal = {Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi},
  year = {2025},
  volume = {1},
  number = {1},
  pages = {5-11},
  doi = {10.59251/2181-1296.2025.v1.149.2.3206},
  url = {https://doi.org/10.59251/2181-1296.2025.v1.149.2.3206}
}

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