The role of oxidative stress and mitochondrial dysfunction in the progression of alopecia

Isayev Jasurbek Muzaffarovich, Oripov Rustam Anvarovich, Исаев Джасурбек Музаффарович, Орипов Рустам Анварович, Isayev Jasurbek Muzaffarovich, Oripov Rustam Anvarovich

Research Focus · 2025-yil

Annotatsiya

This study presents a comprehensive assessment of the role of oxidative stress and mitochondrial dysfunction in the progression of androgenetic alopecia and alopecia areata in order to determine their relationship with the clinical parameters of the disease. The analysis was carried out by comparing patients with different forms of alopecia and a control group. On the basis of clinical, biochemical and morphological data, the degree of oxidative damage, the severity of mitochondrial disorders and their correlation with the severity of the disease were determined. The level of lipid peroxidation, the activity of the antioxidant system and the indicators of mitochondrial function were analysed using statistical methods. In addition, specific differences between the forms of alopecia were identified, which is an important pathogenetic and prognostic indicator.

Maqola ma’lumotlari
MualliflarIsayev Jasurbek Muzaffarovich, Oripov Rustam Anvarovich, Исаев Джасурбек Музаффарович, Орипов Рустам Анварович, Isayev Jasurbek Muzaffarovich, Oripov Rustam Anvarovich
JurnalResearch Focus
NashriyotВетеринария ИТИ ва “Илм-фан ва инновациялар академияси” МЧЖ
ISSN2181-3833
Nashr sanasi2025-12-05
Jild4
Son11
Betlar306-313
TilIngliz
Ilmiy sohaVeterinariya
DOI10.66073/researchfocus.v4i11.1871
Indeksga qo‘shilgan2026-09-08

DOI: 10.66073/researchfocus.v4i11.1871 · Maqolaning asl sahifasi

Kalit so‘zlar

алопеция, андрогенетическая алопеция, очаговая алопеция, оксидативный стресс, митохондриальная дисфункция, малоновый диальдегид, mtDNA, ΔΨm, апоптоз, 8-OHdG, caspase-3, трихоскопия, alopecia, androgenetic alopecia, alopecia areata, oxidative stress, mitochondrial dysfunction, malondialdehyde, mtDNA, ΔΨm, apoptosis, 8-OHdG, caspase-3, trichoscopy, alopetsiya, androgenetik alopetsiya, o'choqli alopetsiya, oksidativ stress, mitoxondrial disfunksiya, malon dialdegid, mtDNA, ΔΨm, apoptoz, 8-OHdG, caspase-3, trixoskopiya

Ilmiy soha

Veterinariya

Iqtibos keltirish

APAIsayev Jasurbek Muzaffarovich, Oripov Rustam Anvarovich, Исаев Джасурбек Музаффарович, Орипов Рустам Анварович, Isayev Jasurbek Muzaffarovich, & Oripov Rustam Anvarovich (2025). THE ROLE OF OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION IN THE PROGRESSION OF ALOPECIA. Research Focus, 4(11), 306-313. https://doi.org/10.66073/researchfocus.v4i11.1871
GOST (OAK)Isayev Jasurbek Muzaffarovich va b. THE ROLE OF OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION IN THE PROGRESSION OF ALOPECIA // Research Focus. – 2025. – T. 4, № 11. – P. 306-313. – DOI: 10.66073/researchfocus.v4i11.1871.
MLAIsayev Jasurbek Muzaffarovich, Oripov Rustam Anvarovich, Исаев Джасурбек Музаффарович, Орипов Рустам Анварович, Isayev Jasurbek Muzaffarovich, and Oripov Rustam Anvarovich. “THE ROLE OF OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION IN THE PROGRESSION OF ALOPECIA.” Research Focus, 4(11), 306-313, 2025. https://doi.org/10.66073/researchfocus.v4i11.1871
ChicagoIsayev Jasurbek Muzaffarovich, Oripov Rustam Anvarovich, Исаев Джасурбек Музаффарович, Орипов Рустам Анварович, Isayev Jasurbek Muzaffarovich, and Oripov Rustam Anvarovich. “THE ROLE OF OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION IN THE PROGRESSION OF ALOPECIA.” Research Focus, 4(11), 306-313 (2025). https://doi.org/10.66073/researchfocus.v4i11.1871
HarvardIsayev Jasurbek Muzaffarovich, Oripov Rustam Anvarovich, Исаев Джасурбек Музаффарович, Орипов Рустам Анварович, Isayev Jasurbek Muzaffarovich, and Oripov Rustam Anvarovich (2025) ‘THE ROLE OF OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION IN THE PROGRESSION OF ALOPECIA’, Research Focus, 4(11), 306-313. https://doi.org/10.66073/researchfocus.v4i11.1871
BibTeX
@article{isayevjasurbekmuzaffarovich2025,
  title = {THE ROLE OF OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION IN THE PROGRESSION OF ALOPECIA},
  author = {Isayev Jasurbek Muzaffarovich and Oripov Rustam Anvarovich and Исаев Джасурбек Музаффарович and Орипов Рустам Анварович and Isayev Jasurbek Muzaffarovich and Oripov Rustam Anvarovich},
  journal = {Research Focus},
  year = {2025},
  volume = {4},
  number = {11},
  pages = {306-313},
  doi = {10.66073/researchfocus.v4i11.1871},
  url = {https://doi.org/10.66073/researchfocus.v4i11.1871}
}

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