Design of novel tricyclic arylidene THIENO[3,2- d]PYRIMIDINONES

Anvarjon, Buronov, Azizbek, Nasrullaev, Khurshed, Bozorov

Қўқон ДПИ. Илмий хабарлар · 2026-yil

Annotatsiya

A novel polycyclic arylidene thieno[3,2-d]pyrimidinone, (E)-5-(2,4- dimethoxybenzylidene)-3-methyl-6,7-dihydropyrrolo[1,2-a]thieno[3,2-d]pyrimidin-9(5H)- one (6a-b), was synthesized from ethyl 3-amino-4-methylthiophene-2-carboxylate (3) through a two-step cyclization sequence followed by condensation of the α-methylene moiety with an aromatic aldehyde. The synthetic strategy enabled sequential construction of the fused heterocyclic framework and subsequent introduction of an arylidene fragment at the reactive α-methylene position. The structures of the synthesized intermediates and target compound were characterized by 1H and 13C NMR spectroscopy and high-resolution mass spectrometry (HRMS). The obtained results demonstrate the applicability of this synthetic approach to the preparation of structurally differentiated polycyclic thieno[3,2- d]pyrimidinone derivatives.

Maqola ma’lumotlari
MualliflarAnvarjon, Buronov, Azizbek, Nasrullaev, Khurshed, Bozorov
JurnalҚўқон ДПИ. Илмий хабарлар
NashriyotҚўқон давлат педагогика институти
ISSN3030-3958
Nashr sanasi2026-10-10
Jild8
Son9
Betlar826-834
TilIngliz
Ilmiy sohaSan’atshunoslik
DOI10.70728/a.series.tab.v08.i09.107
Indeksga qo‘shilgan2026-10-11

DOI: 10.70728/a.series.tab.v08.i09.107 · Maqolaning asl sahifasi

Kalit so‘zlar

aromatic aldehyde, α-methylene condensation, cyclization, 2- pyrrolidinone, polycyclic thieno[3, 2-d]pyrimidinone.

Ilmiy soha

San’atshunoslik

Iqtibos keltirish

APAAnvarjon, Buronov, Azizbek, Nasrullaev, & Khurshed, Bozorov (2026). DESIGN OF NOVEL TRICYCLIC ARYLIDENE THIENO[3,2- d]PYRIMIDINONES. Қўқон ДПИ. Илмий хабарлар, 8(9), 826-834. https://doi.org/10.70728/a.series.tab.v08.i09.107
GOST (OAK)Anvarjon, Buronov, Azizbek, Nasrullaev, Khurshed, Bozorov DESIGN OF NOVEL TRICYCLIC ARYLIDENE THIENO[3,2- d]PYRIMIDINONES // Қўқон ДПИ. Илмий хабарлар. – 2026. – T. 8, № 9. – P. 826-834. – DOI: 10.70728/a.series.tab.v08.i09.107.
MLAAnvarjon, Buronov, Azizbek, Nasrullaev, and Khurshed, Bozorov. “DESIGN OF NOVEL TRICYCLIC ARYLIDENE THIENO[3,2- d]PYRIMIDINONES.” Қўқон ДПИ. Илмий хабарлар, 8(9), 826-834, 2026. https://doi.org/10.70728/a.series.tab.v08.i09.107
ChicagoAnvarjon, Buronov, Azizbek, Nasrullaev, and Khurshed, Bozorov. “DESIGN OF NOVEL TRICYCLIC ARYLIDENE THIENO[3,2- d]PYRIMIDINONES.” Қўқон ДПИ. Илмий хабарлар, 8(9), 826-834 (2026). https://doi.org/10.70728/a.series.tab.v08.i09.107
HarvardAnvarjon, Buronov, Azizbek, Nasrullaev, and Khurshed, Bozorov (2026) ‘DESIGN OF NOVEL TRICYCLIC ARYLIDENE THIENO[3,2- d]PYRIMIDINONES’, Қўқон ДПИ. Илмий хабарлар, 8(9), 826-834. https://doi.org/10.70728/a.series.tab.v08.i09.107
BibTeX
@article{anvarjonburonov2026,
  title = {DESIGN OF NOVEL TRICYCLIC ARYLIDENE THIENO[3,2- d]PYRIMIDINONES},
  author = {Anvarjon, Buronov and Azizbek, Nasrullaev and Khurshed, Bozorov},
  journal = {Қўқон ДПИ. Илмий хабарлар},
  year = {2026},
  volume = {8},
  number = {9},
  pages = {826-834},
  doi = {10.70728/a.series.tab.v08.i09.107},
  url = {https://doi.org/10.70728/a.series.tab.v08.i09.107}
}

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