This study assesses the influence of psycho-emotional stress on the immune mechanisms of the development of psoriasis in order to determine the relationship between stress load, the activation of neuroendocrine pathways and Th17-mediated inflammation. The analysis was carried out by comparing patients with psoriasis who had high and low levels of psycho-emotional stress. On the basis of clinical indices, psychometric scales and immunological indicators, the degree of the influence of stress on disease activity and on specific immune mechanisms was determined. The levels of cortisol, neuropeptides and key pro-inflammatory cytokines and the population of Th17 cells were analysed using correlation analysis. In addition, stable relationships between stress markers and the clinical activity of psoriasis were identified, which is an important indicator for the development of comprehensive psychoimmune therapeutic strategies.
| Mualliflar | Kurbanov Shaxboz Ilxomovich, Tolibov Mansur Maxmudovich, Курбанов Шахбоз Ильхомович, Толибов Мансур Махмудович, Kurbanov Shaxboz Ilxomovich, Tolibov Mansur Maxmudovich |
|---|---|
| Jurnal | Research Focus |
| Nashriyot | Ветеринария ИТИ ва “Илм-фан ва инновациялар академияси” МЧЖ |
| ISSN | 2181-3833 |
| Nashr sanasi | 2025-12-05 |
| Jild | 4 |
| Son | 11 |
| Betlar | 314-320 |
| Til | Ingliz |
| Ilmiy soha | Veterinariya |
| DOI | 10.66073/researchfocus.v4i11.1872 |
| Indeksga qo‘shilgan | 2026-09-08 |
DOI: 10.66073/researchfocus.v4i11.1872 · Maqolaning asl sahifasi
псориаз, психоэмоциональный стресс, нейроэндокринная регуляция, HPA-ось, IL-17A, IL-23, TNF-α, Th17-клетки, Substance P, цитокиновый профиль, нейрогенное воспаление, клиническая активность, psoriasis, psycho-emotional stress, neuroendocrine regulation, HPA axis, IL-17A, IL-23, TNF-α, Th17 cells, Substance P, cytokine profile, neurogenic inflammation, clinical activity, psoriaz, psixoemotsional stress, neyroendokrin boshqaruv, HPA o'qi, IL-17A, IL-23, TNF-α, Th17-hujayralar, Substance P, sitokin profili, neyrogen yallig'lanish, klinik faollik
| APA | Kurbanov Shaxboz Ilxomovich, Tolibov Mansur Maxmudovich, Курбанов Шахбоз Ильхомович, Толибов Мансур Махмудович, Kurbanov Shaxboz Ilxomovich, & Tolibov Mansur Maxmudovich (2025). THE INFLUENCE OF PSYCHOEMOTIONAL STRESS ON THE IMMUNE MECHANISMS OF PSORIASIS DEVELOPMENT. Research Focus, 4(11), 314-320. https://doi.org/10.66073/researchfocus.v4i11.1872 |
|---|---|
| GOST (OAK) | Kurbanov Shaxboz Ilxomovich va b. THE INFLUENCE OF PSYCHOEMOTIONAL STRESS ON THE IMMUNE MECHANISMS OF PSORIASIS DEVELOPMENT // Research Focus. – 2025. – T. 4, № 11. – P. 314-320. – DOI: 10.66073/researchfocus.v4i11.1872. |
| MLA | Kurbanov Shaxboz Ilxomovich, Tolibov Mansur Maxmudovich, Курбанов Шахбоз Ильхомович, Толибов Мансур Махмудович, Kurbanov Shaxboz Ilxomovich, and Tolibov Mansur Maxmudovich. “THE INFLUENCE OF PSYCHOEMOTIONAL STRESS ON THE IMMUNE MECHANISMS OF PSORIASIS DEVELOPMENT.” Research Focus, 4(11), 314-320, 2025. https://doi.org/10.66073/researchfocus.v4i11.1872 |
| Chicago | Kurbanov Shaxboz Ilxomovich, Tolibov Mansur Maxmudovich, Курбанов Шахбоз Ильхомович, Толибов Мансур Махмудович, Kurbanov Shaxboz Ilxomovich, and Tolibov Mansur Maxmudovich. “THE INFLUENCE OF PSYCHOEMOTIONAL STRESS ON THE IMMUNE MECHANISMS OF PSORIASIS DEVELOPMENT.” Research Focus, 4(11), 314-320 (2025). https://doi.org/10.66073/researchfocus.v4i11.1872 |
| Harvard | Kurbanov Shaxboz Ilxomovich, Tolibov Mansur Maxmudovich, Курбанов Шахбоз Ильхомович, Толибов Мансур Махмудович, Kurbanov Shaxboz Ilxomovich, and Tolibov Mansur Maxmudovich (2025) ‘THE INFLUENCE OF PSYCHOEMOTIONAL STRESS ON THE IMMUNE MECHANISMS OF PSORIASIS DEVELOPMENT’, Research Focus, 4(11), 314-320. https://doi.org/10.66073/researchfocus.v4i11.1872 |
| BibTeX | @article{kurbanovshaxbozilxomovich2025,
title = {THE INFLUENCE OF PSYCHOEMOTIONAL STRESS ON THE IMMUNE MECHANISMS OF PSORIASIS DEVELOPMENT},
author = {Kurbanov Shaxboz Ilxomovich and Tolibov Mansur Maxmudovich and Курбанов Шахбоз Ильхомович and Толибов Мансур Махмудович and Kurbanov Shaxboz Ilxomovich and Tolibov Mansur Maxmudovich},
journal = {Research Focus},
year = {2025},
volume = {4},
number = {11},
pages = {314-320},
doi = {10.66073/researchfocus.v4i11.1872},
url = {https://doi.org/10.66073/researchfocus.v4i11.1872}
} |
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