Studying the polymorphism RS17576 MMP-9 genein patients with type 2 diabetes mellitus after myocardial infarction

Khusanov , Ravshan Axrorovich

Гуманитар ва табиий фанлар журнали · 2025-yil

Annotatsiya

The aim of our study was to evaluate the role of polymorphism rs17576 MMP-9 gene in patients with type 2 diabetes mellitus after myocardial infarction (MI). In patients with type 2 diabetes mellitus after myocardial infarction 86 Uzbeks have been studied the alleles and genotypes rs17576 MMP-9 gene. According to it, according to the result of the oddsratio (OR - odds ratio), in carriers of the minor allele G the probability of developing the disease decreased by 29% (OR =0.71, 95% CI: 0.45-1.12), this means that the minor allele G has a protective effect against the development of coronary heart disease. On the other hand, the wild-type A allele of the MMP-9 gene polymorphism rs17576 increased the like-lihood ofdeveloping MI by 42% (OR = 1.42; 95% CI: 0.91-2.21) and turned out to be a significant risk factor for developing MI.

Maqola ma’lumotlari
MualliflarKhusanov , Ravshan Axrorovich
JurnalГуманитар ва табиий фанлар журнали
NashriyotEMU University
ISSN2026-2027, 2181-4007
Nashr sanasi2025-03-14
Son19
Betlar275-278
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

Matrix metalloproteinases, Type 2 diabetes mellitus, Myocardial infarction, Gene.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAKhusanov , Ravshan Axrorovich (2025). STUDYING THE POLYMORPHISM RS17576 MMP-9 GENEIN PATIENTS WITH TYPE 2 DIABETES MELLITUS AFTER MYOCARDIAL INFARCTION. Гуманитар ва табиий фанлар журнали, (19), 275-278. https://journals.tnmu.uz/index.php/gtfj/article/view/1303
GOST (OAK)Khusanov , Ravshan Axrorovich STUDYING THE POLYMORPHISM RS17576 MMP-9 GENEIN PATIENTS WITH TYPE 2 DIABETES MELLITUS AFTER MYOCARDIAL INFARCTION // Гуманитар ва табиий фанлар журнали. – 2025. – № 19. – P. 275-278.
MLAKhusanov , Ravshan Axrorovich. “STUDYING THE POLYMORPHISM RS17576 MMP-9 GENEIN PATIENTS WITH TYPE 2 DIABETES MELLITUS AFTER MYOCARDIAL INFARCTION.” Гуманитар ва табиий фанлар журнали, (19), 275-278, 2025. https://journals.tnmu.uz/index.php/gtfj/article/view/1303
ChicagoKhusanov , Ravshan Axrorovich. “STUDYING THE POLYMORPHISM RS17576 MMP-9 GENEIN PATIENTS WITH TYPE 2 DIABETES MELLITUS AFTER MYOCARDIAL INFARCTION.” Гуманитар ва табиий фанлар журнали, (19), 275-278 (2025). https://journals.tnmu.uz/index.php/gtfj/article/view/1303
HarvardKhusanov , Ravshan Axrorovich (2025) ‘STUDYING THE POLYMORPHISM RS17576 MMP-9 GENEIN PATIENTS WITH TYPE 2 DIABETES MELLITUS AFTER MYOCARDIAL INFARCTION’, Гуманитар ва табиий фанлар журнали, (19), 275-278. https://journals.tnmu.uz/index.php/gtfj/article/view/1303
BibTeX
@article{khusanovravshanaxrorovich2025,
  title = {STUDYING THE POLYMORPHISM RS17576 MMP-9 GENEIN PATIENTS WITH TYPE 2 DIABETES MELLITUS AFTER MYOCARDIAL INFARCTION},
  author = {Khusanov , Ravshan Axrorovich},
  journal = {Гуманитар ва табиий фанлар журнали},
  year = {2025},
  number = {19},
  pages = {275-278},
  url = {https://journals.tnmu.uz/index.php/gtfj/article/view/1303}
}

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