This study investigates the changes in cognitive and affective functions in patients with generalized epilepsy, with a particular focus on the therapeutic effects of lacosamide. A total of 100 patients were enrolled and divided into three groups based on the duration of epilepsy. Cognitive functions were assessed using the Montreal Cognitive Assessment (MoCA), while affective symptoms, particularly depression, were evaluated with the Hamilton Depression Rating Scale (HDRS). The findings revealed that patients receiving lacosamide showed better cognitive performance and lower levels of depressive symptoms compared to those not on lacosamide. Although longer disease duration was associated with greater cognitive and affective decline, lacosamide significantly mitigated these effects. These results highlight lacosamide’s potential not only in reducing seizure frequency but also in improving neuropsychological well-being, emphasizing the need for comprehensive clinical approaches in managing generalized epilepsy.
| Mualliflar | Файзиева Раъногул Ходжи кизи, Азизова Раъно Бахoдировна |
|---|---|
| Jurnal | Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research |
| Nashriyot | Бухоро давлат тиббиёт институти |
| Nashr sanasi | 2025-06-26 |
| Jild | 6 |
| Son | 4 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-10-05 |
генерализованная эпилепсия, когнитивные нарушения, депрессия, лакосамид, противоэпилептическая терапия, тест MoCA, шкала HDRS, generalized epilepsy, cognitive impairment, depression, lacosamide, antiepileptic therapy, MoCA test, HDRS scale, generallashgan epilepsiya, kognitiv buzilishlar, depressiya, lakosamid, antiepileptik terapiya, MoCA testi, HDRS shkalasi
| APA | Файзиева Раъногул Ходжи кизи, & Азизова Раъно Бахoдировна (2025). “OPTIMIZING THE CLINICAL MANAGEMENT OF COGNITIVE AND AFFECTIVE DISORDERS IN GENERALIZED EPILEPSY”. Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(4). https://tadqiqot.uz/index.php/neurology/article/view/11637 |
|---|---|
| GOST (OAK) | Файзиева Раъногул Ходжи кизи, Азизова Раъно Бахoдировна “OPTIMIZING THE CLINICAL MANAGEMENT OF COGNITIVE AND AFFECTIVE DISORDERS IN GENERALIZED EPILEPSY” // Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research. – 2025. – T. 6, № 4. |
| MLA | Файзиева Раъногул Ходжи кизи, and Азизова Раъно Бахoдировна. ““OPTIMIZING THE CLINICAL MANAGEMENT OF COGNITIVE AND AFFECTIVE DISORDERS IN GENERALIZED EPILEPSY”.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(4), 2025. https://tadqiqot.uz/index.php/neurology/article/view/11637 |
| Chicago | Файзиева Раъногул Ходжи кизи, and Азизова Раъно Бахoдировна. ““OPTIMIZING THE CLINICAL MANAGEMENT OF COGNITIVE AND AFFECTIVE DISORDERS IN GENERALIZED EPILEPSY”.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(4) (2025). https://tadqiqot.uz/index.php/neurology/article/view/11637 |
| Harvard | Файзиева Раъногул Ходжи кизи, and Азизова Раъно Бахoдировна (2025) ‘“OPTIMIZING THE CLINICAL MANAGEMENT OF COGNITIVE AND AFFECTIVE DISORDERS IN GENERALIZED EPILEPSY”’, Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(4). https://tadqiqot.uz/index.php/neurology/article/view/11637 |
| BibTeX | @article{article2025,
title = {“OPTIMIZING THE CLINICAL MANAGEMENT OF COGNITIVE AND AFFECTIVE DISORDERS IN GENERALIZED EPILEPSY”},
author = {Файзиева Раъногул Ходжи кизи and Азизова Раъно Бахoдировна},
journal = {Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research},
year = {2025},
volume = {6},
number = {4},
url = {https://tadqiqot.uz/index.php/neurology/article/view/11637}
} |
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